329 subjects (234 males, 94 females) with cerebro cranial trauma were treated at Dien Bien Phu Hospital in Lai Chau province from January 1st 1994 to December 31st 1998. Results: 8/329 cases were refered to other hospital because of various other causes. 283 cases (88.16%) among them underwent internal management. 38 cases (11.84%) surgeried. Mean duration of treatment was 7.4 days. Mean post operative care 12.2 days. 293/312 cases were recovered generally (91%). Post operative recoverd cases accounted for 25/38 cases (65%) among them 22 cases were completely recovered (88%). No negligible trauma was detected at autopsy. In the conditions of basic level health facilities, X ray craniography was necessary, needing an early management.
Craniocerebral Trauma ; Therapeutics ; Diagnosis

15 experimental dogs with stainless steel plates and screws fixed in the femur were enrolled into a controlled study to assess histological outcome manifested surrounding the sites of intervention. Plates and screw were firmly attached to the bone. No abnormal reaction was observed macroscopically and microscopically. No inflammatory cells were found after a 45, 90, 135, and 180 days follow-up. The structure and the thickness of the connective membrane in contact with the fixed material had a tendency to become more and more stable. From the day 90, no differences were noted between the group of experimental animals and the control subjects using Chinese SMIC material.
Femoral Fractures ; Bone Screws

Adult ; Aged ; Aged, 80 and over ; Combined Modality Therapy ; Female ; Humans ; Male ; Manipulation, Orthopedic ; methods ; Middle Aged ; Radius Fractures ; surgery ; Splints ; Traction ; methods

Animals ; Dose-Response Relationship, Drug ; Female ; Humans ; Metals, Heavy ; analysis ; pharmacology ; Placenta ; chemistry ; drug effects ; physiology ; Pregnancy ; Rats

Objective To explore the value of computed tomographic DacryocystographyCT-DCGand computed tomographic three-dimensional3Dreconstruction with lacrimal passages in asymptomatic lacrimal flow patients with nasal structural abnomalities. Method: In 2006-2010, 18 nasal structural abnomalities cases with asymptomatic lacrimal flow and nasal obstruction were enrolled, the lacrimal flow caused by ocular region was obviated. Of all the 18 hypertrophic inferior turbinate cases, there were 12 cases accompanied with nasal septum deviation. The radiofrequency ablation of inferior turbinate and nasal septum deviation surgery under nasaI endoscope were takenThe CT-DCG and 3D reconstruction examines were observed preoperative and postoperative. All the patients were followed-up for 12 months. Result: 18 nasal structural abnomalities were corrected. The nasal obstruction were recoveried and improved in 1477.8%and 422.2% cases respectively. The symptom of epiphora had disappeared and improved in 1372.2% and 5 cases27.8%. Partial obstruction of the internal ostium was found preoperative and resolved postoperative with CT-DCG and 3D reconstruction. Conclusion: CT-DCG and 3D reconstruction can evaluate the asymptomatic alterationsof the normal lacrimal outflow in cases with nasal structural abnomalities, suggesting that they have great value in clinical applications.

OBJECTIVE: To establish a auantitative analysis of multi-components by single marker(QAMS) method for determining the content of anthraquinones in Dabaidu capsules(traditional Chinese medicines). METHODS: The relative correction factors (RCFs) of emodin to rhein, chrysophanol, and physcion were determined on a C18 column (4.6 mm × 250 mm, 5μm) with methanol-0.1% phosphoric acid (85:15) as mobile phase. The flow rate was 1.0 mL · min-1. The column temperature was set at 25°C. The detection wavelength was set at 254 nm. The relative retention time (RRT) was used to define the target peak. RESULTS: The calibration curves for rhein, emodin, chrysophanol, and physcion showed good linearity in the ranges of 5.724 × 10-2-0.5724 μg, 4.584 × 10-2 -0.4584 μg, 6.368 × 10-2-0.6368 μg and 6.548 × 10-2 - 0.6548 μg, r(0.9997-0.9999), respectively. The recoveries were (97.8 ± 1.4)%, (100.7 ± 1.0)%, (98.6 ± 0.6)% and (97.0 ± 1.4)%, respectively. The RCFs were 1.19, 1.40 and 1.06. CONCLUSION: The method is simple, rapid, accurate and reliable. It can be applied to control the quality of anthraquinones in Dabaidu capsules.

