1.An Opinion Poll of Doctors Concerning Working Conditions in Kohseiren Hospitals and the Medical Service System in Japan.
Kenji KATAGIRI ; Satoshi WAKITA ; Takeshi YOKOI ; Higashi SUGIMOTO ; Hirofumi TAHARA ; Tatsuya HAGA ; Masahiro IKEUCHI ; Hitoshi KANAYAMA ; Kohji OHHASHI ; Masaaki IKEDO
Journal of the Japanese Association of Rural Medicine 2002;51(4):633-650
A survey was conducted by sending questionnaires to 466 doctors working at nine hospitals affiliated with the Aichi Prefectural Federation of Agricultural Cooperatives for Health and Welfare (Kohseiren).
The survey found that the length of service was under 5 years in 60% of the respondents and that many of them identified themselves strongly with the department of the teaching hospital where they were trained.
They were found to be little intersted in the present situation of the agricultural cooperatives and Japanese agriculture. However, they said they were satisfied with the present working conditions, because they could show their skills. Most approved of organ transplants after brain death but disapproved of human cloning. They showed a positive attitude toward the allowing of each patient to give access to his or her clinical records and standardization of medical treatment. Some 67% of the doctors admitted they had made medical mistakes and keenly realized the necessity of risk management.
While feeling uneasy about the recent upsurge of lawsuits brought by patients about medical treatment, they said they are endeavoring to provide safe and high quality medical service. Their recent concerns were rearrangement of dispensaries based on the subspecialty, reinforcement of postgraduate courses in medical schools and the postgraduate training system which will be a legal obligation from 2005. They suported the reform plans for the national medical service for aged patients and recognized the necessity of joining hands with local agricultural cooperatives in providing nursing care services. They said they wish to continue their career as a physican at the Kohseiren hospital.
2.Oxidized human serum albumin as a possible correlation factor for atherosclerosis in a rural Japanese population: the results of the Yakumo Study.
Ryosuke FUJII ; Jun UEYAMA ; Arisa AOI ; Naohiro ICHINO ; Keisuke OSAKABE ; Keiko SUGIMOTO ; Koji SUZUKI ; Nobuyuki HAMAJIMA ; Kenji WAKAI ; Takaaki KONDO
Environmental Health and Preventive Medicine 2018;23(1):1-1
BACKGROUND:
The effect of the redox state of human serum albumin (HSA) on the antioxidant properties of the entire body has been a focus of recent research. The usefulness of HSA redox state as a biomarker for reducing oxidative stress has been investigated in clinical settings; however, evidence for its significance as a health index in non-clinical settings is yet to be established. This study aimed to examine the associations between HSA redox state and the atherosclerotic indices of carotid intima-media thickness (IMT) and plaque formation in a rural Japanese population.
METHODS:
We conducted a cross-sectional study as part of a health check-up program in the rural area of Hokkaido, Japan, at the end of August 2013. A total of 281 residents (124 men and 157 women) were included in the final analysis. Lifestyle-related data were obtained through a self-reported questionnaire, and ultrasound examinations were performed to measure IMT and determine plaque formation. The high-performance liquid chromatography postcolumn bromocresol green method was used to separate HSA into human nonmercaptalbumin and human mercaptalbumin (HMA).
RESULTS:
We found a significant negative relationship between the fraction of HMA [f(HMA)] and IMT (standardized β = - 0.132, p = 0.03). Moreover, f(HMA) was significantly associated with plaque formation (p < 0.01) with an odds ratio of 0.89 (95% confidence interval, 0.81-0.97) for every 10% increment in f(HMA).
CONCLUSIONS
We found that the HSA redox state, as determined by f(HMA), was associated with atherosclerotic indices in Japanese subjects. These results suggest that the HSA redox state indicates the risk of developing atherosclerosis.
Adult
;
Aged
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Aged, 80 and over
;
Atherosclerosis
;
epidemiology
;
etiology
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Biomarkers
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Carotid Intima-Media Thickness
;
statistics & numerical data
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Cross-Sectional Studies
;
Female
;
Humans
;
Japan
;
epidemiology
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Male
;
Middle Aged
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Oxidation-Reduction
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Risk Factors
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Serum Albumin
;
metabolism
;
Serum Albumin, Human
;
metabolism