Objective:To observe the clinical effects of tuina manipulations plus the functional training on scapulohumeral periarthritis (SP), and provide the better therapeutic plan for SP patients. Methods: A total of76 cases with SP in conformity with the inclusion criteria were randomly divided into a tuina group and an acupuncture group, 38 patients in each group. All the patients were instructed to do functional training under the guidance of the professional medical practitioners. The patients in the tuina group were treated additionally with tuina manipulations, while the patients in the acupuncture group were added with acupuncture treatment. The two groups were treated once every day. After ten sessions, the changes in the scores of visual analog scale (VAS) and Melle were observed, and the clinical effect was compared. Results:After the treatment, VAS and Melle scores were all lower in the tuina group than those in the acupuncture group, with statistical significances between the two groups (P<0.05). The remarkable effective rate was 5.3% in the acupuncture group and 21.1% in the tuina group. The remarkable effective rate was higher in the tuina group than that in the acupuncture group, with a statistical significance (P<0.05). Conclusion:Tuina manipulations plus functional training for SP can effectively alleviate pain and restore the functions of the shoulder joint, with a better effect than acupuncture plus functional training.

BACKGROUND:The cruciate ligament of the knee joint has a poor capacity of self-healing after injury, and the main treatment is grafting to reconstruct cruciate ligament.
OBJECTIVE:To summarize the structure, function, and mechanical characteristics of anterior cruciate ligament of the knee joint, the present research of artificial ligament reconstruction fol owing damage, and to provide evidences for clinical application of artificial ligament.
METHODS:An online computer-based retrieval was performed with the key words of“artificial y synthetic materials, knee joint cruciate ligament, exercise, ligament repair, ligament reconstruction”. Articles related to knee ligament treatment approach, materials science characteristics, biocompatibility and application were included. A total of 25 articles addressing the properties of biological materials applied in knee cruciate ligament reconstruction were screened.
RESULTS AND CONCLUSION:As an effective treatment for anterior cruciate ligament injuries, technique of anterior cruciate ligament reconstruction has been developed in recent years. Implants for repairing anterior cruciate ligament injuries include autologous ligaments, ligament al ograft, artificial ligaments, and tissue engineered ligament. Artificial materials and tissue engineered ligaments are the hotspots in recent years. Biological artificial ligament is effective to treat the knee ligament injury. celland molecular biology techniques as wel as the use of gene therapy wil become a new direction in the treatment of knee ligament injury and rehabilitation.

Objective:To explore the main influencing factors for cardiopulmonary resuscitation (CPR ) in patients with perioperative cardiac arrest .Methods:A total of 168 patients ,who received surgery and suffered from cardiac arrest during perioperative period in our hospital from Jun 2012 to Jun 2014 ,were selected .According to recovery outcome of spontaneous circulation ,they were divided into success group (n=67) and failure group (n=101) .Case information were retrospectively analyzed in two groups ,including American Society of Anesthesiologists (ASA) class at hospitalization ,surgical sites ,monitor before cardiac arrest ,location when cardiac arrest occurred , dose of amiodarone ,volumes of bleeding and blood transfusion ,time of cardiac arrest during surgery ,CPR duration and timing etc .,and they were statistically analyzed between two groups .Results:There were significant difference in ASA class ,location when cardiac arrest occurred ,baseline ECG rhythm ,shock before cardiac arrest ,adrenaline dose ,CPR duration and timing between two groups ,P<0.05 or <0.01. Multifactor Logistic regression analysis in‐dicated that being outside operating room when cardiac arrest occurred (OR=9.72 ,95% CI=3.16~67.33) ,non-shockable rhythm (OR=8.33 ,95% CI=2.77~22.87) ,shock before cardiac arrest (OR=5.17 ,95% CI=3.23~16.13) ,adrenaline dose (OR=6.84 ,95% CI=2.61~44.75) ,CPR duration (OR=6.14 ,95% CI=1.77~17.21) and CPR timing >1min (OR=7.51 ,95% CI=2.57~41.93) were independent risk factors for prognosis of periop‐erative CPR , P< 0.05 or < 0.01. Conclusion:Being outside operating room when cardiac arrest occurs , non -shockable rhythm ,shock before cardiac arrest ,adrenaline dose ,CPR duration and CPR timing > 1min are inde‐pendent risk factors for prognosis of perioperative CPR . Cardioc arrest calls for instant CPR .

