1.Analysis of the Resources Construction Mode of the National Scientific Data Sharing Platform for Population and Health
Journal of Medical Informatics 2015;(10):72-76
The paper summarizes features of the resources construction mode of the national scientific data sharing platform for popu -lation and health and analyzes main problems existing in the management , standardization and normalization of platform resources con-struction.On this basis, it proposes thinking and suggestion , and points out that a complete mechanism for resources assessment and ac-cess should be formed as soon as possible for the platform , the work progress of standardization should be promoted positively and the awareness of opening and sharing scientific data should be strengthened .
2.MSCT noninvasive imaging evaluation of the correlation between periodontal bone loss and carotid calcifications
Jinghua SUN ; Haixia LIU ; Shuquan ZHANG
Journal of Practical Radiology 2016;32(10):1517-1519
Objective To detect the correlation between the periodontal bone loss and carotid calcifications by using MSCT.Methods Imaging materials of 270 patients who were suspected atherosclerosis and underwent MSCT were retrospectively studied.According to the score of carotid calcification,the patients were divided into three groups:slight calcification group (carotid calcification score <100),severe calcification group (carotid calcification score ≥100),and normal control group (carotid calcification score=0).The original images were post-processed with volume rendering(VR),multi planar reformation(MPR),curved planar reformation(CPR)and maximum intensity projection (MIP)by using EBW4.5 workstation,and then the residual teeth number and the periodontal bone loss teeth were recorded in different groups.Results On MSCT,the carotid calcification score and the number of periodontal bone loss were displayed clearly.The number of the periodontal bone loss teeth in the calcification groups were significantly higher than those in the normal control group(P<0.01).Furthermore,the number of the periodontal bone loss teeth was positively correlated with the severity of carotid calcification.Conclusion The periodontal bone loss is highly correlated with the severity of the carotid calcification.The volume reconstruction technique of MSCT is a non-invasive diagnostic testing to detect the periodontal desease and to quantify carotid calcifications.
3.Advances on Pharmacological Effects of Monkshood Polysaccharide
Haixia XIONG ; Ying YANG ; Wenyan SUN
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(9):1948-1951
Aconite roots are a common clinical poisonous herb in Chinese herb. It has the effect of restoring yang and rescuing collapse, supplementing fire and assisting yang, eliminating cold and relieving pain. It is used in the treatment of yang collapse and yang deficiency syndromes. It is called principle medicine of all medicines. Monks-hood polysaccharide is one of effective components in Aconite roots. The study found that monkshood polysaccharide has effects of immune regulation, antitumor, myocardial preservation, lipid lowering, etc.
4.Effects of Bu Sui Sheng Xue Instant Granules on Expression of Serum Soluble Fas, TNF -a and IL - 2 in the Patient of Chronic Aplastic Anemia
Weizheng SUN ; Haihong LUO ; Haixia LI
Journal of Traditional Chinese Medicine 1992;0(09):-
In order to approach the mechanisms of Chinese drug Bu Sui Sheng Xue Instant Granules for tonifying kidney inhibiting apoptosis in the patient of chronic aplastic anemia (CAA), levels of soluble Fas (sFas), tumor necrosis factor (TNF-a), interleukin - 2 (IL - 2) before and after treatment were determined in 30 cases of CAA and Zai Zang Sheng Xue Tablet was used as control. Results indicated that expression of serum sFas, TNF - a and IL - 2 before treatment was significantly higher than those of the control group (P0. 05), and the IL-2 level still was higher than the normal (P
5.Use of partial cardiopulmonary bypass for surgery of descending thoracic aneurysm
Jianhua LIU ; Haixia LIU ; Jianquan SUN
Chinese Journal of Primary Medicine and Pharmacy 2008;15(5):777-778
Objective To summarize the experience of use of partial cardiopulmonary bypass for surgery of descending thoracic aneurysm. Methods Thirty five patients were undertaken surgery of descending thoracic aneurysm using partial cardiopulmonary bypass and beating-heart technique in our hospital. The partial cardiopulmonary bypass includes left heart bypass (left atrial to femoral artery bypass), pulmonary artery to femoral artery bypass, femoral vein to femoral artery bypass. Results Only one patient died, the other thirty four patients experienced an uneventful recovery. There was no any complication related to partial cardiopulmonary bypass. Conclusion The use of partial cardiopulmonary bypass for surgery of descending thoracic aneurysm can reduce and avoid the complications of nervous system and urinary system effectively.
6.Investigation and analysis of status of research and research utilization in practice among nurses of hospital of Traditional Chinese Medicine
Hua ZHANG ; Guihua XU ; Zhiling SUN ; Haixia GAO ; Yinfeng DONG
Chinese Journal of Practical Nursing 2014;30(27):42-45
Objective To investigate the status of research and research utilization in practice among nurses of hospital of Traditional Chinese Medicine.Methods Two hundred and sixty nurses of hospital of Traditional Chinese Medicine were selected to fill out the questionnaire.Results The rates of involvement of research activities and research utilization among nurses of hospital of Traditional Chinese Medicine were low.The score of every factor ranged from the higher to the lower were communication,organization,research and nurse.Conclusions Involvements of research activities and research utilization among nurses of hospital of Traditional Chinese Medicine are insufficient.Most factors associated with nurses' low extent of research utilization are objective factors.It is pivotal for nursing managers to construct supportive professional environment,improve nurses' research and information skills and the capacity of the research utilization.
