No abstract available.
Aged ; Hematologic Diseases ; Humans

At the blood transfusion and heamatology centre of Ho Chi Minh city, we performed phenotyping for 158 cases of acute leukemia diagnosed from 04/98 to 10/1998. Basing on these results, we go further to monitor residual disease depending on the presence of aberant antigens and DNA content. The enumeration of progenitor cell CD34+ also performed for leukemia patient during the bone marrow transplantation
Hematologic Diseases ; Biological Markers

Suming up 1883 hemoglobin electrophoresis patient sample, regardless of age, suspected thalassemia and or Hb disease distributed as following: *-thal: 59.65% including-thalhomozygous: 10.43% -halhomozygous 1.20%, -thal/HbE 29.56% trait 18.46%. *HbE (HbE only and -thal/HbE) 39.66% *  thal (HbH and HbH/Hb CS) 27.25%. *HbCS: 7.47%. *  and HPFH heterozygous: 2.96%. From these results, it is necessary to up grade the test of quantification of HbA2 and simultanous develop plan of mass screening for thalasemia trait early to identify persons who are at risk of having a child with a severe disease.
Blood ; Hematologic Diseases

We performed 10 cases of autologous peripheral blood stem cell transplantation without cryoprevervation in 11/1996 and 12/1997 12. Patients were diagnosed of AML, ALL, CML and non Hodgkin’s lymphoma. The median age of the patients was 34 years (range 18-43). Peripheral blood stem cell mobilizing regiments consisted of Daunorubicine (50 mg/ m2/d, d1-d5) cytarabine and etoposide in 3 CML patients and high dose cyclophosphamide in the seven other patients, followed by G-CSF starting when an ANC< 0.5x 109/l until the day before the last leukapheresis. When a WBC count reached 4x109/l leukapheresis was started and continued for 3 consecutive days, as soon as the third collection was finished Melphalan was given as a conditioning regimen, 42 hours after giving Melphalan, the collected PSCs which were preserved at +40C (90 hours after giving Melphalan, the collected PSCs which were preserved at + 40C were reinfused through a central Hickman’s catheter. GM-CSF was given during the nadir period until the an ANC > 1x109/l for 3 consecutive days. The median number of mononucleated cells and CD34+ cell were 5x108/kg respectively. All platelet count > 20 x 109/l was 13 days and 20 days following transplantation, all patients are still in CR and alive with the median follow-up of 8 months.
Transplantation ; blood ; Hematologic Diseases

By using the test of leukocyte concentration in peripheral blood of some patients with myelodisplastic syndrome (MDS) hypoplasia/aphasia, the authors had drawn out some following: (1) The test of leukocyte concentration is valuable in the detection of immature cells in peripheral blood of patients with MDS and hypoplasia/aphasia. (2) In hypoplasia/aphasia: 28.8% of the patients have about 3.03% myeloblast and 39.7% have about 1.07% erythroblast in peripheral blood. (3) In MDS: 46.2% of the patients have 1.15% myeloblast and 61.5% of them have 1.92% erythroblast in peripheral blood.
Hematologic Diseases ; Leukocytes

The purpose of this study was to investigate the effect of He-Ne Laser irradiation on the change of some biological indicies in the experimental infected mice after 1, 3, 5, 7, 10 and 15 days of irradiation. Over 240 male mice (at the same age, weight of from 180 to 200 mg) were subjected to study and divided into 4 groups: normal and non-infected animals (group1- control1), infected animals without any treatment (group 2- control 2), infected animals treated daily by Vancocin with dose of 400 mg per kg of bodyweight (group 3) and infected animals irradiated by He - Ne Laser everday with power density of 2mW/cm2 in 10 minutes (group 4). The control and experimental animals were sacrified at 1st,3nd, 5th, 7th,10th and 15th day which were time of post- irradiation in group 4. The hematological indices, immuoparameter and piece of skin flap were evaluated. The result of experimental study showed: + After one day of irradiation: in all infected groups (2, 3, 4), skin flaps were suppurative. There was not statistically significant difference of hematological indices and immunoparameters among groups. + After 3 days of irradiation, the hematological indicies and immunoparameters increased in grop 2, 3 and 4 in comparision with group 1. However, in group 4, the number of white blood cells was smaller and immunoparameters were higher than those in group 2. In addition, the process of wound healing (epitheliazation) in group 4. This proved that Hene laser irradiation started to have effectiveness at the 3rd day of post- irradiation. + After 5-10 days of irradiation, the hematological indices and immunoparameters returned to normal levels as group1 while these indices were still high in group 2. Furthermore, the skin flaps of group4 were completely wound- healed and gradually scarred over.This illustrated that there was an early regulation of biological indices the normalisation in irradiated mice. (Group 4). + Until the 15th day, the biological indices of group 2 were just normalised.
Lasers ; Hematologic Diseases ; Animals

No abstract available.
Aged* ; Hematologic Diseases* ; Humans

Hematologic Diseases ; Humans

Hematologic Diseases ; diagnosis ; Hematologic Tests ; Humans

Epigenomics ; Hematologic Diseases ; genetics ; Humans