1.Avian Influenza and Swine Influenza:New Understanding of Crossing Species Barrier
Progress in Biochemistry and Biophysics 2006;0(05):-
This year an outbreak of influenza in Mexico comes from a new epidemic of influenza viruses:A/H1N1 influenza virus.This virus is a kind of virus mixture,including human,avian and swine influenza virus gene fragments.The pathogenic mechanism of avian,swine and human influenza virus in its natural host were compared.The main purpose is to assess the risk of which pigs and poultry has the possibility to become one of zoonotic disease and to assess the possible role in process of avian flu transmission from pigs to people.As zoonotic disease,avian influenza and swine influenza virus have the key role in the process of human infection.But the influenza virus spread of crossing species barrier is not sufficient to cause a large outbreak of human influenza.Animal influenza viruses must have a significant genetic variation before they could live for a long term in the crowd.
2.THE CLINICAL FEATURES AND DIAGNOSTIC ANALYSIS OF 30 CASES WITH REFRACTO-RY MYCOPLASMA PNEUMONIA
Modern Hospital 2015;(4):63-64,67
Objective To study the clinical features and diagnostic analysis of 30 cases with refractory myco-plasma pneumonia.Methods 60 patients with mycoplasma pneumonia treated in our hospital during 2012.03 to 2014.03 were selected, and 30 cases were diagnosed as normal mycoplasma pneumonia and the others as refractory mycoplasma pneumonia.The clinical manifestations, percentage of neutrophils, peripheral blood leukocytes , C -re-active protein (CRP) level, and chest radiographic were retrospectively analyzed , and the clinical judging indicators of refractory mycoplasma pneumonia were obtained by multivariate logistic regression analysis .Results Considering the time of fever, the difference between two groups was statistically significant (χ2 =12.27, p <0.01).The differ-ence of percentage of neutrophils , peripheral blood leukocytes and CRP between the two groups were all significant (p <0.05); Logistic regression analysis showed that time of fever >10 d, CRP >40 mg /L, appearance of large high -density lung opacities were the judging indicators of mycoplasma pneumonia refractory .Conclusion Time of fever, CRP level and imaging Findings are the judging indicators of mycoplasma pneumonia refractory .
3.Significance of Public Governance in the Construction of Supply System of Essential Drugs
China Pharmacy 2005;0(14):-
OBJECTIVE:To discuss the importance of essential drug supply system for national drug policies and the role of public governance theory in the supply of essential drugs.METHODS:In view of the status of the construction of medical insurance system in China for residents in city and countryside,some strategies for the improvement of the health service system were put forward from aspect of public governance.RESULTS:Taking service as orientation,changing the government administration to service administration,introducing non-profit organization and bringing the function of non-public ownership into full play can help improve the national essential drug policy and drug supply ensuring system and guarantee the people's accessibility to essential drugs and medication safety.CONCLUSION:It is urgent to establish the supply and marke-ting system of essential drugs.
4.Numerical analysis of the effect of capillary geometry on oxygen transport in the microcirculation by MATLAB
Journal of Medical Biomechanics 2009;24(4):263-269
Objective Delivery of oxygen in tissues is limited in the space where oxygen must diffuse between the vascular and the surrounding tissues. Normal capillaries are relatively straight and well spaced, in contrast, the tumor vascular networks usually display more irregularity and the vessel wall shows higher permeability and less elasticity. The purpose of this study was to investigate the effect of capillary elasticity and tortuosity on the oxygen distribution and make further investigation on the mechanism of the formation of hypoxic regions in tumor. Method One-dimensional capillary model was coupled with the oxygen diffusion model. Oxygen transport was investigated in a Krogh and tortuous tissue model. The capillarygeometrywas obtained bythe one-dimensional model and transferred to the tissue model. Finite element method was employed in the analysis. Result The capillary radii along the flow direction under pressures were obtained for different initial radii and the oxygen distribution in the Krogh cylinder tissue model and the model with a tortuous capillary were computed. Conclusions when the capillary radius is small, the effect of vessel elasticity may have not significant effect on the oxygen distribution. However, with the capillary radius increasing, the effect on the oxygen transport becomes obvious. Moreover, with the tortuosity of the capillary increasing, the oxygen distribution becomes more heterogeneous, which is in agreement with the result in available reference. This work will be helpful to the investigation of oxygen transport within tumor.
5.Advance in Rehabilitation of Upper Limb Function in Hemiplegic Patients after Stroke (review)
Chinese Journal of Rehabilitation Theory and Practice 2014;(4):334-339
The incidence of upper limb dysfunction of stroke patients was high, and the recovery was difficult, which seriously impact-ed their activities of daily living and quality of life. This article reviewed the new techniques and methods for hemiplegic patients after stroke. The main techniques and methods includeed bilateral isokine-matic training, mirror neuron system, gymnastics rods training, music therapy, motor imagery, upper limb rehabilitation robot, virtual reality, constraint induced movement therapy, functional electrostimulation, electromyographic biofeedback therapy, transcranial magnetic stimulation, neurophyisological therapy and so on.
