1.Evaluation for embryonic stem cell study with the theory of Marx's ethics
Chinese Journal of Medical Education Research 2011;10(1):126-128
Stem cell has a prospective future in cells therapy.However,the harvesting of stem cells is a paradoxical issue.In fact.the essence of dispute on stem cell studies is a combat between utilitarianism and moralism.The point of view of Marx's Ethics about stem cell studies present dialectical harmony between utilitarianism and moralism.The development of an embryo is a developing process from cell mass to natural persons.but not social persons which have characteristics of sociality and consciousness.Embryo is not completely a person,so embryonic stem cell harvesting is consistent with Marx's Ethics.But the timing of harvesting stem cells and the way to deal with the embryo need further discussion.
2.The abnormity of hypothalamus-pituitary-hypothyroid axis in cerebral infarction onset and its significance
Journal of Chongqing Medical University 2008;0(S1):-
Objective:To find the effect of the abnormity of hypothalamus-pituitary-hypothyroid axis on cerebral infarction onset. Methods: Objects were divided into 3 groups: cerebral infarction group(CIG)、persons with cerebral infarction risk factor group(CIRG) and control group(CG) .The concentration of serum T3、T4、TSH、TGA and TMA on an empty stomach in each group were measured respectively by radioimmunoassay,and results were compared between each two groups by using Student t test. Results:Compared with CIRG and CG,the levels of T3、T4 in the sample of CIG were lower,and the level of TSH were higher,and there was distinctly difference(P0.01). Conclusion:This study indicated that the function of hypothalamus-pituitary-hypothyroid axis was abnormity in patients with cerebral infarction and those persons with cerebral infarctive risk factor.
4.Autologous stem cells transplantation in the treatment of critical limb ischemia
Chinese Journal of Tissue Engineering Research 2013;(49):8602-8607
BACKGROUND:Critical limb ischemia is difficult to be treated among the peripheral arterial occlusive diseases, and the application of transplanting autologous stem cells can bring a hope for the treatment of this disease.
OBJECTIVE: To review the autologous stem cells transplantation in the treatment of critical limb ischemia at present, and to study the mechanism and the existing problems.
METHODS:A computer retrieval of PubMed database, Wanfang database, and CNKI database was conducted to search the related articles with the keywords of“stem cell, transplant, critical limb ischemia”in English and Chinese. Final y, 47 articles were included in final analysis according to the inclusion criteria.
RESULTS AND CONCLUSION:Autologous stem cells transplantation for treatment of lower extremity ischemic disease is a latest and significantly effective treatment, but the mechanism is unclear and stil needs further study.
5.Influence of electroacupuncture on somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To explore influence of electroacupuncture on somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats.Methods The double-label immunofluorescence with confocal microscope was used to observe somatostatin expression of newborn neurons in the hippocampus of chronic epilepsy rats after electroacupuncture stimulation of Dazhui (GV14)' and Baihui (GV20)' in DuMai.Results Somatostatin expression of newborn neurons was found in the hippocampus.Moreover,in somatostatin expression of newborn neurons,epileptic rats with electroacupuncture had less than epileptic rats in the hippocampus.The former had an obviously significant difference compared with the latter (P
6.RELATIONSHIP BETWEEN MALIGNANT GRANULOMA AND MALIGNANT LYMPHOMA
Chinese Journal of Radiation Oncology 1995;0(02):-
This study was to compare 104 cases of malignant midline lymphoma with 69 cases of malignant granuloma in their clinical course, initial symptoms, location of lesion, extension of disease, treatment and prognosis. The two groups were similar in sex and median age. As regard to the initial symptoms such as nasal obstruction, epistaxis and nasal discharge, they were present in more than half of the patients in both groups. The primary location of lesions was in the nose (60% in both groups). As the Ann Arbor staging system is unsuitable for this disease, we compared the treatment results by area of involvement. Treatment: 74% of malignant midline lymphoma was treated by radiation and chemotherapy. 27% of malignant granuloma was treated by chemotherapy. The radiation of the two groups were 45~55Gy and 50~60Gy, respectively. The 5-year survival rates were over 90% in both groups, for those of lesion with one area involvement, 87.8% and 68% for lesions with two area involvement. 52.3% and 51.5% for three area involvement, 26.6% and 29% for four area involvement patients. Besides local uncontrol, the failure was extra-nodal invasion, such as subcutaneous nodules, pleura-peritoneal or bone marrow extensions. The authors believe that these two groups of lesions actually belong to one disease entity.
7.Clinical Observation on the Treatment of 34 Cases of Infantile Anaphylactoid Purpura with Self-made Huoxue Huayu Decoctoin
International Journal of Traditional Chinese Medicine 2009;31(4):333-
Objective To observe the effect of treating infantile anaphylactoid purpura with self-made Huoxue Huayu decoction. Methods 68 cases with infantile anaphylactoid purpura ,were randomly recruited into a control group and a treatment group, with 34 cases in each group. The control group was taken Cetirizine, Prednisone, Rutin and Vitamin C orally. The treatment group was treated with self-made Huoxue Huayu decoction on the basis of treatment in the control group. Results The total effective rate of the control group and the treatment group was 82.35% and 94.12% respectively. As compared with the effective rate in the control group, the treatment group showed significant improvement. Conclusion It was effective to treat infantile anaphylaetoid purpura with Huoxue Huayu decoction.
8.Risk factors and prognosis of cardiac arrest in children
Chinese Pediatric Emergency Medicine 2014;21(4):241-243
Cardiac arrest in children is one of the most critical clinical situations,posing a serious threat to life.With the progress of cardiopulmonary resuscitation and the advanced life support technology,children's cardiac arrest survival rate is higher than before,but many of the survivors suffer from neurological sequelae.Since the causes of out-hospital cardiac arrest and in-hospital cardiac arrest are different,their prognosis and influence factors are also different.Death risk factors for cardiac arrest in children are cancer,hepatic insufficiency,acute renal failure,sepsis,systemic inflammatory response syndrome,etc.Cardiopulmonary resuscitation,as the main emergency treatment of cardiac arrest,is also one of the main factors affecting survival of cardiac arrest child.
9.Progress of application of urodynamics in children with voiding dysfunction
Chinese Journal of Applied Clinical Pediatrics 2014;29(5):380-384
Voiding dysfunction is common in children,urodynamic study is necessary to evaluate voiding dysfunction.Recently,urodynamic studies in children with voiding dysfunction have been performed with increasing frequency as the techniques have been applied in most hospitals widely.New technologies,such as ultrasound urine flow in newborns and ambulatory urodynamics monitoring in children,have been used.Urodynamic has been used routinely in children with neurogenic bladder in China.This review summarized the application of urodynamics in children with voiding dysfunction and the relevant terminologies in pediatric urodynamics,in order to provide a reference for clinical applications and researches.
10.The effect evaluation of bronchodilation agents in the treatment of childrens with airway hyperresponsive dis-ease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(z1):1-3
Objective To objectively evaluated of the efficacy of bronchodilation agent by using pulmonary function .Methods 104 childrens with airway hyperresponsive diseases who saw doctor at the Guangdong Women and Children′s Hospital,aged 0~6 years.They were classified into three groups:salbutamol group(n=36);ipratropium bromide group(n=32) and two drugs group(n =36).Each group received salbutamol or ipratropium bromide or both.Then tidal breathing flow-volume loop and parameters were obtained before and after aerosol inhalation to evalu-ate the effects of drugs .Results There were significant improvement in each group after the inhalation of bronchodi -lators.Conclusion The two drugs of Salbutamol and ipratropium bromide can be used as the selective drugs of bron -chodilation .