Objective To observe the impacts on the patients with cardiovascular responses when applying propofol combined with different dose of remifentanil in tracheal intubation without the use of muscle relaxants for anesthesia induction. Methods Sixty patients undergoing selective general anesthesia operation of ASA Ⅰ -Ⅱ non-heart and brain surgery were divided into three groups by random digits table, and 20 cases for each group. Target-controlled infusion of remifentanil with respective plasma concentration of 2 ng/ml (group Ⅰ ), 3 ng/ml (group Ⅱ ) and 4 ng/ml (group Ⅲ). Target-controlled infusion of propofol after infusion of remifentanil for 5 min (3 μg/ml of plasma target concentration). The mean arterial pressure (MAP),heart rate (HR), intubation conditions and success rate of patients in different groups before induction(T1), at the beginning moment of propofol(T2),at the immediate moment before tracheal intubation (T3) and at the time of 1 min after tracheal intubation (T4). Results The grade of tracheal intubation was (10.5 ±2.9), (7.6 ±2.3), (5.8 ± 1.2) scores and the success rate of the first intubation was 50%( 10/20), 80%(16/20), 100%(20/20) in group Ⅰ ,Ⅱ and Ⅲ , there were significant differences among three groups (P＜ 0.05),group Ⅲ was superior to group Ⅰ and Ⅱ (P＜0.05). Comparing T2 and Tj,HR in group Ⅱ and Ⅲ slowed down significantly ( P ＜ 0.05), and in group Ⅲ slowed down more significantly (P＜0.05). Comparing T4 and T3,HR in group Ⅰ and Ⅱ quickened significantly, and group Ⅰ was higher than group Ⅱ and Ⅲ (P＜ 0.05). Comparing T3 and T2,MAP decreased significantly among three groups,comparing T4 and T3, MAP increased significantly in group Ⅰ which was higher than that in group Ⅱ and Ⅲ (P ＜ 0.05). Conclusions Without the use of muscle relaxants, propofol combined with remifentanil for 3-4 ng/ml can better restrain the tracheal intubation stress responses and won't cause significant cycle inhibition. They benefit to maintain the smooth intubation process of anesthesia induction.

Data mining technology can provide higher-level data analysis functions to hospital managers and offer strong technical support to the formulation of competitive strategies by the hospital. The authors identify four data mining tasks, viz. data sampling, classification, clustering and association rules and give an account of the methods frequently used in data mining. They point out that data mining technology has wide applicability in medical quality control, outpatient and emergency care control, ward control, hospital resources allocation and hospital economic management. They argue that with the wide and further application of information technology, hospital management will move to a significantly higher level.

0.999 9).The minimum quantitative concentrations were 0.027 ?g?mL-1,0.033 ?g?mL-1,0.095 ?g?mL-1,respectively.The 3 kinds of organic solvents were not found in each batch except 0.10% and 0.15% ethyl acetate was found in 2 batches of samples.CONCLUSIONS:The established method is accurate,sensitive and accurate for the determination of 3 kinds of residual organic solvents in beclometasone dipropionate simultaneously.

OBJECTIVE:To observe clinical efficacy of specific 5-HT receptor antagonist granisetron combined with intravenous local anesthetic lidocaine pretreatment in minimizing propofol injection pain. METHODS:400 selective patients with laparoscopic cholecystectomy randomized into control group(group A),lidocaine group(group B),granisetron group(group C)and lidocaine combined with granisetron group(group D),n=100. Group A were treated with 3 mL normal saline and group B 20 mg lidocaine,group C 2 mg granisetron,group D 2 mg granisetron and 20 mg lidocaine. After 1 min the tourniquet released and a quarter of expected amount of propofol was given. Pain score of injection site was recorded. RESULTS:As group B、C and D,case number of injection nonpain in group A was higher than that of injection pain. There were statistical significance in the difference of case number and degree of injection pain among those groups(P

Objective To study the effect of Tongxiening Keli in combination with Birid Triple Viable (BIFICO) in treatment of post-infectious irritable bowel syndrome(PI-IBS) .Methods 112 cases of diarrhea-predominant PI-IBS were divided into combina-tion treatment group(n=60) and control group(n=52) .Combination treatment group received both Tongxiening Keli and BIFICO treatment ,while the control group received BIFICO treatment only .After 6-week treatment ,the therapeutic effect were compared between the two groups .Results The intestinal symptoms grading of combination treatment group was significantly lower than that of control group(P<0 .05);The total effective rate of combination treatment group was 91 .7% ,the total effective rate of con-trol group was 65 .4% ,curative effect in combination treatment group was superior to the control group (P<0 .01) .Conclusion Tongxiening Keli combined with BIFICO is evident effective in treatment of diarrhea-predominant PI-IBS .