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OBJECTIVE:How to explain and predict individual difference of artificial cochlea so as to evaluate rehabilitative effect of implant has been paid much attention by audiological scholars,clinical physicians,patients,and their relatives. This study was designed to analyze and evaluate rehabilitative status of patients accepting artificial cochlea implantation to investigate the relative influential factors of auditory rehabilitation. METHODS:A total of 28 patients were selected from Department of Otolaryngology Head and Neck,Affiliated Hospital of Qingdao Medical College from June 2002 to April 2008. They were accessed by age,time of rehabilitation training,usage of hearing aids,audiology and aural image before surgery,and NRT monitoring in cochlear implantation so as to observe auditory improvement. The clinical results were analyzed to detect the effect of various factors on auditory rehabilitation. RESULTS:Age,preoperative preparations and good audiology and aural image are important premises for a successful rehabilitation. Longer the time of using hearing aids and language rehabilitation are,and better results will get. NRT response during operation is also an important factor for good auditory rehabilitation. CONCLUSION:The influential factors of auditory rehabilitation after cochlear implant included the age,audition remains,usage of hearing aids,NRT response during operation,and the time after the cochlear implant operation.

Objective To investigate the effect of rehabilitation nursing system of manipulative reduction and tradi-tional Chinese medicine fumigation treatment to alleviate the clinical stage of lumbar intervertebral disc protrusion promoting effect.Methods 200 cases of remission in patients with lumbar disc herniation were divided into intervention group and con-trol group with 100 cases in each group, the control group of the implementation of general nursing, intervention group re-ceived rehabilitation nursing system based on general nursing.Results 20 days later, compare the lumbar function score, the intervention group was significantly better than the control group, and the difference was statistically significant (p<0.01). The intervention group: the total efficiency of 98%.Control group: the total efficiency of 85%.The total efficiency of two groups were significant difference ( p <0.05 ) .Conclusion rehabilitation nursing treatment to alleviate the superposition effect of lumbar disc herniation, has an important significance to improve the clinical efficacy and quality of life.

