1.A randomized study camparing oral versus injection triamcinolone in carpal tunnel syndrome
Dewi ; Henny Anggraini Sadeli ; Nani Kurniani ; Suryani Gunadharma
Neurology Asia 2009;14(2):121-127
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy found in clinical practice.
Corticosteroids are effective in treating CTS. The purpose of this study was to evaluate the effi cacy of
oral versus local injection of triamcinolone in relieving symptoms and improving neurophysiological
parameters in CTS. This is a randomized controlled trial performed at Hasan Sadikin Hospital, Bandung.
Inclusion criteria were idiopathic CTS patients without thenar atrophy and no contraindications to
corticosteroids. Subjects were divided into oral or injection groups. The oral group was given 16
mg triamcinolone daily for 2 weeks followed by 8 mg daily for the next 2 weeks and local placebo
injection. The injection group was given 15 mg local injection triamcinolone and oral placebo. The
outcome was assessed using Global Symptom Score and nerve conduction studies. Fifty subjects were
randomized to oral or injection group. The injection group show signifi cant improvement at 2 and 4
weeks while the oral group showed signifi cant improvement only at 2 weeks. Comparing both groups,
improvement in neurophysiological parameters were signifi cantly greater in the injection group.
In conclusion, local injection triamcinolone show better neurophysiologic outcome and effi cacy in
relieving symptoms compared to oral triamcinolone in CTS.
2.Characteristics of neuropathic pain in Indonesia: A hospital based national clinical survey
Thomas Eko Purwata ; Henny A Sadeli ; Yudiyanta ; Yuneldi Anwar ; Darwin Amir ; Chris Asnawi ; Suroto ; Dani Rahmawati ; Leksmono Partoatmodjo ; Susi Aulina ; Putu Eka Widyadarma ; Moch Dalhar ; Endang Mutiawati ; Theresia Runtuwene ; Lucas Meliala ; Andradi Suryamihardja ; Agus Permadi ; Fredy Sitorus ; Untung Gunarto ; Yusak Mangara Tua Siahaan ; Edison Marpaung ; Yulius Mandua
Neurology Asia 2015;20(3):389-394
We conducted a hospital based study to collect data on the clinical characteristics of neuropathic
pain (NP) patients in neurology outpatients in 13 big cities in Indonesia. We aimed to identify the
clinical characteristics of NP among patients with the symptoms of pain. A simple questionnaire was
conducted to explore the clinical symptoms and signs. Participants who reported of NP symptom was
1,779 (21.8%) among 8,160 patients. The higher prevalence of NP was reported in 41-60 years old
(n= 1,030; 57.9%). It was more prevalent in male (n=1,104; 62.1%). The group of patients with low
educational level has higher prevalence of pain with NP (n=1,177; 66.1%). There are five main clinical
symptoms of NP patients, pinprick sensation (n=589; 33.1%), electric shock like sensation (n=542,
30.5%), burning (n=407, 22.9%), paresthesia (n=401; 22.5%) and hyperalgesia (n=351, 19.7%). In
this study, NP was mostly associated with low back pain (n=509, 28,6%), carpal tunnel syndrome
(n=343; 19.3%), frozen shoulder syndrome (n=191, 10.7%), diabetic neuropathy (n=170, 9.6%) and
brachialgia (n=108, 6.1%). The most frequent modality to treat NP symptoms were adjuvant analgesics,
antidepressants or anticonvulsants (n=1,199; 67.4%), non-steroidal anti-inflammatory drugs (n=1,177,
66.2%), non-opioids analgesics (n=606; 34.1%), non-pharmacological treatment (n=366; 20.6%) and
opioid treatments (n=100, 5.6%).
3.Characteristics of neuropathic pain in Indonesia: A hospital based national clinical survey
Thomas Eko Purwata ; Henny A Sadeli ; Yudiyanta ; Yuneldi Anwar ; Darwin Amir ; Chris Asnawi ; Suroto ; Dani Rahmawati ; Leksmono Partoatmodjo ; Susi Aulina ; Putu Eka Widyadarma ; Moch Dalhar ; Endang Mutiawati ; Theresia Runtuwene ; Lucas Meliala ; Andradi Suryamihardja ; Agus Permadi ; Fredy Sitorus ; Untung Gunarto ; Yusak Mangara Tua Siahaan ; Edison Marpaung ; Yulius Mandua
Neurology Asia 2015;20(4):389-394
We conducted a hospital based study to collect data on the clinical characteristics of neuropathic
pain (NP) patients in neurology outpatients in 13 big cities in Indonesia. We aimed to identify the
clinical characteristics of NP among patients with the symptoms of pain. A simple questionnaire was
conducted to explore the clinical symptoms and signs. Participants who reported of NP symptom was
1,779 (21.8%) among 8,160 patients. The higher prevalence of NP was reported in 41-60 years old
(n= 1,030; 57.9%). It was more prevalent in male (n=1,104; 62.1%). The group of patients with low
educational level has higher prevalence of pain with NP (n=1,177; 66.1%). There are five main clinical
symptoms of NP patients, pinprick sensation (n=589; 33.1%), electric shock like sensation (n=542,
30.5%), burning (n=407, 22.9%), paresthesia (n=401; 22.5%) and hyperalgesia (n=351, 19.7%). In
this study, NP was mostly associated with low back pain (n=509, 28,6%), carpal tunnel syndrome
(n=343; 19.3%), frozen shoulder syndrome (n=191, 10.7%), diabetic neuropathy (n=170, 9.6%) and
brachialgia (n=108, 6.1%). The most frequent modality to treat NP symptoms were adjuvant analgesics,
antidepressants or anticonvulsants (n=1,199; 67.4%), non-steroidal anti-inflammatory drugs (n=1,177,
66.2%), non-opioids analgesics (n=606; 34.1%), non-pharmacological treatment (n=366; 20.6%) and
opioid treatments (n=100, 5.6%).
Neuralgia