1.Radical Resection of Primary Leiomyosarcoma of Inferior Vena Cava
Ikhwan Sani MOHAMAD ; Sivabalan NADARAJAN ; Zamri ZUHDI ; Azim IDRIS ; Hairol OTHMAN ; Affirul CHAIRIL ; Razman JARMIN
Malaysian Journal of Medicine and Health Sciences 2018;14(1):61-64
Leiomyosarcoma of the Inferior Vena Cava (IVC) is a rare soft tissue tumour which accounts for only 0.5% of all soft tissue sarcomas. The patients usually presented with non specific clinical signs and often diagnosed at advanced stage. We reported a case of a 58-year-old lady who presented with right sided abdominal pain for 6 months. CT scan showed large Level 2 IVC tumour which encased the right renal vein and had no clear plane of demarcation with the caudate lobe of the liver. She underwent radical resection of the IVC tumour with the right kidney removed en bloc. Vascular reconstruction was not performed as established collateral veins present. She was nursed in Intensive Care Unit for 2 days and discharged well at day 5 post operatively. Histopathological examination results revealed leiomyosarcoma of IVC.
2.Comparison of Contrast Sensitivity and Central Corneal Thickness in Primary Open Angle Glaucoma Suspects and Visually Normal Participants
Siti Khadijah Osman @Othman ; Thayanithi Sandragasu ; Mohd Izzuddin Hairol
Malaysian Journal of Medicine and Health Sciences 2023;19(No.2):112-118
Introduction: Glaucoma causes a reduction of contrast sensitivity (CS) while thinner central corneal thickness is
(CCT) associated with the risk of glaucoma. Thus, in glaucoma suspect patients, CS and CCT measurements may
better evaluate and monitor the disease. The purpose of this study was to compare CS and CCT between a Primary
Open Angle Glaucoma (POAG) suspect group and a normal group of similar age. Methods: CS was measured with
the Pelli-Robson CS chart, while CCT was measured with a hand-held pachymeter. In total, 115 glaucoma suspects
and 102 normal participants were included. Results: There was a significant effect of the clinical condition on CS
[F(1,209)=5.409, p=0.02]. The effect of age on CS was also significant [F(3,209)=20.419, p<0.001]. The interaction
between age and clinical condition was not statistically significant [F(3,209)=0.815, p=0.49]. CS of POAG suspects
was significantly lower than that of the normal group for the younger age groups (40 to 59 years old) but not for the
older age groups (50 to 80 years old). There was no significant effect of clinical condition on CCT [F(3,209)=0.754,
p=0.39]. However, there was a significant effect of age on CCT [F(3,209)=3.789, p=0.01]. Conclusion: Contrast
sensitivity measurement is potentially useful to be integrated with routine investigations for POAG suspect patients,
especially those who are younger than 60 years old. Measurements of central corneal thickness alone may not be
able to differentiate between POAG suspects and visually normal individuals.