1.Functional Outcome With Percutaneous Ilio-sacral Screw Fixation For Posterior Pelvic Ring Injuries In Patients Involved In Heavy Manual Laboring
Abhishek SM ; Prashanth ; Azhar AL ; Vijay GB ; Harshal K
Malaysian Orthopaedic Journal 2015;9(3):23-27
Introduction: Unstable posterior pelvic ring injuries are best
treated with operative methods due to better post-op
functional score. Our patient cohort was involved in heavy
manual laboring frequently required ground level work in
their activities of daily living. There are very few outcome
studies dealing exclusively with such patients.
Materials & Methods: Forty one patients who were treated
with percutaneous sacroiliac screw fixation under
fluoroscopic guidance and were followed-up for at least one
year were analyzed retrospectively for functional outcome
using the Majeed score.
Results: Twenty one (51.22%) and thirteen (31.70%) patients
were found to be in excellent and good categories
respectively and majority of the patients (thirty/73.17%)
were able to return to their original occupation with or
without minor adjustments.
Conclusion: Percutaneous ilio-sacral screw fixation for
posterior pelvic unstable injuries is an acceptable mode of
treatment in patients involved in heavy manual laboring.
laboring
Pelvic Infection
2.Telmisartan-induced sprue-like enteropathy: a case report and a review of patients using non-olmesartan angiotensin receptor blockers.
Harshal Surendra MANDAVDHARE ; Vishal SHARMA ; Kaushal K PRASAD ; Amit KUMAR ; Manish RATHI ; Surinder S RANA
Intestinal Research 2017;15(3):419-421
Recent studies have identified sprue-like illness associated with the use of the antihypertensive agent olmesartan medoxomil. However, whether this condition is specific to the use of olmesartan or is associated with the use of drugs belonging to the class of “sartans” remains to be clarified. A 45-year-old woman with chronic kidney disease along with hypothyroidism and hypertension presented with chronic diarrhea and significant weight loss. Endoscopy of the upper gastrointestinal tract showed scalloping and grooving of the duodenum, and histopathological examination showed subtotal villous atrophy. She was on telmisartan for hypertension, which was discontinued. Subsequently, diarrhea ameliorated dramatically, and she regained weight. To our knowledge, this is the first study to report telmisartan-associated sprue-like enteropathy. Further, we have reviewed the cases of patients with sprue-like enteropathy caused by valsartan, irbesartan, and eprosartan.
Angiotensin Receptor Antagonists*
;
Angiotensins*
;
Atrophy
;
Celiac Disease
;
Diarrhea
;
Duodenum
;
Endoscopy
;
Female
;
Humans
;
Hypertension
;
Hypothyroidism
;
Middle Aged
;
Olmesartan Medoxomil
;
Pectinidae
;
Renal Insufficiency, Chronic
;
Upper Gastrointestinal Tract
;
Valsartan
;
Weight Loss
3.Role of Decompression in Late Presentation of Cervical Spinal Cord Disorders.
Sandeep SHRIVASTAVA ; Harshal SAKALE ; Rajesh DULANI ; Pradeep K SINGH ; Manoj SANRAKHIA
Asian Spine Journal 2014;8(2):183-189
STUDY DESIGN: Prospective study conducted at Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, India. PURPOSE: To show the efficacy of decompression in the late presentation of cervical spinal cord disorders. OVERVIEW OF LITERATURE: Studies by various authors have shown that early spinal decompression results in better neurological outcomes. METHODS: From January 2003 to January 2005, 11 of the 41 patients with cervical spinal cord compression, meeting the inclusion criteria, underwent anterior decompression; interbody graft placement and stabilization by anterior cervical locking plate. The neurologic and functional outcomes were recorded. RESULTS: Five patients had spinal cord injury and 6 patients had compressive cervical myelopathy. Complications included 1 death and 1 plate loosening. No patient lost their preoperative neurological status. One patient had no improvement, 2 patients showed full recovery. The mean follow-up is 28.3 month. At the of rehabilitation, 6 were able to walk without support), 2 could walk with support, and 1 needed a wheelchair. The average American Spinal Injury Association motor score on admission to the hospital, 32.8 (standard deviation [SD], 30.5); admission to rehabilitation, 38.6 (SD, 32.4); discharge from rehabilitation, 46.2 (SD, 33.7). The most recent follow-up was 64.0 (SD, 35.3). CONCLUSIONS: The anterior approach for cervical decompression allows for adequate decompression. This decompression is the best chance offered in even late reported cases, including posttraumatic cases where there is no evidence of cord transactions. The use of anterior cervical plates reduces the chances of graft loosening, extruding, or collapsing.
Cervical Vertebrae
;
Decompression*
;
Decompression, Surgical
;
Female
;
Follow-Up Studies
;
Humans
;
India
;
Neglected Diseases
;
Prospective Studies
;
Quadriplegia
;
Rehabilitation
;
Spinal Cord Compression
;
Spinal Cord Diseases*
;
Spinal Cord Injuries
;
Spinal Cord*
;
Spinal Injuries
;
Transplants
;
Wheelchairs
4.Sarcopenia is common in ulcerative colitis and correlates with disease activity
Pardhu B NEELAM ; Rimesh PAL ; Pankaj GUPTA ; Anupam K SINGH ; Jimil SHAH ; Harshal S MANDAVDHARE ; Harjeet SINGH ; Aravind SEKAR ; Sanjay K BHADADA ; Usha DUTTA ; Vishal SHARMA
Intestinal Research 2024;22(2):162-171
Background/Aims:
Association of sarcopenia with disease severity in ulcerative colitis (UC) is not clearly defined. We planned to estimate the prevalence of sarcopenia in patients with UC as per the revised definition and its relation with the disease severity.
Methods:
A cross-sectional assessment of sarcopenia in patients with UC was performed. Disease activity was graded according to complete Mayo score. Hand grip strength was assessed with Jamar hand dynamometer, muscle mass using a dual energy X-ray absorptiometry scan, and physical performance with 4-m walk test. Sarcopenia was defined as a reduction of both muscle mass and strength. Severe sarcopenia was defined as reduced gait speed in presence of sarcopenia.
Results:
Of 114 patients (62 males, mean age: 36.49±12.41 years), 32 (28%) were in remission, 46 (40.4%) had mild-moderate activity, and 36 (31.6%) had severe UC. Forty-three patients (37.7%) had probable sarcopenia, 25 (21.9%) had sarcopenia, and 14 (12.2%) had severe sarcopenia. Prevalence of sarcopenia was higher in active disease (2 in remission, 6 in active, and 17 in severe, P<0.001). Of 14 with severe sarcopenia, 13 had severe UC while 1 had moderate UC. On multivariate analysis, lower body mass index and higher Mayo score were associated with sarcopenia. Of 37 patients with acute severe colitis, 16 had sarcopenia. Requirement of second-line therapy was similar between patients with and without sarcopenia. On follow-up (median: 18 months), there was a non-significant higher rate of major adverse events in those with sarcopenia (47.4% vs. 33.8%, P=0.273).
Conclusions
Sarcopenia and severe sarcopenia in UC correlate with the disease activity.
5.Gastrointestinal histoplasmosis: a case series from a non-endemic region in North India
Harshal S MANDAVDHARE ; Jimil SHAH ; Kaushal K PRASAD ; Roshan AGARWALA ; Vikas SURI ; Savita KUMARI ; Usha DUTTA ; Vishal SHARMA
Intestinal Research 2019;17(1):149-152
No abstract available.
Histoplasmosis
;
India