1.Application of quality control circle in location of management of material in operating room
Xiufang ZOU ; Heyu WU ; Yesong XIA
Modern Clinical Nursing 2015;(6):62-64,65
Objective To explore the effect of quality control circle (ACC) on the management of material in the operation room. Method QCC team was established in operation room to consistently improve the location and position of material, and standards of locating and positioning the material were established. Results Through the application of QCC, the satisfaction rates of nurses and doctors were higher than those before QCC. The preoperative time for material preparation after the application of QCC was significantly shorter than that before (P<0.01). Conclusion Through the implementation of QCC, the locations of material in the operating room are standardized, and the quality of operating room management and nurses'work efficiency both improved.
2.Nursing cooperation of immediate breast reconstruction with the latissimus dorsi myocutaneous flap
Lin JIAN ; Heyu WU ; Xiao LIU ; Hong LIU
Modern Clinical Nursing 2016;15(4):12-14,15
Objective To summarize the experience of nursing cooperation for immediate breast reconstruction with the latissimus dorsi myocutaneous flap. Methods Twenty breast cancer patients underwent modified radical surgery with intraoperative immediate application of the latissimus dorsi myocutaneous flap in combination with the same period breast prosthesis for breast reconstruction. The nursing measures included preoperative preparation and mental support, intraoperative active cooperation, position care, sustaining of body temperature and strict aseptic and disease-free technology. Results All the breast cancer patients lived through breast cancer modified radical immediate breast reconstruction. No flap necrosis occurred , neither did obvious complications. The operations were satisfactory. Conclusion The key to the breast reconstruction for the breast cancer patients exists in preoperative psychological nursing , intraoperative strict aseptic and disease-free technology , the proper operation position and the correct use of instruments and equipment.
3.Application of disposable surgery retractor made of high polymer medical plastic
Ying YANG ; Lihua LIAO ; Tingting HE ; Heyu WU ; Xinglian GAO
Journal of Regional Anatomy and Operative Surgery 2017;26(6):458-460
Objective To analyze the application effect of disposable surgery retractor which made of high polymer medical plastic.Methods From January 2016 to October 2016,80 patients of HCC who were treated with hepatectomy under general anesthesia in our hospital were randomly divided into the control group and the observation group according to different retractor during surgery.The control group used the traditional abdominal retractor during the sugery.Meanwhile,the observation group used disposable surgery retractor.The application effect between the two groups were compared.Results The satisfaction rate of surgical exposure and effect in surgeon of the observation group were higher than those of the control group.The wound pain time of patients in perioperative period and 1 month after surgery and chronic pain incidence in postoperative 6 months between the two groups were evaluated.It turned out that the difference in average pain score was statistically significant (P<0.05).Conclusion The disposable surgical retractor can improve the satisfaction rate of surgeons with better surgical exposure,and it can significantly reduce the damage of wound tissue,which effectively relieves the postoperative pain,shortens the time of postoperative pain,and reduces the incidence of chronic pain.
4.Warming nursing to severe traumatic patients with hypothermia and nursing measures
Heyu WU ; Li WU ; Ling JIAN ; Ping WANG ; Hong LIU ; Ling YE
Modern Clinical Nursing 2016;15(11):31-35
Objective To investigate the causes of hypothermia in severe trauma patients as well as the effects of warming nursing.Methods Toally 100 severe trauma patients with hypothermia were engaged in the study during January to December 2014.Their temperature was monitored and recorded,the causes analyzed so that the warming nursing measures were done to them.Results Among the 100 patients,59 contracted hypothermia,with the rate of 59.0% before operation,28 contracted hypothermia during operation,with the incidence rate of 28.0%.The causes of hypothermia included injury,anaesthesia,exposure and fluid resuscitation.The nursing measures included pre-treatment before anaesthesia,avoidance of more exposure and intraoperative warming.Conclusions For the patients with severe trauma,the hypothermia during the operation can be caused by injury,anaesthesia,exposure and fluid resuscitation.The warming nursing can reduce the incidence of hypothermia so as to increase their survival rate.
5.Detection of platelet fibronectin from congenital fibrinogenopenic patients and its clinical significance.
Kaiyang DING ; Jingsheng WU ; Zhimin ZHAI ; Xiucai XU ; Zimin SUN ; Mingli WANG ; Heyu NI
Chinese Journal of Hematology 2002;23(3):143-146
OBJECTIVETo assess the platelet and plasma concentrations of fibronectin (Fn) and fibrinogen (Fg) in congenital fibrinogenopenic (FgP) patients and explore their role in inducing platelet adhesion and aggregation.
METHODSA FgP family was selected as study group and the platelets isolated and purified to assess concentrations of Fn and Fg in platelets, alpha-granules and plasma with Western blotting, immuofluoresence staining and flow cytometry (FACS), respectively, the expression of platelets GP II b/III a by FACS.
RESULTSThe concentration of platelets Fn in FgP patients is higher than that in controls, and is higher in homozygote than in heterozygote. In contrast, plasma Fn levels were identical in all samples. The amount of platelet Fg from FgP patients is lower than that from the controls and positively correlated with the concentration of their plasma Fg. No difference in the expression of platelet GP II b/III a had been found.
