Objective To observe the effect of different volume cerebrospinal fluid replacement therapy on subarachnoid hemorrhage. Methods 60 patients were randomly divided into two groups, A group(n=30) and B group (n=30). Patients in A group received cerebrospinal fluid replacement with a total replacement of 50-70ml each time. Patients in B group received cerebrospinal fluid replacement with a total replacement of 10 - 30ml each time.Results The period to relieve headache in A group was shorter significantly than in B group(P 0.05). The total effect rate of A group was significantly higher than that of B group( P

Objective To improve the understanding of perioperative anesthesia management in patients with anti-N-methyl-D-aspartate receptor encephalitis combined with a history of ovarian teratoma.Methods Case information of 10 patients with anti-N-methyl-D-aspartate receptor encephalitis with a history of ovarian teratoma admitted to the Third Affiliated hospital of Sun yat-sen University from July 2014 to November 2018 were retrospectively analyzed.Results A total of 10 patients received treatment,8 improved after treatment,2 had poor prognosis,and their families required discharge.All patients received endotracheal intubation under general anesthesia.Conclusions Anesthesiologists should pay attention to perioperative anesthesia management of patients with anti-N-methyl-D-aspartate receptor encephalitis complicated with ovarian teratoma,including preoperative evaluation,anesthesia methods and drug selection,intraoperative and postoperative management.