Objective To study effect of self-care ability and subjective well-being of Based on peer support surgery nursing intervention for ICU surgery patients. Methods A total of172 cases patients with ICU surgery from July 2014 to June 2015 were divided into observation group and control group, the observation group given based on peer support nursing intervention, the control group routine nursing intervention, and followed up for 6 months, self-care ability, anxiety, depression, and subjective well- being were compared between two groups. Results Followed up for 6 months, the observation group life attitude, life style, diet adjustment, treatment compliance were (79.92 ± 7.23), (82.36 ± 7.15), (83.57±7.25), (85.73±7.45) points, significantly higher than the control group (72.25±7.12), (74.79±6.89), (73.66±7.08), (76.68±7.13) points, (t=7.010-9.069, P<0.01). Anxiety and depression scores were 47.16± 4.27, 48.58±5.32,which were significantly lower than the control group 50.48±4.56, 53.37±5.75 (t=4.928, 5.671, P<0.05). Health worry, life satisfaction and interests, energy, sad or happy mood, emotion and behavior control, relaxation and tension, subjective well-being scored 8.12±0.95, 7.68±0.85, 16.45±2.31, 13.02±1.24,13.25±1.33, 17.56±2.45, 78.69±8.02, were significantly higher than the control group 7.52± 0.82, 6.31±0.72,13.25±1.22, 12.35±1.22, 12.02±1.21, 14.36±1.42, 67.12±7.02 (t=3.572-11.405, P<0.05 or 0.01). Conclusions Based on peer support surgery nursing intervention help to improve self-care ability of surgery patients, alleviate the negative mood, and improve subjective well-being.

Objective To investigate the influencing factors of children pneumonia hospitalization expense and provide refer‐ence for its expense control .Methods Path analysis was performed on the hospitalization expense and its influencing factors based on 927 pneumonia children in a hospital in Chongqing in 2011 .Results Multivariate regression analyasis showed that the influen‐cing factors of children pneumonia hospitalization expense were proportion of drug expense ,length of hospital stay ,type of pay‐ment ,admission condition ,therapeutic outcome and age .The coefficient of determination (R2 =0 .867 ,F=597 .552 ,P<0 .01) .Be‐sides ,proportion of drugs ,admission condition and therapeutic outcome had indirect effects by influencing hospital stay .The coeffi‐cient of determination (R2 =0 .506 F=330 .336 ,P<0 .01) .According to the total coefficient of path analysis ,the factors of influen‐cing hospitalization expense were listed in descending order as follows :proportion of drug expense ,length of hospital stay ,therapeu‐tic outcome ,type of payment ,admission condition and age .Conclusion Reducing drug proportion ,length of hospital stay ,and strengthening supervision on medicare patients′ expense are effective measurements to control children pneumonia hospitalization ex penses .

Using Low Shear-30 rheometer, we studied apparent viscosities at high (51.2-128.5s~(-1)), moderate (11.02-37.6s~(-1)), and Low (0.376-8.11s~(-1)) shear rate, viscoelastic properties of whole blood and hemodynamic parameters in 10 patients with acute myocardiac infarction(AMI), comparing with 10 patients with angina pectoris (AP) and 11 normal subjects(NS). It was demostrated that the apparent viscosities of whole blood at different shear rates mentionned above and viscoelastic properties of whole blood (the dynamic modulus G′, the loss modulus G″, "the viscous ?′ and the elastic component ?″ of complex viscosity) increased distinctly and parameters of cardiac function (EF, CO, LVET, PEP/LVET, HI, SV and CI) were abnormal obviously in AMI, in comparing with AP and NS (P

Relationship between hemorheology and blood gas analysis was studied in 37aged patients with chronic cor pulmonale, including 17 instable and 20 stable. Apparentviscosity (?a) of shear rate of 230.4 (?a(H)) and 5.76/s (?a(L)), TK values, redcell aggregation index(RAI) and PaCO_2 in instable chronic cor pulmonale (AG) were muchhigher than that of stable. patients (BG). Oxygen delivery index (OD) and PaO_2 in AGwere lower than in BG. ?a (H) was negatively correlated with OD and pH (r=-0.58,-0.40, P

