1.Recommended allowance for dietary fiber in childhood
International Journal of Pediatrics 2014;41(3):292-294
The essential nutrients include carbohydrate,protein,lipids,minerals,vitamins and water.Recently,dietary fiber has been listed as an essential component for nutrition and health.Dietary fiber plays an important role on the health of children,such as reducing constipation,preventing overweight and obesity,etc.This article reviews recent progress in research of the recommended allowance for dietary fiber in childhood.
2.Clinical curative effect of pendant laparoscopic uterine fibroids divest and factor analysis of recurrence
Chinese Journal of Postgraduates of Medicine 2014;37(18):21-23
Objective To compare the chnical curative effect between pendant laparoscopic and traditional laparoscopic apphed in uterine fibroids divest,and analyze the risk factors of recurrence after resection of uterine fibrnids.Methods According to the different methods,130 patients with uterine fibroids were divided into suspension group (pendant laparoscopic uterine fibroids divest) and control group (traditional laparoscopic uterine fibroids divest),and 65 cases in each group.The intraoperative blood loss,operative time,exhaust time,heating duration,laparoscopic drainage were recorded,and the complications and the factors of recurrence were evaluated.Results The operative time,intraoperative blood loss,laparoscopic drainage in suspension group was less than that in control group [(53.5 ±20.9) min vs.(100.8 ± 26.7) min,(92.7 ± 18.9) ml vs.(168.4 ± 19.6) ml,(94.3 ± 13.8) ml vs.(186.5 ± 24.7) ml],the complications rate in suspension group was lower than that in control group [3.08% (2/65) vs.33.85% (22/65)],and there was significant difference (P < 0.05).Followed up for 1-3 years,the recurrence rate was 29.23% (38/130),3 cases were recurred within 3-6 months in control group,no recent recurrence in suspension group.Among them,the menarche age ≤13 years old,multiple myoma,operation age < 35 years old were correlated with recurrence (P< 0.01 or < 0.05).Conclusions Pendant laparoscopic uterine fibroids divest is fast and safe in operation and the prognosis effect significantly,faint pain degrees,myoma resection completely,short hospitalization period,less postoperative recurrence and other advantages,is worthy of reference for clinical promotion.The menarehe age ≤ 13 years old,multiple myoma,operation age < 35 years old are correlated with recurrence.
3.Functions of The 3′ Untranslated Region of Eukaryotic mRNA
Haizhen WANG ; Ying WANG ; Dinggan LIU
Progress in Biochemistry and Biophysics 2006;0(09):-
Functions of the 3′untranslated regions (3′UTR) of eukaryotic mRNAs are complicated. They can control the stability and intracellular localization of mRNAs, and direct the translation of special amino acids. Mutations in the 3′UTR of some mRNA can cause serious diseases, and recent studies showed that the 3′UTR of some eukaryotic mRNAs possess tumor-suppression function.
4.Application research of free connective tissue transplantation with periosteum in immediate implant and immediate prosthesis in aesthetic area
Haizhen WU ; Xin WANG ; Shengjie WANG
Chongqing Medicine 2014;(18):2285-2287,2290
Objective To evaluate the clinical aesthetic effect of immediate implant and immediate prosthesis by the free connec-tive tissue transplantation with periosteum in the maxillary anterior region.Methods 65 appropriate patients were selected and per-formed the immediate implant after minimally invasive tooth extraction.6 5 pieces of implants were implanted immediately by the free connective tissue transplantation with periosteum in the aesthetic area,among them,10 cases were implanted by Bio-oss bone. All missing teeth were immediately repaired by temporary denture,after the implant osseointegration,the permanent repair was per-formed.From the preoperation to 1 8 months after permanent repair,the aesthetic evaluation was conducted by stages,including the labial peri-implant soft tissue fullness and pink aesthetic scores(PES).Results In the tracing assessment period,the peri-implant fullness evaluation showed that degree 0 was found in 5 tooth positions before the operation,degree Ⅰin 60 tooth positions,degreeⅡ in 0 tooth position,but after immediate restoration,degree 0 in 0 tooth position,degree Ⅰin 45 tooth positions and degree Ⅱ in 20 positions.The PES total value reached the maximum in 3 months after permanent restoration.Conclusion Immediate implant and immediate prosthesis by the free connective tissue transplantation with periosteum in the maxillary aesthetic area can obtain better aesthetic results.
5.Clinical festures and CLCN1 gene mutation screen on a myotonia congenital kindred
Haizhen WANG ; Zengfu LI ; Hong ZHENG
Journal of Clinical Neurology 1993;0(03):-
Objective To investigate the clinical festures and CLCN1 gene mutation screen on a myotonia congenital kindred.Methods The clinical data of 22 patients in the myotonia congenital kindred were analysed. Results There were total 68 people in 5 generations, including 24 patients in 4 generations .Both male and female were suffered. All patientes of this kindred showed myotonia with onset the illness from the infant, and 16 cases accompanied with hypermyotrophy.The levels of creatases and dielectric in serum were normal in all the cases. Spontaneous myotonic electric potential were observed on electromyography( EMG ) in 2 cases.The proband was found in light microscope by biopsy that muscle fibers arranged loosenly , size of them mismatched , transverse striation was unclear and some of them was hyperplasia and hypertrophy. Muscle cells degenerated gently with a few inflammatory cells infiltration. No mutation was found in the whole 23 extrons of CLCN1 gene in the 3 patients.Conclusions This kindred accords with the autosomal dominant heredity form Thomsen's disease. The affected numbers have the typical clinical characteristics. No mutation is found when 23 extrons of CLCN1 gene screened in the patients which indicate the genetic heterogeneity may be exist in this kindred.
