1.Association between left ventricular hypertrophy and peritoneal transport properties in peritoneal dialysis patients
Hongtao CHEN ; Haogui HUANG ; Dan ZHU ; Qijun WAN ; Yongcheng HE
Clinical Medicine of China 2014;30(11):1172-1175
Objective To investigate the association between left ventricular hypertrophy and peritoneal transport properties in Peritoneal Dialysis patients.Methods Sixty-nine Continuous Ambulatory Peritoneal Dialysis (CAPD)patients were enrolled in current study.All patients underwent echocardiography for left ventricular mass index (LVMI).Transport status was categorized as high transport,high average transport,low average transport and low transport based on modified peritoneal equilibration test (PET).The data collected included hemoglobin,albumin,blood urea nitrogen,creatinine,urea clearance (Kt/V) and creatinine clearance rate (Ccr),dialysis vintage,systolic blood pressure,diastolic blood pressure.Results Patients with high transport status were 41 cases,more than those with low transport status(28 cases).The dialysis age of high transport,high average transport,low average transport and low transport vintage were (39.2 ± 21.8),(26.6 ±15.6),(28.6 ± 14.4),(45.7 ± 35.0) years old respectively,and the difference was significant (F =4.128,P < 0.05).The dialysis age in the higher transport group was longer than that in high average transport group and low average transport group (P < 0.05).LVMI has significant positive correlations with D/Pcr at 4th hour,SBP and DBP (r =0.339,0.351,0.316,P < 0.01) and the negative correlation with albmin (r =-0.292,P <0.05).Left ventricular hypertrophy(LVH) in all patients was 63.8%,ant it was higher in high transport group than that low average transport and low transport group (x2 =5.455,5.091,P < 0.05) Conclusion High transport status is the most common in CAPD patients.There is high incident rate of LVH in this population.LVH has significant positive correlations with D/Pcr,higher SBP,DBP,and lower albumin.