External fixators have been widely u sed in treatment of war trauma due to t heir small size,light weight,easy application,and convenience in transport.There are several types of military external fixato r,such as FESSA(Fixateur Externe du Service de Sant?des Arm?es),CMC(Croatian Medical Corps),Synthes and Hoffman-Ⅱ.All of these have been used on the battlefields of Rwandese War,Croatia Wa r and the first Persian Gulf War.Most of military external fixators are unilateral connectable-joint.For temp orary fixation,one bar is enough;by adding another parallel bar,the fixation can be use d for long-time fixing.Facing with a great demand of war trauma treatment ,we should develop new types of military external fixator with more simplicity and less size or weight. [

Objective Vascular endothelial growth factor( VEGF) is the key to regulat vascularization, and plays an important role in the development of acute myeloid leukemia. With the understanding of anti?tumor angiopoiesis, researchers take VEGF and its receptors as targets, continuously exploring the new drug. We summarized the biological characteristics of VEGF, vascular?targeted therapy and the clinical application of drugs.

BACKGROUND:The existing bone grafting apparatus are al long tubular-shape, antegrade bone grafting; however, the bone grains within the tube were difficult to put through, along with large bone loss. OBJECTIVE:To design a new concept of minimaly invasive bone grafting apparatus, so as to achieve the minimaly invasive bone grafting in vertebral body and intervertebral space. METHODS: On Solidworks 2012 software platform, the 3D three-dimensional solid modeling technology was employed to design a new concept of gun-shape bone grafting device with the characteristics of headend reversely placing at the grafting position and antegrade pushout, against the problems such as antegrade bone grafting, long bone grafting path and difficulty in bone grafting existing in precious percutaneous or/and transpedicular bone graft apparatus. The virtual assembly and simulative bone grafting surgery were performed with the bone grafting apparatus for observation of the instrument matching degree and grafting surgical procedures. RESULTS AND CONCLUSION: A set of minimaly invasive gun-shape bone grafting apparatus was successfuly designed; its length was 20 cm in total; the length of the front semi-closed bone tube was 2.5 cm. There are two kinds of diameter specifications: inner diameter of 3.5 mm/outer diameter of 4 mm, and inner diameter of 5 mm/outer diameter of 6 mm. Virtual assembly revealed that the grafting apparatus were wel matched. Stimulative surgery displayed that the bone grain loading and launch were simple. The gun-shape bone grafting device is reasonable in design, avoiding pushing too long distance, bone pushing difficulties, bone loss and other problems in previous tubular bone grafting apparatus. Percutaneous, endoscopic vertebrae or intervertebral space minimaly invasive bone grafting can be performed with this apparatus.

BACKGROUND: The application of polymerized 2-hydroxyethyl methacryate (PHEMA) in many organs of living body shows good biocompatibility.OBJECTIVE: To observe the biocompatibility and fibrovascular condition of methl-methacrylate (MMA) modified PHEMA hydrogel orbital implant.DESIGN: Single sample observation.SETTING: Department of Ophthalmology, the General Hospital of Chinese PLA; Institute of Polymer Science,Department of Chemical Engineering, Tinghua university.MATERIALS: Twenty-five New Zealand rabbits of either gender and clean grade, weighing 2.0 to 2.5 kg, were provided by the Animal Experimental Center, General Hospital of Chinese PLA. The animals were observed at postoperative 2, 4,8, 12 and 24 weeks, 5 at each time point. The experiment was permitted by ethics committee. MMA modified PHEMA hydrogel orbital implant was provided by Institute of Polymer Research, Department of Chemical Engineering, Tinghua University. The experiment was permitted by ethics committee.METHODS: This experiment was carried out in the laboratory of Department of Ophthalmology, the General Hospital of Chinese PLA from March to October 2003. The right eye served as operation eye. When the rabbits were anesthetized,their eyelids were open with eyelid retractor. Bulbar conjunctiva was open along the edge of limbus of cornea for isolating fascia. Oculorotatory muscle was isolated and pre-set suture line was made, then muscle was cut off. When optical nerve was cut off, eyeball was completely excised. A MMA modified PHEMA hydrogel orbital implant with the diameter of 14 mm was implanted into the fossa orbitalis of rabbits. Single photon emission computed tomography (SPECT) was performed at postoperative 2, 4, 8, 12 and 24 weeks. The hydrogel orbital implant was taken out at postoperative 2, 4, 8,12 and 24 weeks for light microscope, immunohistochemical and electron microscope examinations.MAIN OUTCOME MEASURES: Vascularization of hydrogel orbital implant was observed in vivo by isotope tracing observation at different time points. Vascularization of hydrogel orbital implant was observed ex vivo by light microscope,immunohistochemical and electron microscope observations.RESULTS: All 25 New Zealand rabbits were involved in the final analysis. ①SPECT examination showed that isotope increased around the implants at week 2, and extended gradually at weeks 4 and 8. The radiotracer accumulated evenly in the implants from surrounding to the center at week 12. ②Light microscopic examination of the prostheses revealed fiber vessels grew from the surrounding to the center. At week 2,fibrovascular tissue grew in the hole of implant. Long or round cells with deeply dyed nucleuses were found in the hole, being fibroblasts. The vascular structure in the hole of the implant was clear, and vascular wall and blood cells were found. The inflammatory cells were mainly neutrophils and lymphocytes, and occasionally large macrophages. ③Scanning electron microscope showed that fibrovascular tissue grew in the hole of the implant, and was dense and intercrossed at week 12. ④ Conjunctiva split appeared postoperatively in 1 of 25 cases, and healed well after two times of operation. Conjunctival congestion lessened and conjunctiva healed within postoperative 7 days in the remaining 24 animals.CONCLUSION: MMA modified PHEMA hydrogel orbital implant has good histocompatibility and fast vascularization process, and is easy to be operated with fewer complications. So, it is a safe and practicable new type orbital implant.