7.An assessment of labial bone mass after immediate implant or delayed implant placement in esthetic zone
Wei FENG ; Shufeng WANG ; Jinyou GENG ; Yuanyuan SUN ; Haixia GENG
Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(4):283-286
Objective To evaluate the alteration of labial bone mass one year after immediate implant or delayed implant placement in esthetic zone.Methods From June 2009 to June 2012,22 patients with 11 immediate implant and 11 delayed implant in the maxillary anterior region were followed up.CBCT images were obtained immediately after surgery and one year after implant placement,the horizontal and vertical alterations of the labial bone were evaluated by image analysis software.Results The 1-year vertical reduction of labial bone after immediate implant placement was statistically significant (P<0.05),and no significant difference in delayed implant (P>0.05).The 1-year horizontal reduction of labial bone was statistically significant at coronal and middle of implant,without significant difference at apical of implant.Conclusions Immediate implant can not stop the physical absorption of labial alveolar ridge,and the study can provide reference to achieve esthetics in the anterior region.
8.Importance of aneuploidy screening in preimplantation genetic diagnosis for the couples of chromosome translocation carriers
Gang LI ; Yingpu SUN ; Haixia JIN ; Zhimin XIN ; Shanjun DAI
Chinese Journal of Obstetrics and Gynecology 2011;46(1):32-35
Objective To determine the importance of aneuploidy screening in preimplantation genetic diagnosis for the couples of chromosome translocation carriers. Methods To perform 11 prenatal genetic disgnosis (PGD) cycles for 7 couples of chromosome translocation carriers from January 2006 to March 2009 in the Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University. To re-analyze the well-fixed, non-multinuclear and non-debris nuclei using the probes of LSI 13, 18, 21,CEPX, CEPY to detect the aneuploidy rate which come from the PGD cycles of the couples of chromosome translocation carriers. The euploid embryo was defined as two fluorescence in situ hybridization (FISH)signals of LSI 13, 18, 21 respectively and two signals of CEPX, or one signal of CEPX and one signal of CEPY. The other abnormal signals were defined as aneuploid embryo. Results (1) A tolal of 130 nuclei from 11 PGD cycles got the integrated re-FISH signals. Nine hundred and thirty-seven FISH signals were analysized, including 304 signals from 38 euploid nuclei and the others from 92 aneuploid nuclei. (2) The number of the aneuploid nuclei from grade Ⅰ , Ⅱ and Ⅲ embryo was 20 (22%), 36(39%), and 36(39%). The number of the euploid nuclei from grade Ⅰ , Ⅱ and Ⅲ embryo was 13(34%), 17(45%),and 8(21%). There was no significant difference of aneupioidy rate between the embryos form different grades (P>0.05). However, the rate of aneuploid nucleus from good quality embryos (grade Ⅰ + grade Ⅱ) was 60% (59/92). (3) The euploidy rate was 71.4% (30/42) from balanced embryos, while 9.1%(8/88)from unbalanced embryos. There was significant difference between them (x2=53.4, P<0.05).The rate of aneuploidy from balanced embryos was lower than those from unbalanced embryos (P<0.05).Conclusions Since higher rate of aneuploidy was detected in embryos of the couples of chromosome translocation carriers. It is advisable to recommend the FISH re-analysis for aneuploidy screening to preimplantation genetic diagnosis for the couples of chromosome translocation carriers.
9.Application of sperm fluorescence in situ hybridization in preimplantation genetic diagnosis
Gang LI ; Yingpu SUN ; Haixia JIN ; Zhimin XIN ; Shanjun DAI
Chinese Journal of Obstetrics and Gynecology 2009;44(6):418-421
genetic screening offered prior to preimplantation genetic diagnosis.
10.The correlation between periodontal diseases and carotid arteries atherosclerosis by three-dimensional reconstruction technique of multi-slice spiral CT in elderly people
Jin WANG ; Haixia LIU ; Jinghua SUN ; Yingjie FU
Chinese Journal of Geriatrics 2013;(1):25-27
Objective To explore the possible correlation between periodontal disease and carotid arteries atherosclerosis in old people,and to study the diagnostic value for periodontal disease using three-dimensional (3D) reconstruction technique of multi-slice spiral CT (MSCT).Methods Patients underwent multi-detector row CT angiography with carotid arteries atherosclerosis (control group) and without carotid arteries atherosclerosis (case group) were evaluated with the stereoscopic configuration of teeth,and the number of decayed teeth and lost teeth were recorded.Results Bythe 3D reconstruction technique,the number of decayed teeth and lost teeth between two groups were significantly different (P<0.05).The number of dental integrity patients was higher in control group (19 cases) than in case group(7 cases).The mean of dental caries was higher in control group(7.3±3.0) than in case group(6.0±2.1).The mean of hypodontia was higher in control group(45 cases) than in case group(39 cases) (P<0.05).Conclusions The 3D reconstruction technique of MSCT is a new method to display the stereoscopic configuration of teeth.The periodontal disease is significantly related with carotid arteries atherosclerosis in old people.