To help the clinical microbiology laboratories understanding the standards of antimicrobial susceptibility testing (AST) from Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) ; discuss when to perform AST,how to confirm unusual or inconsistent results and adopt the suitable AST method,how to interpret the information of continuous monitoring development of resistance and testing of repeat isolates,how the drug-resistance mechanism influence the report and treatment.This will provide accurate and timely AST results for clinicians.

Antioxidative effects of Suaeda heteoptera Kitag. extracts were measured using thiobarbituric acid method.The results showed that extracts obtained with water,methanol and hexane gave significant resistance to the lipid peroxidation of linolenic acid and hexane extract showed the highest antioxidative activities.Mechanism of this antioxidative effect was studied using chemiluminescence.The results showed that extracts can effectively scavenge O -? 2 but have no effects on OH ?.This illustrated that the antioxidative effects were achieved by scavenging O -? 2 radical.

The role of the microvascular disease in progressive renal disease is not well understood .This review presents evidence that progressive renal disease is characterized by a progressive lose of the microvasulature. And presents the factors that induce the lose of the microvasculature. Try to find out (agents) which may represent a novel therpeatic approach for slowing the renal disease.

Purpose: To detect the prognostic factors for early primary gastrointestinal non-Hodgkin's lymphoma treated by various treatments.Materials and Methods:32 aptients with stages Ⅰ and Ⅱ primary gastrointestinal non-Hodgkin's lymphoma treated from January, 1970 to November, 1987 were retrospectively reviewed. The primary sites of cancers were: 15 in stomach, 10 in ileocecal region, 4 in large bowel and 3 in small bowel. 24 patients underwent curative resection, 7 patients underwent incomplete resection and 1,unresectable. Postoperative radiotherapy was given to all patients.Among them, 14 patients received radiotherapy plus chemotherapy.Results: The overall 5-year survival rate was 59.4%(19/32).Conclusion: The main prognostic factors are the site of primary tumor, depth of invasion, stages and modalities of managements.Sex, age, and histologic does not influence the survivals.

In recent years, there is increasing evidence that the pathogenesis of Parkinson's disease (PD) may involve the more generation of reactive oxygen species, and investigations on patients have shown that PD is under a status of oxidative stress. The defense against the toxic effects of reactive oxygen species is an essential task within the brain. An important component of the cellular detoxification of reactive oxygen species is the antioxidant glutathione. Consequently, it seems reasonable to propose that increase of brain concentrations of glutathione including glutathione analogs or precursors could be very effective in diminishing the cumulative effects of oxidative damage, and have been investigated as potential therapeutic targets in the treatment and prevention of PD or other neurodegenerative disease.

Objective To investigate the effect of psychological intervention combined with parecoxib on cognitive function in patients after liver resection of hepatocellular carcinoma. Methods From March 2015 to March 2017 in the first people's hospital of Yongkang city for diagnosis and treatment of liver cancer were 40 cases according to different nursing, drug intervention were divided into control group and observation group, the control group were treated with basic nursing + saline intervention, observation group with psychological intervention + Tenai (parecoxib sodium) intervention. The changes of cognitive function (MMSE score), inflammatory factors (TNF-α, IL-6 and S100) levels were recorded before and after intervention in the two groups, and the data obtained were analyzed and summarized. Results The psychological intervention and intervention Tenai (observation group) resection for hepatocellular carcinoma is better than the basic nursing + saline patients (control group) intervention, patients with MMSE score and TNF- α, IL-6, beta S100 levels were better than the control group, the difference was statistically significant (P<0.05). Conclusion Resection for hepatocellular carcinoma patients psychological intervention + Tenai intervention effect, it can reduce the level of inflammatory factors in patients, and has a good effect on the recovery of cognitive function after surgery.

Objective To investigate the application effect of psychological intervention combined with parecoxib in rehabilitation of patients with bile duct carcinoma after the operation. Methods According to the different intervention models from January 2015 to March 2017 in the first people's hospital of Yongkang city surgical treatment of bile duct carcinoma,40 cases of patients groups: control group with routine nursing plus saline intervention, observation group with psychological nursing + Tenai (parecoxib sodium) mode of intervention; on the psychological state of the two groups before and after intervention to improve patients the cognitive function, to improve the situation, changes in pain scores were recorded, and the related data for comparative analysis. Results The psychological nursing + Tenai (parecoxib sodium) model (observation group) intervention in the treatment of patients with bile duct cancer surgery clinical effect is better than that of routine nursing mode + normal saline (control group) the clinical effect of intervention, the psychological state of patients to improve the situation, improve cognitive function, pain score changes were better than the control group, there was statistical significant differences (P<0.05). Conclusion The surgical treatment of patients with cholangiocarcinoma patients psychological nursing + Tenai (parecoxib sodium) intervention effect significantly, can effectively improve the patients psychological status, cognitive function, and can reduce postoperative pain fully, has an excellent role in promoting the rehabilitation of patients after surgery, worthy of clinical application.