1.Risk Factors Associated with Contact Lens Related Microbial Keratitis
Lili Asma Ismail ; Lekhraj Rampal ; Hejar Abdul Rahman ; Nazri Omar ; Habshah Midi ; Azrin Esmady Ariffin
Malaysian Journal of Medicine and Health Sciences 2016;12(1):1-8
Introduction: Microbial keratitis is one of the most challenging complications of contact lens (CL)
wear. Proper CL practice plays an important role to reduce the risk for contact lens related microbial
keratitis (CLRMK). Methods: This multi-centre case-control study was conducted from January 2008
until June 2009 to determine the risk factors associated with CLRMK. Cases were defined as respondents
who were treated for CLRMK, whilst controls were respondents who were contact lens wearers without
microbial keratitis. Ninety four cases were compared to 94 controls to determine the risk factors for
CLRMK. Results: The predictors for CLRMK were: Not washing hands with soap before handling CL
(aOR 2.979, CI 1.020, 8.701 p=0.046), not performing rubbing technique whilst cleaning the CL (aOR
3.006, CI 1.198, 7.538 p=0.019) and, not cleaning the lens case with multipurpose solution daily (aOR
3.242 CI 1.463, 7.186 p=0.004). Sleeping overnight with the CL in the eye (aOR 2.864, CI 0.978, 8.386
p=0.049) and overall non-compliance with lens care procedures (aOR 2.590, CI 1.003, 6.689 p=0.049)
contributed significantly to CLRMK. Conclusion: Health education and promotion in contact lens care
are important and should be conducted by eye care practitioners to reduce the occurrence of CLRMK.
Contact Lenses
2.Visual Status following Contact Lens Related Microbial Keratitis
Lili Asma Ismail ; Lekhraj Rampal ; Nazri Omar ; Hejar Abdul Rahman ; Habshah Midi ; Azrin Esmady Ariffin
Malaysian Journal of Medicine and Health Sciences 2016;12(2):24-29
Introduction: A hospital based case control study was
conducted in government hospitals on contact lens patients
diagnosed with microbial keratitis. Methods: The objective of
this study is to determine the visual outcomes of contact lens
related microbial keratitis. The visual outcomes which
comprised of visual acuity, keratometry readings, corneal
topography findings and contrast sensitivity examinations was
determined after three months from the first presentation at the
hospitals. Results: The mean LogMAR visual acuity during
presentation was 0.96 ± 0.73 or a Snellen equivalent 6/60 (n=76)
and mean LogMAR visual acuity after three months was 0.10 ±
0.48 or a Snellen equivalent 6/7.5 (n=76) with a significant
difference (t=11.22, df=78, p=0.001). Best fit curve for the cases
had a regression coefficient, r=0.350 ± 0.063 (95% CI = 0.224,
0.447, df=78, p=0.001. The visual acuity in cases and controls
was 0.10 ± 0.48 and -0.10 ± 0.14 respectively (t= -3.61, df=154
p=0.001) after three months which showed improvement. There
was a reduction in the corneal uniformity index and corneal
asphericity in the cases. The Corneal Uniformity Index (CU
index) in cases was 63.03 ± 26.38 (n=76) and in controls, 80.13
± 11.30 (n=77), (t= -5.22, df=151, p=0.001). There was also a
reduction in the contrast sensitivity function at all spatial
frequencies in the cases which was significantly different.
Conclusion: Microbial keratitis reduced the vision, corneal
uniformity index, asphericity and contrast sensitivity after three
months in eyes of patients diagnosed with the condition.
Keratitis
;
Eye