Objective:To explore the result of application of the clinical nursing pathway on percutaneous coronary interventional patient.Methods:One hundred patients were divided into two groups randomly,each group has 50 cases.We used the clinical nursing pathway based on holistic nursing case in experimental group,and the control group used the holistic nursing care.Results:After use the method of the clinical nursing pathway in the hospital,the medical cost and the rates of the nursing errors were less than that in the comparing group while the patients were more satisfied.Conclusion:As a scientific mode,the clinical nursing pathway could improve the working efficiency,guarantee the nursing quality.

Objective To explore the possible association between human leukocyte antigen(HLA) allele polymorphism and susceptibility to chlidren's acute lymphocytic leukemia(ALL).Method HLA alleles polymorphism in 38 cases with ALL and 35 healthy controls were determined by polymerase chain reaction(PCR) with sequence specific olignuleotide probe(PCR/SSO).Results The allele frequency of HLA-A01 significantly increased than control group(?2=4.947 P=0.026,RR=10.20),the frequence of A02 significantly decreased(?2=4.187 P=0.041,RR=3.13),the frequcnce of A33 significunt decreased than control group(?2=4.403 P=0.036,RR=0.21).Conclusion These results show that susceptibility to chlidren's ALL is positively related to HLA-A01,A33,especially A01 allele,while HLA-A33 to its genetic resistance.

Adult ; Humans ; Male ; Mediastinitis ; complications ; Neck ; Peritonsillar Abscess ; complications

· AIM: To investigate the efficacy and safety of intravitreal injection of plasmin, hyaluronidase, or the combination of the two in inducing posterior vitreous detachment (PVD).· METHODS: 15 mini-type pigs were assigned to three groups (Group A, B and C), 5 in each group. One eye of each pig was intravitreally injected with the studying agent,and the fellow eye was used as control. Group A received a vitreous injection of hyaluronidase 50U (0.1mL); group B received plasmin 0.5U (0.1mL); group C received plasmin 0.5U (0.05mL) combined with hyaluronidase 50U (0.05mL). The fellow eyes in each group were injected with 0.1mL balanced salt solution (BSS). All the pigs were examined with slit-lamp biomicroscope, direct and indirect ophthalmoscope, B-scan and electroretinograph (ERG). After 7 days, the animals were killed and the eyes were enucleated and examined with light microscope, transmission electron microscope and scanning electron microscope.· RESULTS: B-scan examination showed that one eye of Group A and two eyes of Group B had partial PVD at 1st day after injection and one eye of Group C at 1 hour after injection. On the 7th day, B-scan, light microscopy and scanning electron microscopy demonstrated that all the eyes of Group A and Group B had partial PVD, while none of the control eyes had PVD. Rank sum test for scanning electron microscopy results of all the groups showed P ＜0.005.Furthermore, the comparisons between every two groups were made. The results of analyses were as follows: P＞0.05 between the drug injected eyes of Group A and Group B, P＜0.05 between Group B and Group C, Group A and Group C.The b-wave and a-wave amplitudes of ERG showed no significant difference either between preinjection and postinjection in all groups or between the drug injected eyes and the control eyes in each group. Light microscopy and transmission electron microscopy revealed no damage to the retinal structure.· CONCLUSION: Intravitreal injection of hyaluronidase 50U or plasmin 0.5U or their combination can produce PVD effectively and quickly without retinal functional or structural toxicity. The combination of the two proteases was proved to be synergetic.