1.Surgical treatment of inguinal hernia recurrence with prolene hernia system
Chinese Journal of Primary Medicine and Pharmacy 2009;16(3):398-399
Objective To summarize the experiences of tension-free method in inguinal hernia recurrence.Methods Using the PHS Ethicon Ine,42 patients with recurrent hernia were performed tension-free hemioptasty.Results The operation time was from 40 to 150 minutes.The patients could walk up within 1 d after the procedure.No incision infection was found.The eomplicatiom included 4 retention of urine.3 large serotal hematoma requiring surgical drainage.The follow-up period ranged from 6 months to 3 years,no recurrence and foreign body sensation in inguinal region were observed.Conclusion PHS call be anatomically adapted to repairing and augmenting the myopectineal orifice.It is suitable to the patients with recurrent inguinal hernia.
2.Assay of Compound Alcoholic Solution of Benzoic Acid by Linear Combination Method of Absorbances
China Pharmacy 1991;0(02):-
We adopted the linear combination method of absorbances to assay the contents of compound alcoholic solution of benzoic acid directly without isolation of its components. The recovery rates of benzoic acid and salicylic acid were 100.97% (cv=0.86%)and 100.29%(cv=0.82%)respectively.
3.Preparation and Content Determination of Lincomycin Hydrochloride Glycerol Paint
Hanlin LIU ; Ping HU ; Jiafu ZHOU
China Pharmacy 2005;0(13):-
OBJECTIVE: To prepare lincomycin hydrochloride glycerol paint and to determine its content. METHODS: Lincomycin hydrochloride glycerol paint was prepared using lincomycin hydrochloride and dyclonine hydrochlorideas as main components; the contents of the two main components were determined by HPLC. RESULTS: The linear ranges of lincomycin hydrochloride and dyclonine hydrochloride were 20~200 ?g?mL-1(r=0.999 8) and 10~100 ?g?mL-1(r=0.999 9),respectively. The average recoveries(n=5) were 99.61% and 99.28%,with RSD stood at 0.439% and 0.818%,respectively. CONCLUSION: Both the preparative method and determination method for lincomycin hydrochloride glycerol paint are simple and feasible.
4.Relationship of CACNA1C gene polymorphism with schizophrenia
Hanlin HONG ; Xiurong DUAN ; Chanyuan LIU
Chinese Journal of Nervous and Mental Diseases 2016;42(4):199-205
Objective To examine the relationship of calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNAIC) gene polymorphism with schizophrenia. Method A total of 118 patients with schizophrenia and 122 healthy volunteers were selected in succession. Denaturing high performance liquid chromatography (DHPLC) was used to analyze the genotypes of CACNAIC gene (rs10848683, rs2238032 and rs2299661). Medical record data of patients with schizophre?nia and the clinical manifestation of the patients (sensation and perception disorder, thought disorder, affective disorder and behavior disorder) were collected. The clinical phenotype databases of all patients were established. Result There were statistical differences for genotype and allele distribution of the rs2238032 and rs2299661 between patient group and control group (P<0.05). The TT genotype of rs2238032 (OR=0.394) and the CG genotype of rs2299661 (OR=0.326) associ?ated with the risk of schizophrenia. The genotype distribution of rs2238032 was related to the thought disorder, the emotion disorder and the PANSS score of schizophrenia patients (all P<0.05). The genotype distribution of rs2299661 was related to the perceptual disorders and PANSS score of schizophrenia patients (all P<0.05). Haplotype analysis showed that CTC (OR=1.811), CTG (OR=0.432) and TGC (OR=1.771) were significantly associated with schizophrenia (P<0.05). Conclu?sion The CACNA1C gene polymorphism is associated with schizophrenia and its clinical manifestations.
5.Vinorelbine and Nedaplatin Regimen in Treatment of Advanced Non-small Cell lung Cancer
Yongzhong LIU ; Jiewen PENG ; Zhaofeng YIN ; Hanlin LIANG
Journal of Medical Research 2006;0(06):-
0.05).Conclusion There is no significant difference of short-term effect between the two groups in treating advanced NSCLC,and the method has mild digestive reactions and nephrotoxicity.
