1.The rate of secondary injuries in stroke patients at acute phase
Hue Thi Nguyen ; Hanh Thi Bich Vu
Journal of Medical Research 2008;54(2):63-67
Background: Secondary injuries are frequent in stroke patients at the acute phase. The early rehabilitation for these patients currently still hasn't received enough attention. Thus it may increase the rate of the secondary disorders. Objectives: To describe the common secondary injuries in stroke patients at the acute phase. Subjects: 90 stroke patients over 18 years old that had experienced hemiplegia less than 30 days, and were treated at Neurology Department, Bach Mai Hospital. Method: Cross-sectional study. Data was analyzed by SPSS software, version 13.0. Results: The rate of the secondary injuries in these patients had reached 80.0%. Among them, the rate of pneumonia is the highest with 30.0%, then urological infections with 17.8%, followed by muscular atrophies, contracture of muscles, stress ulcer, and orthostatic hypotension. There is a close relation between pneumonia and perception impairment: the rate of pneumonia in perception impairment patients was 5.25 folds higher than that in patients without perception impairment (67.9% vs. 12.9%, p< 0.001). Similarly, pneumonia rate in patients with nasogastric tube was 4.2 folds higher than that of patients without nasogastric tube (90.9% vs. 21.5%, p< 0.001). Conclusion: The rate of the secondary injuries in acute stroke patients is high. It is necessary to carry out intensive nursing and rehabilitation for these patients.
secondary injuries
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stroke
2.Within-household SARS-CoV-2 transmission and vaccine effectiveness in the first three COVID-19 school outbreaks in northern Viet Nam, September–December 2021
Trang Thu Vu ; Tu Huy Ngo ; Khanh Cong Nguyen ; Vu Thi Lan ; Cu Thi Bich Hanh ; Le Hong Son ; Huyen Thi Nguyen ; Hien Thi Nguyen ; Nghia Duy Ngu ; Duong Nhu Tran ; Duc-Anh Dang ; Florian Vogt ; Thai Quang Pham
Western Pacific Surveillance and Response 2024;15(3):19-30
Objective: The risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from schoolchildren to their household and the protective effects of vaccination in these settings remain poorly understood. We assessed the transmission dynamics of schoolchildren with SARS-CoV-2 within their households and the protective effects of coronavirus disease (COVID-19) vaccination among household members in Viet Nam.
Methods: We estimated the attack rate, vaccine effectiveness and adjusted risk ratio (aRR) of factors associated with SARS-CoV-2 transmission to household contacts of children confirmed to have COVID-19 who attended three schools in Ha Nam, Phu Tho and Thanh Hoa provinces between September and December 2021 using multivariable regression with household-level random effects.
Results: This retrospective cohort study included 157 children infected with SARS-CoV-2 and their 540 household contacts. The attack rate among household contacts was 24.6% (133/540). Overall, vaccine effectiveness among household contacts was 39% (95% confidence interval [CI]: -1 to -63), higher among males than females and higher in adults aged >40 years. COVID-19 transmission was greater among female household contacts compared with males (aRR: 1.35, 95% CI: 0.94 to 1.95), although not statistically significant, and highest among those aged 19–39 years (aRR: 2.51, 95% CI: 1.50 to 4.21). Fully vaccinated household contacts had significantly lower infection risk (aRR: 0.46, 95% CI: 0.26 to 0.84).
Discussion: We found substantial onward transmission of SARS-CoV-2 from schoolchildren to household members, and older people were more likely to be protected by vaccination. We recommend that schoolchildren and all household members living with schoolchildren receive at least two doses of a COVID-19 vaccine. Recognizing the role of schoolchildren in the onward transmission of COVID-19 is an important lesson learned by Viet Nam that can help not only in managing other outbreaks but also in protecting schoolchildren by predicting the progress of the outbreak and preparing for a timely response.