The antimutagenicity of 14 compounds, cysteine (1), cinnamic acid (2), rutin (3), tannic acid (4), germanium dioxide (5),fluoro uracil (6), sodium copper chlorophylline (7),?-sitosterol (8), vitamin C (9), coumarin (10), vitamin E (11), L-glutathine (oxidized form) (12), L-glutathine (reduced form) (13) and organic germanium (14), were investigated using Salmonella typhimurium/microsome assay in TA100.Three modes of action, i.e. inhibitory, antimutagenic and desmutagenic effects, were observed-for their antimutagenicity. Results showed that all of test compounds inhibited mutagenicity induced by MNNG and B(a)P with the exception of germanium dioxide. Percent inhibition of compounds 1, 2, 3, 4, 6, 8, 10 and 12 were greater than 90%. 14 compounds exhibited antimutagenic effects on the mutagenic activity of MNNG, and 12 compounds exhibited antimutagenic effects on B(a)P. Germanium dioxide and organic germanium had no such effect. 14 compounds all exerted desmutagenic effects on B (a)P directly before B(a)P acted on cells. According to the potential and modes of action, cysteine, cinnamic acid, rutin, tannic acid and coumarin were better among 14 compounds. The doseresponse relationships of inhibitory and antimutagenic effects on mutation induced by MNNG and B(a)P were found. Each compound has its sufficient range of dosage. These studies suggest that it is necessary to select effective antimutagens to make mixtures, and their synergistic effects should be investigated.

Objective To recognize the factors which influence the therapeutic efficacy of transurethral resection of the prostate (TURP) and to improve the qualities of TURP. Methods The data of 600 patients with benign prostatic hyperplasia (BPH) were retrospectively studied based on the mastering of TURP.The patients’age ranged from 52 to 92 years,with a mean of 64.8 years.Preoperatively,the volume of the prostate was 16.3～210.4 ml,with a mean of 46.2 ml,measured by color Doppler B-ultrasound.The average maximum urinary flow rate (Qmax) was 8.4 ml/s,and average urinary flow rate (Qave) was 4.3 ml/s.The average residual urinary volume (RU) was 75 ml,and the average IPSS was 23. Results TURP was successfully performed on all the 600 patients.The average resected prostate tissue weight was 31.8 g.The average electric ablation time was 51 minutes.Intraoperative blood transfusion was performed in 38 cases. Aura of transurethral resection syndrome (TURS) occurred in 4 cases,but no TURS occurred.Of the 600 cases,508 cases (85%) were followed up for 1～32 months.Postoperative average Qmax increased to 16.9 ml/s,Qave increased to 10.8 ml/s and RU decreased to 15 ml.Compared with those of preoperation,the differences were statistically significant (P