6.Effect of oxalipatin combined with S-1 on related protein expression in advanced gastric cancer
Haizhen WANG ; Xia LI ; Xinfang SHAN ; Yanhai LI ; Jieshu WANG
Chinese Journal of Primary Medicine and Pharmacy 2016;23(6):814-817
Objective To analyze the clinical effect of neoadjuvant chemotherapy( oxaliplatin combined with S-1) in the treatment of advanced gastric cancer,and to detect its influence on expressions of vascular endothelial growth factor(VEGF) and matrix metalloproteinase-2(MMP-2).Methods A total of 70 patients with advanced gastric cancer were randomly divided into research group ( n=35 ) and control group ( n=35 ) .The patients in the control group were given surgery treatment and general drug chemotherapy,while the patients in the research group were given the neoadjuvant chemotherapy on the basis of the control group.The incidence of cancer recurrence and the expressions of MMP-2,VEGF of the two groups were observed.Results In the research group,the expressions of MMP-2 or VEGF were significantly different before and after chemotherapy(χ2 =10.03,χ2 =9.11,all P<0.01). The 3-year survival rate in the research group(71.43%) was significantly higher than 45.71% in the control group,there was significant difference(χ2 =11.70,P<0.05).Conclusion Neoadjuvant chemotherapy can reduce the expressions of MMP-2 and VEGF in tumor tissues,indicates that it may play an important role in patients with advanced gastric cancer and can be used in clinic.
7.Efficacy of budesonide/formoterol powder for inhalation in treatment of patients with bronchial asthma
Haizhen JIN ; Jiyang ZHENG ; Xinjian DAI ; Qiong CHI ; Wantie WANG
Chinese Journal of Biochemical Pharmaceutics 2015;(12):100-101
Objective To observe the clinical effect of therapy of budesonide/formoterol powder for inhalation in treatment of adult with bronchial asthma.Methods 90 cases with bronchial asthma and were divided into observation group and control group randomly from February 2014 to February 2015.45 cases in each group.Control group was treated with budesonide inhalants +formoterol inhalants, observation group was given budesonide/formoterol powder inhalation.Changes of related indicators were followed up and recorded.Results After treatment, IL-5, IL-12 and IFN-γwere (60.2 ±9.7)pg/mL,(31.4 ±3.1)pg/mL,(1.6 ±0.2) ng/mL of observation group were better than control group (72.8 ±10.7)pg/mL,(38.5 ± 5.6)pg/mL,(2.3 ±0.3) ng/mL (P<0.05).After treatment,total effective rate in observation group was 68.9%, which was better than control group (48.9%)(P<0.05).Conclusion Clinical effect of budesonide/formoterol powder for inhalation in treatment of patients with bronchial asthma is accurate, and there is no obvious adverse reaction.
8.Influence of negative emotions on prognosis of patients with coronary heart disease undergoing PCI
Haizhen WANG ; Qing JIANG ; Wanshi WU ; Guodong LIU
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(2):130-133
Objective:To explore influence of negative emotions on prognosis of patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI) .Methods :Self‐rating anxiety scale (SAS) and self‐rating depression scale (SDS) were used to assess 90 patients undergoing PCI .According to the score results ,patients were divided into pure depression group (n=28 ,occupied 31.11% ) ,pure anxiety group (n=22 ,24.44% ) ,anxiety com‐plicated depression group (n= 25 ,27.78% ) and normal group (n = 15 ) . All patients were followed up for 12 months ,and Logistic regression analysis was used to analyze risk factors for major adverse cardiovascular events (MACE) .Results:Incidence rates of MACE in pure depression group ,pure anxiety group and anxiety complicated depression group were significantly higher than that of normal group (42.86% vs .40.91% vs .64.00% vs .6.67% , P<0.05 or <0.01) ,and that of anxiety complicated depression group was significantly higher than those of pure depression group and pure anxiety group (P<0.05 both) .Logistic regression analysis indicated that anxiety ,depres‐sion ,anxiety complicated depression were risk factors for MACE (OR = 1.49 ,2.16 ,3.28 , P < 0.05 or < 0.01) . Conclusion : Most patients undergoing coronary intervention possesses negative emotions ,which are risk factors for adverse clinical events and affect their prognosis .
9.curative effect and nursing of medical ozone autohemotherapy in clinical treatment
Haizhen ZENG ; Aiqin YE ; Qun WANG ; Limei ZANG
Chinese Journal of Practical Nursing 2016;32(z1):8-9
Objective To investigate the curative effect and nursing of medical ozone autohemotherapy in clinical treatment. Methods 45 cases of cerebral infarction patients with medical ozone self blood therapy spells, psychological guidance and health education before operation in the sterile operation, postoperative nursing, education results. Results 45 cases of cerebral infarction in patients with very good completed treatment, 2 cases because of dizziness aggravated, 2 cases of vascular puncture for difficult to stop treatment, the rest were different extent achieved certain effect. Conclusions the clinical experiment showed that the nursing, preoperative education, psychological guidance and sterile operation, postoperative is an effective measure for ensuring medical ozone autohemotherapy smooth finish.
10.Factors and countermeasures about the quality of adult medical education
Jiaming GOU ; Yingji YUAN ; Jian FENG ; Haizhen WANG
Chinese Journal of Medical Education Research 2011;10(11):1370-1372
Adult medical education has its own particularity.Its quality is affected by students' work units,families,schools,their own and other factors.Changing concepts,optimizing management,promoting personal quality education,setting up early warning mechanism,and doing full co-ordination are effective ways to improve the quality of adult medical education.