The objective of this study is to obtain a comprehensive understand the view of inservice education master degree program students on their supervisors' performance in teaching and research in Peking University Health Science Centre.on their.This study was conducted by using the questionnaire-based survey which includes questions regarding research quality,research conditions and scientific spirit etc.We concluded that Peking University Health Science Center,by formulating practical regulations and adopting relevant policies,managed to keep the capacity building for the supervisors and will further improve quality of the in-service graduate program.

Objective To investigate the clinical effects and operation key-points of interphalangeal joint replacement arthroplasty for the treatment of traumatic arthritis.Methods From March 2005 to December 2010,5 patients with post-traumatic arthritis undergoing interphalangeal joint replacement arthroplasty in our hospital were selected.The operation indications,treatment of intraoperative flexor and extensor tendon lesion and postoperative rehabilitation were evaluated.Results Operative incisions of 5 cases were primary healing in class I grade A.Stitches were taken out 2 weeks after the operation.Patients were followed up for 1.5 years.The range of interphalangeal joint motion was 0 to 90 (extension/flexion) with no pain at end of follow-up.The hand function was excellent in 3 cases and good in 2 cases according to total active motion (TAM)hand function evaluation.Conclusions Interphalangeal joint replacement arthroplasty is an effective treatment for traumatic arthritis.Preoperative indications evaluation and postoperative rehabilitation should be focused on the treatment.

Actual research on brain-computer interface system is analyzed.The basic structure and operational principle of this system are set forth.Methods of signal collection,feature extraction and selection classification of system signals are concluded.Latest analysis methods and existing defects of feature extraction and selection classification are introduced in detail.Problems existing in brain-computer interface system are also analyzed.Great advantages on feature extraction of wavelet transform & wavelet packet decomposition and wide prospects on selection classification of neural network are pointed out at last.

Objective To investigate the influence of ozagrel sodium (OS) on cerebral ischemic tolerance in rat induced by focal ischemic preconditioning (IPC) and on expression of nuclear factor ?B (NF ?B) in rats Methods Fourty five rats were divided into 3 groups The animals were subjected to 2 h middle cerebral artery occlusion (MCAO) 3 days after 10 min IPC, IPC+OS and sham surgery (SS) respectively. After 22 h reperfusion, the rats were killed and the infarct volume, brain water content and NF ?B immunoreactivity were compared among 3 groups. Results Compared with IPC+ MCAO group, there were a furtber decrements in farct volume (93 75?13 40 vs 130 92?14 59, P

Estrogen receptor(ER),an important transcription factor belonging to the nuclear receptor superfamily,comprises two subtypes ER?and ER?.Estrogen receptor is expressed in prostate cancer and ladder cancer and has a compacted relationship with them.In this review,we summarized the structure,distri- bution,function of different estrogen receptor subtypes and progress in study on relationship between different estrogen receptor subtypes and prostate or bladder cancer.

Objective To longitudinally analyze the unit costs and technical efficiency of the model of male circumcision in the different kinds of persons .Methods Unit costs were calculated by the person and period using longitudinal data from 3 kinds of persons ,and then technical efficiency and Malmquist indices were measured with an approach to data envelopment analysis . Results Theunit costs for changing the willingness to accept surgery changed dramatically ,decreasing from 7 166 .67 yuan(mean) to 737 .31 yuan ,while the costs for changing the ratio of the surgery increased from 666 .64 yuan (mean) to 744 .58 yuan ,and its technical efficiency was averaging between 0 .95-0 .96 .Conclusion The time series of unit costs for changing the willingness to ac-cept surgery dramatically dropped ,while changing the ratio of the surgery formed a U-shape curve with an inflection point before which unit costs dramatically dropped and another inflection point beyond which unit costs went up .These findings can inform pro-gram managers of the changing unit costs when extending or expanding the program .

Objective To observe the therapeutic effects of stellate ganglion block (SGB) with oxycodone and acetaminophen tablets on the treatment of migraine. Methods 100 patients with migraine were divided into two groups randomly. They received SGB with oxycodone and acetaminophen tablets (experimental group) or only SGB (control group) respectively. The parameters included pain intensity before and 1 d,3 d,1 w,1 m and 3 m after the treatment, and pain relief rate of each patient. The adverse effects were also evaluated. Results The pain intensity described as numeric rating score (NRS) decreased in the two groups at each time point. In the experimental group, the value of NRS was significantly less than that in the control group at 3d,1m and 3m after the treatment. The effec-tive rate ha the experimental group and the control group were 88% and 68%. Conclusion SGB with oxycodone and acetaminophen tablets is more effective for migraine and deserves widely used in patients.

