1.Concepts and Problems of Gait Rehabilitation Robots for Stroke
Huawei LIU ; Huifang WANG ; Jinjie ZHU ; Jiajia YAO ; Yi SUN ; Haofeng SHEN ; Xiaojia ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2013;19(5):493-494
The gait rehabilitation robots for stroke are responding to the development of the understanding of stroke rehabilitation, but still some challenges for application may be faced to, as found in AutoAmbulator. Some advices were dicussed from the view of the practice.
2.Action verb processing for exciting the motor cortex and promoting the recovery of upper limb function after stroke
Sicong ZHANG ; Xiangtong JI ; Quan WANG ; Haofeng SHEN ; Yixi ZHU ; Ruiping HU ; Wei CHEN ; Tifei YUAN ; Chunlei SHAN
Chinese Journal of Physical Medicine and Rehabilitation 2017;39(6):412-417
Objective To explore the effect of action verb processing on the excitability of the motor cortex and any effect on the upper limb motor function of stroke survivors.Methods Experiment 1:The motor evoked potential by transcranial magnetic stimulation (TMS-MEP) was measured while 18 healthy subjects were processing concrete action verbs or abstract verbs.Experiment 2:Eight hemiplegic stroke survivors were asked to read silently text describing concrete hand actions,and then repeat and explain the meaning of the action verbs used in the text.This was repeated for 30 minutes per day,5 days per week for 3 weeks.In the 2nd week the same training was conducted except that the text was about abstract verbs.The modified Ashworth scale (MAS),Fugl-Meyer assessment (FMA),the Hong Kong version of the functional test for a hemiplegic upper extremity (FTHUE-HK) and a simple test for evaluating hand function (STEF) were used to assess upper limb motor function before and after the training each week.Results Experiment 1:Processing the concrete action verbs induced significantly greater MEP than processing the abstract verbs.Experiment 2:The average FMA and STEF ratings improved significantly after the training each week.Training with the concrete action verbs resulted in significantly better FMA and STEF scores than with the abstract verbs.The average MAS score increased significantly week by week.There was significantly more improvement in the average FTHUE-HK rating after the 1st and 3rd week of training than after the 2nd week.Conclusion Action verb processing induces greater motor cortex excitation than abstract verb processing among healthy subjects and better improves the upper limb motor function of stroke survivors.
3.Crystal structure of monkeypox H1 phosphatase, an antiviral drug target.
Wen CUI ; Haojun HUANG ; Yinkai DUAN ; Zhi LUO ; Haofeng WANG ; Tenan ZHANG ; Henry C NGUYEN ; Wei SHEN ; Dan SU ; Xi LI ; Xiaoyun JI ; Haitao YANG ; Wei WANG
Protein & Cell 2023;14(6):469-472