7.Relationship Between Tongue Manifestations and Immune Function in Chronic Hepatitis B with HBsAg, HBeAg and HBcAb Positive
Xiaoyan ZHOU ; Hanlin ZHONG ; Huixian WEN ; Futai YANG ; Hongjian LIU
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(01):-
[ Objective ] To investigate the relationship between tongue manifestations and immune function in chronic hepatitis B with HBsAg, HBeAg and HBcAb positive. [Methods] Among the cases of HBsAg, HBeAg and HBcAb positive from the out - patient department and health screening survey, 200 chronic hepatitis patients and 100 asymptomatic HBV carriers with glumatic - pyruvic transaminase at normal level were included. Thirty healthy volunteers served as control. Relationship of tongue manifestations with phytohemagglutinin (PHA) skin test and the serum levels of immunoglobulin (Ig) G, IgA and IgM was analyzed. [Results] With the development of chronic hepatitis, the immune function became disordered and tongue manifestations abnormal. Reddish tongue with or without yellowish greasy fur or yellowish fur showed the hyperactivity of immune function; whitish swollen tongue with or without whitish greasy fur indicated the hypoactivity of immune function; dull purplish tongue was the sign of disordered immune function. The shape and color of tongue was superior to tongue fur in showing the condition of immune function ( P
8.Treatment of femur fracture in neonates using harness
Yuchang LIU ; Weifeng LIN ; Zhenwu YU ; Yazhou LI ; Hanlin WANG
Chinese Journal of Postgraduates of Medicine 2008;31(9):13-16
Objective To treat femur fracture in neonates using a new homemade harness designed and observe the effec of this harness. Methods Designed a new harness used in femur fracture in neonates,and used this harness in 7(8 femur fracture)csses,including 6 boys(7 femur fracture)and 1 girl,the age from 1 day to 12 days(average 4.7 days).Those cases included proximal thirds(2 cases)and middle thirds(6 cases)of femur fracture.The angle of fracture was from 44°to 83°(average 62.4°)before treatment. Results The angle of fracture was from 0°to 22°(average 14.0°)after treatment using the harness.Hespitalization was from 2 to 3 days.There were no skin sloughing or harness breaking off.All cases were followed up 6 to 36 months(average 21.3 months).All femur fracture healed in good alignment with leg-length discrepancy<1 cm.Movement of hip and knee was normal. Conclusions The harness is a better method to treat femur fracture of the proximal and middle thirds in neonates.Advantages of it include simply operation,minimal hospitalization,minimal cost,and easy nursing.
9.Determination of 3 Kinds of Components in Compound Xueyaan Sustained Release Tablets by HPLC
Xianling SHEN ; Feng XIAO ; Hanlin LIU ; Changfu WU
China Pharmacy 2007;0(25):-
OBJECTIVE: To establish HPLC method for the determination of the contents of atenolol, hydrochlorothiazide and nifedipine in xueyaan sustained release tablets. METHODS: The determination was performed on ZORBAX SB C18 column with column temperature at 35℃ . The mobile phase consisted of 0. 01mol? L- 1 sodium dihydrogen phosphate solution- methanol- acetonitrile ( 6∶ 3∶ 1) . The UV detection wavelength was set at 272nm and the sample size was 20? L. RESULTS: The liner ranges of atenolol, hydrochlorothiazide and nifedipine were 10~ 250? g? mL- 1 ( r=0. 999 4) , 6~ 150? g? mL- 1( r=0. 999 6) , and 5~ 125? g? mL- 1( r=0. 999 2) respectively. The average recovery rates of the three constituents were ( 98. 51? 0. 98) % ~ ( 99. 12? 0. 98) % , ( 98. 87? 1. 10) % ~ ( 99. 69? 1. 43) % , and( 98. 80? 1. 27) % ~ ( 99. 38? 1. 13) % , respectively, with RSD at 1. 00% , 1. 17% , and 1. 25% , respectively. CONCLUSION: The established method is simple, sensitive and reproducible, and suitable for the quality control of xueyaan sustained release tablets.