Objective To understand the Providencia rustigianii status of the hospital infection and drug re -sistance.Methods From June 2011 to August 2013,39 Providencia rustigianii cases of infection were retrospectively analyzed.Results 39 cases of Providencia rustigianii drug sensitive experiment showed 39 strains Providencia rusti-gianii of imine pei south,amikacin resistance to a minimum.The sensitive rate was 87.2%,64.1% respectively. Conclusion For Providencia rustigianii infections ,antimicrobial imide is the preferred choice ,also can try amikacin .

ObjectiveTo compare the therapeutic effect, adverse effects and safety of leflunomide (LEF)and cyclophosphamide(CTX) on lupus nephritis(LN). Methods43 patients with reactive LN were randomly divided into two groups. Based on hormone application,22 cases in LEF group were given LEF orally and 21 cases in CTX group were given CTX intravenous drip discontinuously. They were followed up for six months. The related indexes and possible concomitant adverse effects were detected. ResultsThe total effective rate in LEF group was 81.8％ and that in CTX group was 85.7％. The tolerance in LEF group was better and 3 cases had adverse effects. 13 cases in CTX group had adverse effects. ConclusionLEF had the same efficacy as CTX in the LN therapy, but the tolerance is better and the side effects are minor than CTX.