1.The Observation on Therapeutic Effects for Blood Component Transfusion Applied to Treat Acute Leukemia Complicated with DIC
Journal of Chinese Physician 2001;0(04):-
Objective To study the therapeutic effects of blood component transfusions on acute leukemia complicated with DIC.Methods The blood component transfusions were mainly used to treat 11 patients with acute aranulocytic leukemia and acute lymphatic leukemia complicated with DIC.Results Three cases were cured,one case were obviously effective,two were improved and five were ineffective,which the total effective rate was 54 5% .Conclusion Early diagnosis and blood component transfusions in timely are effective methods to treat the acute leukemia patients complicated with DIC
2.Autosecretion of the Fresh Leukemic Cells from Patients with Acute Myeloid Leukemia in Vitro and Apoptosis in the Cells
Jianming TANG ; Anwei CHEN ; Haode LI
Journal of Chinese Physician 2000;0(11):-
To investigate the effects of granulocyte macrophage colony stimulating factor (GM-CSF) which was secreted from the fresh leukemic cells of patients with acute myeloid leukemia (AML) and recombinant human GM-CSF(rhGM-CSF) on the apoptosis of the primary incubative AML cells,the level of GM-CSF was measured by means of radioimmunoassay,the DNA ladder was detected by using DNA electrophoresis,and the percentage of apoptotic cells,percentage of expression and the mean fluorescence intensity(MFI) of bcl-2 were respectively assayed by means of flow cytomtric analysis.After the fresh leukemic cells from 5 cases were incubated for 24 hours,GM-CSF in 3 of 5 cases were seen,their percentage of apoptotic cells was less than the other 2 cases,and the MFI of bcl-2 in the 3 of 5 cases was obviously enhanced.After the fresh leukemic cells were treated with cytarabine (Ara-C) 5?g/ml in combination with rhGM-CSF 5?g/ml for 24 hours,the percentage of apoptotic cells was more than the cells treated with Ara-C alone and it upward to (56 4?7 4)%(p
3.Preparation and Quality Control of Dexamethasone Acetate Borneol Cream
Renfa JIANG ; Ning TAO ; Chang YU ; Ke LI ; Haode FENG
China Pharmacy 1991;0(04):-
OBJECTIVE:To prepare dexamethasone acetate borneol cream and to establish its quality control method.METHODS:Dexamethasone acetate borneol cream was prepared by grinding method;dexamethasone acetate and phenol were identified by TLC,and the content of the principal agent was determined by ultraviolet spectrophotometry.RESULTS:The prepared cream fitted the description of China Pharmacopeia(2005 edition) in identification and tests etc.The linear range of dexamethasone acetate was 12.06~28.14 ?g?mL-1(r=0.999 7),and the average recovery rate of 98.52%(RSD=0.66%).CONCLUSION:The preparation is reasonable in compounding,simple and feasible in techniques,and its quality is stable and controllable.
4.Clinical Observation of Weixiao Mixture for Functional Dyspepsia
Yongshu JIANG ; Renfa JIANG ; Haode FENG ; Jiabin DENG ; Ke LI ; Anyan YAO ; Shaoya HE
China Pharmacy 1991;0(04):-
OBJECTIVE:To observe the therapeutic effect of Weixiao mixture on functional dyspepsia.METHODS:In a single-blind design,patients were randomly divided into Weixiao mixture group and domperidone group to compare the ther?apeutic effect between two preparations.RESULTS:The total effective rates were83.87%for Weixiao mixture group and75.00%for domperidone group(P