Solid tumor growth and metastasis depends on angiogenesis.Anti-angiogenesis cancer therapy research has become one of the hot topics.Studies have shown that many kinds of Chinese medicine have an effectiveness of anti-tumor angiogenesis. It is one of the most important mechanisms to anti-tumor Chinese medicine.Chinese medicine on the anti-tumor angiogenesis research in recent years will be reviewed.

Objective To study the radiation protection and its molecular mechanism of the polysaccharide from Monostroma nitidum. Methods The mice were randomly divided into the normal group, the model group and 3 treatment groups. Polysaccharide from Monostroma nitidum was applied to the treatment group for 15 d before irradiation with 6.0 Gy rays. 30-day survival rate was observed. The counts of peripheral white blood cell, thrombocytes and erythrocytes were measured. The activities of the antioxidant enzymes SOD and GSH-Px were assayed , and the damage to the cell membrane was studied by measuring the lipid peroxides MDA levels. The spleen index and transformation response of splenic lymphocyte were determined. Results 30 day survival rate significantly increased in the polysaccharide groups. The animal experiment showed the counts of peripheral white blood cell, thrombocytes and erythrocytns were significantly and more rapidly recovered in the polysaccharide group after irradiation. The polysaccharides markedly increased the activities of GSH-Px and SOD and decreased the levels of MDA in the blood. In the irradiated mice, the polysacchaxide significantly increased the spleen index and transformation response of splenic lymphocyte when compared with irradiation mice.Conclusion The present observations suggest that the polysaccharide from Monostroma nitidum had a marked redioprotective effect on irradiated mice and that the biological response might be caused by the hematopoiesis recovery, antioxidant effect and immune activation.

Background and purpose:Nausea and vomiting were the most common side effects of chemotherapy and they are difficult to control especially in terms of delayed nausea and vomiting induced by CDDP. Acupuncture treatment is popularly the traditional medical method used in China,being economic and easy to carry out.This research is to study the role of acupuncture treatment in the prevention of NP regimen induced delayed nausea and vomiting. Methods:26 patients with NSCLC were enrolled into a randomized double blind crossover trial. The patients received either hydrochloride ondostrone+Dexm+acupuncture treatment(the first cycle of chemotherapy) →hydrochloride ondostrone+Dexm (the second cycle of chemotherapy)(defined as AB group) or hydrochloride ondostrone+Dexm (the first cycle of chemotherapy)→hydrochloride ondostrone+Dexm+acupuncture treatment (the second cycle of chemotherapy)( defined as BA group).Results:Twenty six patients were evaluated. The complete controls of nausea for the AB group with acupuncture treatment were 96.15%, 96.15%, 76.92%, 84.62%, 92.31% and 100.00% for day 1-6, respectively, for the BA group without acupuncture treatment were 100.00%, 76.92%, 57.69%, 34.62%, 65.38% and 76.92%, respectively. There were statistically difference in terms of the control of nausea for day 3-5(P

This is to retrospectively review and summarize the ultrasonic images of 214 patients who were diagnosed as clonorchiasis and received treatment. The major changes in ultrasonography were found in gallbladder and hepatic bile duct. Flocculent echos in the gallbladder were the characteristic feature,which disappeared after chemotherapy. The wall of hepatic bile duct became thicker and shaggy in most patients. These changes improved quite slowly after treatment. Ultra-sonography is of value in the diagnosis of clonorchiasis sinensis

Objective To investigate the efficacy of mifepristone in the treatment of early ectopic pregnancy and its effect on the fertility of patients. Methods 90 patients with early ectopic pregnancy admitted in our hospital from January 2011 to December 2012 were randomly divided into two groups. The control group was treated with methotrexate. The combination group was treated with mifepristone. Patient treatment effectiveness and fertility. Results There were no significant differences in β-HCG (human chorionic gonadotropin) and mass in the two groups before treatment. After treatment, the patients were significantly improved, the study group was significantly better than the control group (P<0.05). The rate of intrauterine pregnancy was significantly higher in the study group than that in the control group (P<0.05). The rate of ectopic pregnancy and secondary infertility were significantly lower than those of the control group (P<0.05 ). The incidence of adverse reactions in the study group was lower than that in the control group (P<0.05). Conclusion The efficacy of mifepristone in the treatment of early ectopic pregnancy is ideal for the retention of patient fertility and should be promoted.