CONCLUSIONIt suggested that increased platelet Fn could partially compensate the lack of Fg and lead the platelet adhesion and aggregation.
Afibrinogenemia ; congenital ; metabolism ; pathology ; Blood Platelets ; metabolism ; pathology ; Cell Adhesion ; physiology ; Female ; Fibrinogen ; genetics ; metabolism ; Fibronectins ; blood ; genetics ; metabolism ; Heterozygote ; Homozygote ; Humans ; Male ; Pedigree ; Platelet Aggregation ; physiology ; Platelet Membrane Glycoproteins ; metabolism
6. Research progress on risk factors and risk assessment of venous thrombosis in patients undergoing gynecological surgery
Luping CUI ; Heyu WU ; Jie CHU
Chinese Journal of Practical Nursing 2020;36(5):396-401
There is a high incidence of venous thrombosis in patients undergoing gynecological surgery, which causes symptoms as limbs swelling, edema and pain. Postoperative recovery of patients is delayed and financial burden is increased More seriously, the obstruction of pulmonary artery by deep venous thrombosis is fatal and always leads to the death of patients. The article provides a theoretical basis for the prevention of venous thrombosis by reviewing the risk factors and risk assessment for venous thrombosis in patients undergoing gynecological surgery and related research progress.
7.Establishment and application of an ORTCC model-based training system for orthopedic subspecialty nurses in the operating room
Heyu WU ; Ying YANG ; Qiong MA ; Shiyu ZHAO ; Juanjuan HU ; Qi ZHOU
Chinese Journal of Practical Nursing 2023;39(8):567-572
Objective:To explore the construction and clinical practice of the training system for nurses in operating room subspecialty based on ORTCC model (including objectives, rules, training, assessment and culture), and to provide theoretical and practical guidance for the development of nursing subspecialty in operating room.Methods:This was a quasi-experimental study. The Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology was convenient to select 23 operating room nurses who rotated in orthopedic surgery rooms from January 2019 to June 2020 as the control group, and the traditional training model for specialized nurses in operating rooms was adopted. From July 2020 to December 2021, the 24 operating room nurses rotating orthopedic surgery rooms were selected as the experimental group, and ORTCC teaching mode was adopted. The degree of mastery of theoretical knowledge, standardization of operation skills, correct rate of standard preventive implementation and satisfaction rate of doctors of operating room nurses under two different training methods were compared.Results:The theoretical score of operating room nurses increased from (84.71 ± 5.70) points in the control group to (92.68 ± 3.64) points in the experimental group, and the skill score increased from (90.17 ± 4.69) points in the control group to (95.43 ± 2.61) points in the experimental group, with statistical significance ( t = 13.76, 5.64, both P<0.01). The satisfaction rate of surgeons to nurses′ surgical cooperation ability communication, cooperation ability and emergency treatment ability increased from 82.61%(19/23), 73.91%(17/23) and 78.26%(18/23) in the control group to 100.00%(24/24), 95.83% (24/24) and 100.00% (24/24) in the experimental group, respectively, with statistically significant differences ( t = 4.56, 4.45, 5.84, all P<0.05). Conclusions:The training system of operating room subspecialty nurses based on ORTCC model is conducive to improving the theoretical knowledge mastery, standard operation skills and doctor satisfaction rate of operating room nurses to the specialty and subspecialty, providing training basis for the development of operating room subspecialty, and worthy of clinical promotion.
8.Lycorine alleviates oxaliplatin-induced chemotherapy induced pain in mice via reducing COX-2 /NLRP3 inflammatory signaling
Chenlu Guo ; Ji Wu ; Heyu Yang ; Min Xie ; Ling Liu
Acta Universitatis Medicinalis Anhui 2023;58(3):429-433,441
Objective:
To explore the effect and mechanism of lycorine on oxaliplatin ( OXA) induced chemotherapy pain in mice.
Methods :
40 mice were randomly divided into 4 groups,10 mice per group,which were respectively divided into control group,model group,administration group,and inhibitor group.A mouse model of chemotherapy induced pain was established by intraperitoneal injection of OXA for 5 consecutive days.Intrathecal administration of lycorine was performed.Behavioral changes and expression levels of inflammatory related proteins were detected .
Results :
Compared with control group,model group mice exhibited the increased number of spontaneous flinches,decreased mechanical nociceptive threshold,decreased movement distance and latency,and up-regulated expression levels of interleukin-1 β (IL-1 β) ,astrocytic marker glial fibrillary acidic protein ( GFAP) ,cyclooxygenase-2( COX-2) ,NOD-like receptor protein 3 ( NLRP3 ) ,cysteinyl aspartate and specific proteinase 1 ( Caspase- 1) .Compared with model group,lycorine administration reduced the number of spontaneous flinches,increased mechanical nociceptive threshold ,enhanced the movement distance and latency ,bound and reduced COX-2 expression,down-regulated the expression levels of IL-1 β , GFAP ,NLRP3 and Caspase-1.
Conclusion
Lycorine reduces COX-2 expression,inhibits NLRP3 inflammasome activation,suppresses spinal inflammation,consequently alleviates pain behaviors and improved motor ability of mice.