Objective To summarize the application of the Cable Plate System in the treatment of periprosthetic femur fracture after hip replacement. Methods The clinical data and image records of 11 patients who underwent reduction and fixation by means of the Cable Plate System from 1998 to 2002 were retrospectively analyzed. The follow-up and X-ray results at different times after operation were evaluated. Results Out of the 11 cases, non-deforming union and stable prosthesis were obtained in 8 cases, non-deforming union and slight subsidence of prosthesis in 2 cases, and, a broken plate and varus malunion occurred in 1 case, in which a second operation was required. Conclusions The Cable Plate System is one of the effective methods in the treatment of periprosthetic femur fracture after hip replacement.