1.Compound flap transplantation in the treatment of 20 patients with scar of functional position after burns
Jiande YANG ; Yuanqiang WEI ; Hailong MO ; Santong LUO
Chinese Journal of Tissue Engineering Research 2007;0(08):-
AIM: To observe the restorative effect of compound flap transplantation on the scar of functional position after burns. METHODS: Twenty inpatients with scar of functional position after burns treated by compound flap transplantation were selected from the Department of Burns and Plastic Surgery, First Hospital Affiliated to Liuzhou Medical College between May 2002 and December 2005, and all patients knew and agreed with the items. All patients were removed of the scar of functional position under whole-anesthetization to transplant the acellular allogenic dermis (It was manufactured by Beijing Dieyalaifu Biotechnological Co., Ltd of Guangxi Beisheng Pharmaceutical Group, and it was characteristics of soft, flexible with better tenacity. Besides, it was milk white in net with two kinds of surfaces: smooth surfaces and rough surfaces). Acellular allogenic dermis of rough surface closely adhered to the wound with smooth surface up toward, and the wound was sutured. Autologous skin grafts (obtained from scalp, trunk or extremities) were transplanted into acellular allogenic dermis, and the flap gaps shall be kept as small as possible, so as to reduce the exposure of acellular allogenic dermis. Wounds were dressed at 2 weeks postoperation, and the follow-up was conducted regularly. The survival rate, contraction rate, the smooth and glossy degree, skin elasticity, joint function, and healing of donors were observed from 2 weeks to one year after the surgery. RESULTS: Twenty patients were followed after compound flap transplantation with the time ranged from one month to one year, including 4 patients within 1-3 months, 3 patients within 3-6 months, and 13 patients within 6 months to one year. Thirty functional positions out of 31 healed in the first period. While the flap in another position was influenced by exposed acellular allogenic dermis due to over large gaps among autoallergic flaps. The survival rate of transplanted flap was 93.00%, and the flaps transplanted were smooth in appearance with proper elasticity and less contraction, and the joint range of motion was better. The skin of donor site recovered better. CONCLUSION: Compound flaps can significantly ameliorate the functional disturbance and deformities caused by scar of functional position after burns with high survival rate.
2.Analysis of liver function and myocardial enzyme level of 395 cases with infantile rotavirus enteritis
Qian WU ; Qiwu WU ; Hailong ZHANG ; Wenwen YANG ; Zhuangbin MO ; Xiaofeng BIAN ; Chaochang HONG
Chinese Journal of Primary Medicine and Pharmacy 2018;25(2):193-196
Objective To detect the damage incidence rate of liver and myocardium in infantile rotavirus (RV) enteritis.And to provide the basis for prevention and cure of liver and myocardium damage in infantile RV enteritis.Methods The liver function and myocardial enzyme detection results of 395 patients with infantile RV enteritis were collected .These results were compared with those of 40 healthy kids from health examinations . Results The levels of alanine aminotransferase ( ALT ) , aspartate amino transferase ( AST ) , serum creatine kinase (CK) and serum creatine kinase isozyme(CK-MB) from infantile patients were (34.49 ±29.13)U/L,(52.44 ± 24.10)U/L,(141.75 ±132.22)U/L and (48.69 ±32.53)U/L,respectively,which were higher than those of the healthy control [(16.00 ±3.24)U/L,(29.90 ±3.76)U/L,(101.82 ±64.56)U/L and (22.32 ±8.98)U/L,t=4.008,5.901,3.982,5.64,all P<0.05].The abnormal occurrence rates of ALT ,AST,CK and CK-MB in infantile patients were 19.49%,73.16%,12.15%,73.16%,respectively,which were higher than those in healthy controls (2.50%,20.00%,0.00%,0.00%),the differences were statistically significant (χ2 =7.128,47.397,5.464, 300.239,all P<0.05).The incidence rates of liver and myocardium damage were 19.49%and 73.16%,respectively. Conclusion There are higher incidence rates of liver and myocardium damage in infantile RV enteritis .So for the infantile RV enteritis patients ,it is necessary to detect the liver function and myocardial enzyme level .The treatment for infantile RV enteritis should be included liver and myocardial protection except antivirus and correcting dehydration .