Objective To introduce a better operation method to repair the skin and soft tissue defects in the forehead.Methods This kind of frontalis musculocutaneous flap was applied to repair the skin and soft tissue defects in the forehead in 8 cases.The flap was designed carefully according to the shape and the size of the focal lesion before the operation. The maximum area of the flap was 2.9cm?1.6cm, and the minimum area was 1.2cm?1cm. The full flap contained muscle in its proximal area and skin, muscle, and fascia in its distal one. A muscular pedicle with appropriate length was outlined on the paramedian and lateral forehead. The pedicle was composed of frontalis muscle fibers, the terminal part of the frontal branches of the superficial temporal artery, and some small branches from the supraorbital and the supratrocheal arteries. The body of the flap was designed into triangle shape. Full thickness skin was incised around the inverted pattern of the defect. The skin of the paramedian and lateral aspect was then undermined laterally. Superficial dissection was carried out in a subcutaneous layer. The flap was undermined beneath the galea and frontalis muscle just external to the skull. The muscle pedicle was prepared by incising a parallel horizontal incision. Careful attention should be taken so as not to injure the vascular pedicle. At that time, the supraorbital and supratrocheal arteries were carefully ligated to obtain complete hemostasis. Then the flap was advanced and transferred down to cover the wound in the forehead. The donor site could be sutured directedly by undermining the margins of the defect without much difficuties. Results All flaps in 8 cases survived. Venous congestion was observed in early postoperative period in only one case. But the flap survived completely after proper management in final healing. Follow-ups were made from 6 months and 12 months after operations. The color and texture of the flaps were similar to the adjacent skin in the forehead. The shapes were satisfying. Conclusions This kind of flap is a much better method for the repairing of some small or moderate defects in the forehead. It can be easily operated and allow a rapid aesthetic restoration.

Objective To investigate the roles of cell apoptosis and the gene expressions of Fas, FasL, bcl-2 and bax in acute rejection of pancreaticoduodenal transplantation and to evaluate the function of duodenum biopsy for early detection of rejection in rats. Methods Wistar and SD rats were divided into two groups: ①Wistar rats that underwent allogenic pancreaticoduodenal transplantation from the organs of SD rats; ②Wistar rats that received homogenic transplantation. The grafts were then harvested on day 3, 5 and 7 after the transplantation, and all graft samples were observed with HE staining and TUNEL was also used to detect apoptotic cells. The expressions of Fas, FasL, bcl-2 and bax were measured by immunochemical method. According to Nakhleh’s score, pathologic features of transplanted pancreas and duodenum were ranged from one to three scores in order. Results The percentage of same or different scores between the pathological scores of pancreas and duodenum in allogenic pancreaticoduodenal transplantation group were 61.1% (11/18) and 38.9% (7/18) respectively, and there were 6 specimens of pancreatic tissue got higher scores with only one higher score for duodenum. There were significant differences of histopathologic rejection scores and apoptotic indices between the two groups, respectively (P

[Objective] To develop a new type nerve tissue engineering scaffolds to repair the defect of peripheral nerve and observe the growth of bone marrow stromal cells cultured in vitro on the scaffolds.[Method]The biomaterial was made of I-collagen and gelatin by freeze-drying method,the alignment regularities of microscopic channels and there course directions were observed under the scanning electronic microscope.The size of the micropores and the factor of porosity were also measured.The bone marrow stromal cells were seeded on the collagen scaffolds and cultured for 5 days,then the growth of bone marrow stromal cells cultured in the scaffolds was observed.[Result]All the scaffolds were circular cylinder,the microscopic channels were arranged in parallel manners,and the pore sizes of the channels were uniform.The bone marrow stromal cells were seeded in the scaffolds successfully.[Conclusion]The developed nerve tissue engineering scaffolds have good structure and biocompatibility,which can be used in the repair of the nerve injuries.