This is the third report of the findings of the investigation we made in Tokushima Prefecture as part of a joint research project designed to work up measures against the problems of the elderly with urinary incontinence in rural areas. The project, led by Dr.Kazunori Sugiyama, was commissioned by the National Mutual Insurance Federation of Agricultural Cooperatives (Zenkyoren).
The two previously published reports dealt with (1) independence of the elderly in rural community and urination trouble and (2) urinary incontinence in the elderly populace of a rural area.
Of the elderly men living at home, 20.5% was found to have urinary incontinence and a further 14.4% complained about difficulty in urinating. Those who registered an IPSS count of 10 or over accounted for 20.1% of the urinary incontinent persons. The IPSS showed a tendency to go up with advancing age. To be noted was the fact that there is a regional difference in the average score. It was lower in the mountain villages than in the flat-land farming areas. This suggested that the incidence of prostatic hypertrophy may be low in the mountain villages than in the flat-land areas.
In prostate examination, the use of IPSS is helpful in screening for enlargement of the prostate to some extend. More clinically dependable tools are ultrasonography, cystourethroscopy (cystoscopy) and uroflowmetry. However, whether these tools should be introduced for first-line screening is debatable.
In contrast, blood tests that measure levels of PSA and PAP are not only effective but also feasible for mass screening. Thus, the authors would like to recommend their immediate implementation in health screening programs for the elderly.

It is assumed that keishikaryojutsubuto was first described in the Ho-ki medical text, and it has been used to target neuralgia and the arthritic pain. We experienced cases of Crohn's disease, endometriosis, post-operative rectal carcinoma, acute gastroenteritis and Meniere's disease successfully treated with keishikaryojutsubuto. When this formulation is administered, it might be important to keep in mind the definition of prescriptions for keishikashakuyakuto and shimbuto, or ryokeijutsukanto, as described in the Kokan-igaku text. In addition, this formulation might be applicable to various other diseases.
symptoms <1> ; Application, NOS ; Acute ; Pain ; Meniere's Disease

The first study on chemical constituents and biological activities of Clausena lansium (Lour.) Skeels (Rutaceae) growing in Vietnam has been done. Phytochemical investigation of n-hexane extract led to the isolation of five compounds: dihydroindicolactone (1), 8-geranyloxy psoralen (2), imperatorin (3), heraclenol (4) and indicolactone (5), in which this is the first report on the presence of dihydroindicolactone (1). Their structures were elucidated based on LC/MS/NMR hyphenated techniques as well as comparison with those of literature data. The n-hexane extract and its subfractions, ethanol 95% extract and several isolated compounds were evaluated for antifungal activity.
Clausena* ; Ethanol ; Ficusin ; Vietnam