No abstract available.
Humans*

No abstract available.
Humans

No Abstract available.
Humans

Ginseng Radix(GR) had been used widely from oriental medicine and the effects of it have been investigated by many researchers. The purpose of present study was to investigate the effects of GR on the cell cycle progression and its molecular mechanism in human fetal osteoblast. The results were as follows. Increased cell proliferation was observed in cells exposed to 100 ng/ml, 10 ng/ml of GR-1 at 12 hours and 24 hours, 1 microgram/ml of GR-1 at 48 hours, and 100 microgram/ml, 10 microgram/ml of GR-2 at 12 hours, all treatment groups of GR-2 at 24 hours(p<0.05). S phase and G1 phase was increased in the group of treated with 100 ng/ml of GR-1, with 10 microgram/ml and 1 microgram/ml of GR-2, with 100 microgram/ml and 10 microgram/ml of GR-3 in the cell cycle analysis. The cell cycle regulation protein levels of Cyclin D1, Cyclin E, CDK 2, CDK 4 and CDK 6 were increased in the group of treated with 1 microgram/ml and 100 ng/ml of GR-1, with 10 microgram/ml and 1 microgram/ml of GR-2, with 100 microgram/ml and 10 microgram/ml of GR-3. On the other hand, p21 was decreased in the treatment group with 1 microgram/ml and 100 ng/ml of GR-1, with 10 microgram/ml and 1 microgram/ml of GR-2, 10 microgram/ml of GR-3, and p53 and p16 was decreased in the treatment group with 100 ng/ml of GR-1, 100 microgram/ml GR-3 and pRb was decreased in the all treatment groups except 1 microgram/ml of GR-1. These results suggested that GR increases the cell proliferation and the cell cycle progression in human fetal osteoblast, which is linked to increased cell cycle regulation protein levels of Cyclin D1, Cyclin E, CDK 2, CDK 4, CDK 6 and decreased cell cycle regulation protein levels of p21, pRb.
Humans

No abstract available.
Humans

Despite the increasing number of patients with human immunodeficiency virus (HIV) infection, surgical experience with these patients remains limited in Korea. Patient with HIV infection may require surgery for the reasons similar to those anyone else might need an operation for or because of problems related to their viral illness. Surgeons feel threatened by the risk of contamination when operating on HIV-seropositive or AIDS patients. However, the exclusion of patients from treatment is unethical on ground of contamination risk. Therefore the surgeons have to reconsider their surgical strategy and technique in order to keep chances of contamination as low as possible. We report a case in which the AIDS patient has undergone an operation for gastric bezoar. To our Knowledge, this is the first report of laparotomy in Korea in patient with AIDS.
Humans

No abstract available.
Humans

No abstract available.
Humans

No abstract available.
Humans

No abstract available.
Humans