OBJECTIVE To explore administrative measures in preventing infection.for reducing the cross infection during bronchoscopy. METHODS The hidden infection during sterilizing the bronchoscopes was analyzed and the measures of preventing infection were provided. RESULTS By taking standardized management to avoid the cross infection,the quality of medical treatment and nursing was raised and ensured the safety of patients and medical staff. CONCLUSIONS It plays an important role on the control of nosocomial infection with the establishment of the strict protecting measures and sterilizing procedures.