7.Introduction and analysis on acupuncture education and qualification examination system in U.S.A.
Cong LU ; Wei HE ; Ying-Kai ZHAO
Chinese Acupuncture & Moxibustion 2013;33(12):1131-1134
Based on research of the Accreditation Commission for Acupuncture and Oriental Medicine (ACAOM), the National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM) and the related public websites of acupuncture educational institutions, the first hand information was studied, summarized and sorted on the status quo of the educational qualification or the relative authentication of education programs of ACAOM as well as the status of professional qualification and examination of NCCAOM. The education curriculum of the Master degree of Acupuncture, Master degree of Oriental Medicine Science as well as the Doctor degree of Acupuncture and Oriental Medicine were also introduced in this article including student enrollment and graduation in recent years. The developing tendency of the federal unified acupuncture education, management, professional qualification and examination system of U. S. A. were discussed and analyzed as well.
Acupuncture
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education
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manpower
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organization & administration
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Acupuncture Therapy
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standards
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Certification
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Humans
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United States
8.Effect of antioxidant PDTC on expression of IL-8 in human ovarian caner cell line SKOV3 in acidic environment
Kun WANG ; Manhua CUI ; Kai HE
Journal of Jilin University(Medicine Edition) 2006;0(04):-
Objective To investigate the effect of pyrrolidine dithiocarbamate (PDTC) on the proliferation and expression of IL-8 of SKOV3 cells in acid environment,and the role of nuclear factor ?B (NF-?B) in the process.Methods SKOV3 cell lines were divided into 5 groups: normal culture group,acid environment group,acid environment plus PDTC groups (25,50 and 100 mol?L-1 PDTC).All the SKOV3 cells were cultivated for 12 h.The effect of PDTC on the proliferation of SKOV3 in the acid environment was determined by MTT,the content of IL-8 protein in the culture supernatant was detected by ELISA and the expression of NF-?B protein was measured by Western blotting.Results The IL-8 expression level in the acid environment was(1 384.211?42.320) ng?L-1.there was significant difference compared with normal group(617.505 ng?L-1?47.850 ng?L-1)(P
9.Preliminary study of the accuracy of hepatic volume measurement by 3D + medical imaging visualization processing system
Cancer Research and Clinic 2017;29(8):520-523
Objective To investigate the accuracy of liver volume measurement in patients with primary hepatocellular carcinoma by using the 3D + medical imaging visualization processing system. Methods Thirty patients who were clinically diagnosed as primary hepatocellular carcinoma and underwent surgical resection before preoperative assessment were selected from January 2016 to November 2016. Preoperative thin-slice CT images were transferred into the 3D + medical imaging visualization processing system for hepatic volume measurement, the predictive resection volume were measured and statistically analyzed with that of intraoperative specimen according to water measurement method. Results All patients had complete resection of tumor, the average volume of predictive resection calculated by the 3D software was (408.84 ± 177.07) ml, the average volume of intraoperative specimen measured by the water test was (399.95 ± 176.15) ml, the difference was not statistically significant (t=1.502, P=0.144), and the average percentage error was (6.21 ± 4.73) %. Pearson correlation analysis showed that there was significant correlation between them (r=0.983, P<0.05). Conclusion 3D+medical image visualization processing system is a simple, intuitive and accurate method for liver volume measurement, which can provide the basis for the accurate measurement of liver volume and the implementation of complex hepatectomy, and guide the precise hepatectomy.
10.Treatment of complex posterior urethral strictures with urethroplasty via transpubic approach after pelvic fracture
Guoying WU ; Kai WANG ; Jinchuan HE
Chinese Journal of Trauma 2009;25(3):251-253
Objective To evaluate the efficacy and safety of urethroplasty via transpubie ap-proach in treatment of complex posterior urethral strictures after pelyic fracture. Methods Urethroplas-ty via transpubic approach was done on 26 patients (21 males and 5 females, at mean age of 26 years) with complex posterior urethral strictures. Posterior urethral stricture was 2.5-4.0 cm long in 23 patiens and > 4.0 em in three. There were five patients with urethratresia. The perioporative complications and operative effect were evaluated after the broken ends of the urethra was thoroughly resected and treated with end-to-end anastomosis. Results A follow-up for 1-7 years ( mean 4 years) showed successful op-eration in 22 patients (85%), with normal urination and without complications like osteitis pubis, pelvic disassociation, pelvic instability or urinary incontinence. But obstructed urination was found in one (4%) and failed operation in three (11%). Conclusions Urethroplasty via transpubic approach takes advantages of precise and thorough scar excision, less complications and long term curative effect and is clinically feasible and safe for patients with complex posterior urethral stricture.