Objective To study the effects of integrated liposomal prostagladin E 1(Lipo PGE 1) and fosinopril on early diabetic nephropathy (DN) and clinical DN.Methods 86 patients of type 2 diabetic patients with DN were randomly divided into control group (fosinopril) and treated group(fosinopril+Lipo PGE 1).UARE,Scr and BUN figures were compared between two groups before treatment and eight weeks after treatment.Results UAER had been decreased significantly in both groups(P0.05).Furthermore,no significant decrease of BUN、FBG、MPA、TC and TG had been found in both groups.Conclusion Integrated Lipo PGE 1and fosinopril can ameliorate proteinuria and improve renal function of the patients with early DN and clinical DN of normal renal function.

Objective To observe the differences in functional areas of the brain in response to two different acupuncture techniques using functional magnetic resonance imaging (fMRI).Methods Deqi and non-deqi acupuncture were performed on twenty healthy right-handed volunteers.fMRI was conducted in the process of acupuncture.The experiment adopted a single-chunk design and the procedure contained periods of stimulation and rest.The brain regions stimulated during deqi and non-deqi acupuncture were assessed using xjview software.Results After acupuncture at the Zusanli point (ST36),differences in activity were observed between the deqi and non-deqi groups in the language,sports,perception and limbic systems.Conclusions ①Under deqi conditions,acupuncture at ST36 increases circulation and the activation of brain areas dealing with language,sports,perception and the limbic system.This may be one of the mechanisms by which acupuncture can improve aphasia,coordination and perception.②Under deqi conditions acupuncture at ST36 decreases circulation and deactivates brain areas associated with the limbic system.This may explain acupuncture's analgesia and regulation of autonomic nerve and endocrine function,its amelioration of internal organ functions and regulation of immunologic function.