Biomarkers, Tumor ; Humans ; Lung Neoplasms ; Mesothelioma

BACKGROUND: Neuron-specific enolase, γtype isoenzyme that is specially present in the cytoplasm of neurons and neuroendocrine cells, is considered as a sensitive predictor for neuronal damage.OBJECTIVE: To observe the changes of serum neuron-specific enolase in patients with transient brain ischemic attack, so as to explore its relationship with the degree of neuronal damage.DESIGN: Case-control observation.SETTING: Department of Neurology, Jinan No. 4 People's Hospital.PARTICIPANTS: A total of 29 patients who were hospitalized in the Department of Neurology, Jinan No. 4 People's Hospital, due to transient brain ischemic attack (all called for emergent medical treatment within the onset of 6 hours) between March 2002 and May 2004 were enrolled in this study. There were 18 males and 11 females with the average age of(60.36t11.67) years. According to the duration of neural functional deficits, all subjects were divided into two groups, namely, transient-symptom group (≤ 6 hours) of 19 cases and lasting-symptom group (＞ 6 hours)of 10 cases. At the same time, 25 healthy controls, 15 males and 10 females with the average age of (62.34±9.65) years, rere selected from those who came for routine health examination.METHODS: Fasting elbow venous blood of 1 mL was collected only once from the subjects in control group; the same amount of blood was collected from the patients in transient ischemic attack group immediately after hospitalization, and at days 2, 3, 4 and 5. Roche Elecsys 2010 automatic analyzer was used to detect serum neuron-specific enolase. Neuronal damage was assessed with neurological deficit scale (defined as practical recovery if scores were reduced by 90%-100%; remarkable improvement if scores were reduced by 46%-89%; improvement if scores were reduced by 18%-45%; ineffective if scores were reduced by less than 17% or even the disease aggravated).MAIN OUTCOME MEASURES: The daily changes of serum neuronspecific enolase.RESULTS: All the54 subjects remained in the final result analysis. [1]Comparison of neuron-specific enolase density: It was significantly higher in transient brain ischemic attack group than in control group [(23.53±12.35) vs(14.29±6.83) μg/L, t=2.678, P ＜ 0.01]. [2] Curve of neuron-specific enolase changes during the acute stage: It began to increase at the early stage,reached the peak level on the next day, and gradually declined to the normal level in 4-5 days. [3] The level of serum neuron-specific enolase in the two groups with various durations of neurological deficit symptoms: It was obviously higher in transient-symptom group than in control group [(19.24±8.95)vs (14.29±6.83) μg/L, t=1.893, P ＜ 0.05], and higher in lasting-symptom group than in control group [(28.87±13.15) vs (14.29±6.83) μg/L, t=4.367,P ＜ 0.001]. [4] The level of neuron-specific enolase was positively correlated with the duration of neuronal damage (r=0.815, P＜0.01).CONCLUSION: Serum neuron-specific enolase increases within a short term after transient brain ischemic attack and reaches the peak level at around 24-36 hours, suggesting that the detection of serum neuron-specific enolase has a guiding value in assessing the severity of transient brain ischemic attack.

Objective:To investigate the compliance with early Warfarin anticoagulation therapy after cardiac mechanical valve replacement(MHVR)and its related factors in elderly patients.Methods:The convenience sampling method was used to prospectively recruit 210 patients undergone MHVR at the Ningbo Medical Center of Lihuili Hospital from January 2017 to October 2019.Six months after discharge, face-to-face interviews or telephone follow-ups were conducted to assess general information, warfarin anticoagulation knowledge, anticoagulant treatment compliance and social support.Results:The overall compliance of early Warfarin anticoagulation therapy was excellent, with 99.5% of patients compliant with medication and 99.0% compliant with INR monitoring, both higher than the rate of compliance with advised lifestyle adjustment(92.1%). Anticoagulation knowledge and age were the main influencing factors for compliance in elderly patients after MHVR.Conclusions:The compliance with early Warfarin anticoagulation therapy after MHVR is good in elderly patients in the Ningbo area.The correlation analysis suggests that medical professionals need to promote education on anticoagulation knowledge and pay more attention to anticoagulation compliance in elderly people.

Objective To investigate the value of TI-RADS for sonographic diagnosis of papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) and to evaluate the sonographic findings of FTC compared to PTC.Methods The clinical and sonographic data of 363 cases of pathology confirmed thyroid nodules were retrospectively analyzed.The thyroid nodules were classified by TI-RADS grading criteria,the accuracy of TI-RADS and sonographic findings between FTC and PTC was analyzed.Results In 363 thyroid nodules,114 cases were confirmed as benign lesions;249 cases were confirmed as carcinomas,including 50 FTC cases and 199 PTC cases.The sensitivity,specificity,PPV,NPV,and accuracy of PTC were 97.0％ (193/199),85.1％ (97/114),91.9％ (193/210),85.8％ (97/113),95.7％ (290/303) respectively.The sensitivity,specificity,PPV,NPV,and accuracy of FTC were 97.0％(193/199),85.1％ (97/114),91.9％ (193/210),85.8％ (97/113),95.7％ (290/303) respectively.There were significant differences of nodule size,shape,margin,echogenecity,calcification,halo and flow between FTC group and PTC group (P ＜ 0.05).Conclusion TI-RADS has higher value in the sonographic diagnosis of PTC than that of FTC.FTC are greatly different from PTC in many sonographic findings making it less valuable for the diagnosis of FTC.