Objective: To explore the factors affecting carotid plaque formation among high-risk populations for stroke, so as to provide the reference for early intervention for carotid atherosclerosis among the populations. Methods: Permanent residents were selected from Minhang District, Shanghai Municipality using the multi-staged cluster random sampling method from April to September 2021. Basic information, family history of stroke and past medical history were collected by the Community and Township Population Screening Scale for Cardiovascular and Cerebrovascular Disease Risk Factors. High-risk populations for stroke were identified according to the Technical Specifications for Stroke Screening and Prevention. Carotid plaque status was assessed using carotid ultrasonography. Factors affecting carotid plaque formation were analyzed using a multivariable logistic regression model. Results: Among the 25 666 permanent residents surveyed, 8 459 were identified as high-risk populations for stroke, including 3 362 males and 5 097 females, with a male-to-female ratio of 0.66︰1. The median age was 66.00 (quartile range, 11.00) years. Carotid plaque were detected in 4 305 cases among high-risk population for stroke, accounting for 50.89%. Multivariable logistic regression analysis showed that advanced age (OR=1.052, 95%CI: 1.043-1.061), family history of stroke (OR=1.297, 95%CI: 1.103-1.526), hypertension (OR=1.245, 95%CI: 1.025-1.512) and diabetes (OR=1.439, 95%CI: 1.241-1.669) were associated with a higher risk of carotid plaque formation in male high-risk population for stroke, advanced age (OR=1.058, 95%CI: 1.051-1.066), lack of exercise (OR=1.138, 95%CI: 1.001-1.294), family history of stroke (OR=1.201, 95%CI: 1.062-1.357), significant overweight or obesity (OR=1.269, 95%CI: 1.127-1.430) and hypertension (OR=1.169, 95%CI: 1.003-1.362) were associated with a higher risk of carotid plaque formation in female high-risk population for stroke. Conclusion The main influencing factors for carotid plaque formation among high-risk populations for stroke include age, family history of stroke, exercise, significant overweight or obesity, hypertension and diabetes, with gender differences observed.

Objective To investigate a more pedect method for a nice outward appearance of a reconstructed thumb.Methods A free one-stage plasty second toe transfer for thumb reconstruction by interchanging the whole skin-nail flap from the great toe with another one from the second toe.Results There were 12 cases in this group,following-up 6-9 months in 8 cases,7 cases was excellent and 1 cases was good.The reconstructed thumb got a nice looking and more normal function while no blight to the great toe occurred.Conclusion It is an effective new procedure in ameliorating outward appearance of the reconstructed thumb by transferring the free moulded second toe.

Objective:To systematically analyze the impact of PM 2.5 exposure on children′s behavior. Methods:Use air pollution, fine particulate matter, children, students, child behavior, neurobehavior, attention, autism, autism spectrum disorder, attention deficit hyperactivity disorder, hyperactivity, and bad behavior as Chinese keywords. Use air pollution, fine particulate matter, particulate matter, PM 2.5, children, student, behavior, autism, attention, intention, neurobehavior, attention deficit hyperactivity disorder, ADHD, ASD as English keywords. Journal papers and grey literature were searched from CNKI, Wanfang Data Knowledge Service Platform, PubMed and Web of Science database from their inception to Nov 2019, which are related to PM 2.5 and children behavior problems. The search period is as of November 2019, and the languages are limited to Chinese and English. The inclusion criteria included the exposure factor of the study as PM 2.5; the results of the study included behavioral disorders and related diseases; the languages of the included literature were Chinese and English; original research papers; case-control, cohort or cross-sectional studies. Exclusion criteria include animal experiments; repeated reports; review articles; research exposure factors do not include PM 2.5; children self-harm and illegal behaviors. Finally, 25 articles were included. Results:Among the 25 included articles, 12 studies discussed the relationship between PM 2.5 exposure and childhood behavioral disorders, 13 discussed the relationship between PM 2.5 exposure and abnormal behaviors in children, and 5 studies based on the Chinese population. According to the research design, it is divided into birth cohort studies (15), cross-sectional studies (5), and case-control studies (5). China mainly uses cross-sectional studies and case-control studies. The results of the study suggest that PM 2.5 exposure will increase the risk of children′s behavioral problems, with both short-term and long-term effects. Short-term exposure to PM 2.5can easily cause mild abnormal behaviors in children, and long-term exposure may increase the risk of children′s behavioral disorders. The fetal period and the infant period may be the key exposure window for the occurrence of children′s behavior problems. Conclusion:There may be a certain correlation between PM 2.5 exposure and children′s behavioral problems. In future studies, longitudinal cohort studies should be carried out to enhance the causal relationship between fine particulate matter pollution and children′s behavioral problems.

