1.Postoperative radiotherapy for high-grade gliomas
Journal of International Oncology 2011;38(1):27-29
Radiotherapy is one of the most important treatments for glioma; however its therapeutic effect is unsatisfying. Timing, accurate target outlining, a total dose higher than 60Gy, conformal modulating radiotherapy and combined chemotherapy and targeted therapy are important factors in improving the outcome of radiotherapy.
2.Applicationof opticalanalysis measurements to medical analysis instrument
Chinese Medical Equipment Journal 1989;0(01):-
This paper describes the basic principles of optical analysis measurements,such as colorimetry,spectrophotometry,fluorometry,fluorescence spectrophotometry and scatter,and their typical applications to medical analysis instrument.The quality control of the optical analysis instrument and their development are also discussed.
3.The use of nasointestinal tube feeding in patients receiving mechanical ventilation.
Hao LOU ; Tongwa CAO ;
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective To evaluate the effect of nasointestinal tube in patients receiving mechanical ventilation.Methods Patients receiving mechanical ventilation were randomLy divided into two groups.The two groups were isocaloric and isonitrogen.The study group used nasointestinal tube feeding.The control group used nasogastric tube feeding.Nutrition status,ventilator days,aspiration incidence and pneumonia incidence were measured.Results 178 patients receiving me- chanical ventilation were divided into two groups.The study group showed reduction in aspiration incidence and pneumoni- a incidence.Other measurements showed no significant difference.Conclusion Nasointestinal tube feeding could reduce aspiration and pneumonia incidence in patients receiving mechanical ventilation.
4.Evaluation of patient-ventilator synchrony of three new types of ventilators with pressure sunnort ventilation mode.
Juan ZHOU ; Hao WU ; Desen CAO
Journal of Biomedical Engineering 2014;31(4):793-797
Pressure-support ventilation (PSV) is a form of important ventilation mode. Patient-ventilator synchrony of pressure support ventilation can be divided into inspiration-triggered and expiration-triggered ones. Whether the ventilator can track the patient's inspiration and expiration very well or not is an important evaluating item of the performance of the ventilator. The ventilator should response to the patient's inspiration effort on time and deliver the air flow to the patient under various conditions, such as different patient's lung types and inspiration effort, etc. Similarly, the ventilator should be able to response to the patient's expiration action, and to decrease the patient lung's internal pressure rapidly. Using the Active Servo Lung (ASL5000) respiratory simulation system, we evaluated the spontaneous breathing of PSV mode on E5, Servo i and Evital XL. The following parameters, the delay time before flow to the patient starts once the trigger variable signaling the start of inspiration, the lowest inspiratory airway pressure generated prior to the initiation of PSV, etc. were measured.
Exhalation
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Humans
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Inhalation
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Interactive Ventilatory Support
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Lung
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physiology
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Pressure
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Ventilators, Mechanical
5.Combined NFC and RFID-based innovative service in library
Juan CAO ; Yanan HAO ; Caiyu LIU
Chinese Journal of Medical Library and Information Science 2015;(7):40-43
NFC is characterized by its short transfer distance, low energy consumption, multiple operation model, high safety, portability, good interconnection, and compatibility with RFID.It can thus be considered as the updated edition of RFID.The significance to innovate the service of library using combined NFC and RFID was therefore elaborated with some suggestions put forward for constructing the smart library.
6.Preparation and bioavailability of ibuprofen dispersible tablet in rabbits
Chunjie CAO ; Hao ZOU ; Xuetao JIANG ;
Academic Journal of Second Military Medical University 2000;0(10):-
Objective: To prepare ibuprofen dispersible tablet and compare its pharmacokinetics and bioavailability with market tablets in rabbits. Methods: According to inspection of factors and orthogonal design, optimal formulation was decided. A randomized crossover and self control design was used. Eight healthy rabbits were single oral dosed with 100 mg ibuprofen dispersible tablet or market tablet, respectively. The plasma drug concentration was determined by HPLC method. The pharmacokinetic parameters were calculated by 3P87 program and the bioequivalence was assessed by NDST5.0 program. Results: A one compartment open model was adopted and the pharmacokinetic parameters of dispersible tablet and market tablet were as follows: c max were (9.79?2.25) and (4.54?1.50) ?g/ml; t max were (0.27?0.07) and (2.03?0.53) h; t 1/2 were (6.65? 2.14) and (9.17?4.38) h; AUC 0~∞ were (94.11?28.38) and (65.20?18.38) ?g?h?ml -1 , respectively. Ralative bioavailability of the dispersible tablet was 164.11% compared to market tablet. Conclusion: Ibuprofen dispersible tablet is administrated easily and absorbed quickly, and its bioavailability is far more better than the market one. [
7.Construction of academic native resource repository platform
Xia WANG ; Hongxin CAO ; Hao CHEN
Chinese Journal of Medical Library and Information Science 2015;(8):55-58
After the importance to construct academic native resource repository platform was elaborated,the native resource repository platform designed and constructed by Library of Second Military Medical University according to the demands of Second Military Medical University was described, which improved the management efficiency of scientific research and academic achievements.
8.Updated biological characterization of Th17 cells
Hao CAO ; Huimin FAN ; Zhongmin LIU
Journal of Medical Postgraduates 2003;0(11):-
Th17 cells play an important role in the pathogenesis of various immune-mediated diseases,including psoriasis,rheumatoid arthritis,multiple sclerosis,inflammatory bowel disease,asthma,and so on.The discovery of Th17 cells has offered scientists a new insight into the etiology and treatment of a broad spectrum of diseases.This article presents an overview of the differentiation,cytokine expression and trafficking of Th17 cells.
9.Histological research of calcium phosphate biomaterials promoting tendon healing in bone tunnels
Hao SHEN ; Hongbin CAO ; Yao JIANG
Chinese Journal of Orthopaedic Trauma 2004;0(11):-
Objective To investigate the effect of osteoinductive calcium phosphate ceramics (OICPC) on tendon healing in bone tunnels. Methods Anterior cruciate ligament reconstruction with semitendonous tendon was performed in the knee joints of 30 New Zealand rabbits by suspended fixation. OICPC grains were implanted into the bone tunnel of 15 rabbits which were the experimental group and the other 15 rabbits without OICPC implants severed as the control group. Specimens were collected four weeks, eight weeks and 12 weeks after surgery. Sections were stained with H. E., Sirius Red and Masson. Histological changes in the interface tissue between the bone tunnel and the tendon graft were observed, and the morphology of interface tissue was classified according to Yamakado method. Histomorphometry was done on Masson stain sections to measure new bone formation around the grafted tendon. Results In OICPC group, histological sections obtained four and eight weeks after surgery showed statistically greater new bone formation than those in the control group. Abundant penetrating Sharpey fibers appeared at eight weeks and direct connection was found at 12 weeks in the experimental group. On the other hand, Sharpey fibers appeared only at 12 weeks in the control group. Conclusion OICPC has a capability of enhancing biological fixation of a tendon to the bone tunnel.
10.Change of cognitive function and cerebral blood flow in patients with transient ischemic attack
Xinrong XIE ; Ying CAO ; Shuliang HAO
Journal of Clinical Neurology 1995;0(04):-
Objective To investigate the change of cognitive function and cerebral blood flow in patients with transient ischemic attack(TIA).Methods 35 patients with TIA and 33 normal controls who matched in sex, age, right handed and education were tested by events related potential(ERP), the scale of elderly cognitive function(SECF) and magnetic resonance angiography(MRA).Results The peak latencies of P 3 components of ERP in the patients were significantly delayed as compared with the control group( P