Objective:To systematically analyze the impact of PM 2.5 exposure on children′s behavior. Methods:Use air pollution, fine particulate matter, children, students, child behavior, neurobehavior, attention, autism, autism spectrum disorder, attention deficit hyperactivity disorder, hyperactivity, and bad behavior as Chinese keywords. Use air pollution, fine particulate matter, particulate matter, PM 2.5, children, student, behavior, autism, attention, intention, neurobehavior, attention deficit hyperactivity disorder, ADHD, ASD as English keywords. Journal papers and grey literature were searched from CNKI, Wanfang Data Knowledge Service Platform, PubMed and Web of Science database from their inception to Nov 2019, which are related to PM 2.5 and children behavior problems. The search period is as of November 2019, and the languages are limited to Chinese and English. The inclusion criteria included the exposure factor of the study as PM 2.5; the results of the study included behavioral disorders and related diseases; the languages of the included literature were Chinese and English; original research papers; case-control, cohort or cross-sectional studies. Exclusion criteria include animal experiments; repeated reports; review articles; research exposure factors do not include PM 2.5; children self-harm and illegal behaviors. Finally, 25 articles were included. Results:Among the 25 included articles, 12 studies discussed the relationship between PM 2.5 exposure and childhood behavioral disorders, 13 discussed the relationship between PM 2.5 exposure and abnormal behaviors in children, and 5 studies based on the Chinese population. According to the research design, it is divided into birth cohort studies (15), cross-sectional studies (5), and case-control studies (5). China mainly uses cross-sectional studies and case-control studies. The results of the study suggest that PM 2.5 exposure will increase the risk of children′s behavioral problems, with both short-term and long-term effects. Short-term exposure to PM 2.5can easily cause mild abnormal behaviors in children, and long-term exposure may increase the risk of children′s behavioral disorders. The fetal period and the infant period may be the key exposure window for the occurrence of children′s behavior problems. Conclusion:There may be a certain correlation between PM 2.5 exposure and children′s behavioral problems. In future studies, longitudinal cohort studies should be carried out to enhance the causal relationship between fine particulate matter pollution and children′s behavioral problems.

Evaluate the effect of the fresh air purification system on the improvement of indoor PM 2.5 levels in a primary school classroom in Jinan City, Shandong Province. Our purpose is to explore the optimal operating time of the fresh air system and the main factors that affect the fresh air purification system to improve indoor air quality. From December 9, 2019 to December 10, 2019, two classrooms of the same area on the third floor of a primary school building in Jinan City, Shandong Province were selected as monitoring points. During the operation of the fresh air purification system, the PM 2.5 concentration in the classroom is reduced by an average of 48.1%-61.5% compared to the outdoor PM 2.5 concentration. After running for about 2 hours, the indoor PM 2.5 concentration decreased to a relatively stable concentration level. The operating time of the fresh air purification system, student activities between classes, indoor temperature, indoor relative humidity, and outdoor PM 2.5 concentration are important factors that affect the indoor particulate removal rate. In the case of a certain amount of fresh air and indoor area, closing doors and windows and appropriately extending the operation time of the fresh air purification system can improve the air quality in the classroom to a certain extent and protect the health of students.

Evaluate the effect of the fresh air purification system on the improvement of indoor PM 2.5 levels in a primary school classroom in Jinan City, Shandong Province. Our purpose is to explore the optimal operating time of the fresh air system and the main factors that affect the fresh air purification system to improve indoor air quality. From December 9, 2019 to December 10, 2019, two classrooms of the same area on the third floor of a primary school building in Jinan City, Shandong Province were selected as monitoring points. During the operation of the fresh air purification system, the PM 2.5 concentration in the classroom is reduced by an average of 48.1%-61.5% compared to the outdoor PM 2.5 concentration. After running for about 2 hours, the indoor PM 2.5 concentration decreased to a relatively stable concentration level. The operating time of the fresh air purification system, student activities between classes, indoor temperature, indoor relative humidity, and outdoor PM 2.5 concentration are important factors that affect the indoor particulate removal rate. In the case of a certain amount of fresh air and indoor area, closing doors and windows and appropriately extending the operation time of the fresh air purification system can improve the air quality in the classroom to a certain extent and protect the health of students.