0 05) CONCLUSION:The two products of valaciclovir tablet are bioequivalent

Objective:To study a new positioning method of elbow external fixation rotation axis,and to evaluate its feasibility.Methods:Four normal adult volunteers and six Sawbone elbow models were brought into this experiment.The kinematic data of five elbow flexion were collected respectively by opti-cal positioning system.The rotation axes of the elbow joints were fitted by the least square method.The kinematic data and fitting results were visually displayed.According to the fitting results,the average moving planes and rotation axes were calculated.Thus,the rotation axes of new kinematic methods were obtained .By using standard clinical methods,the entrance and exit points of rotation axes of six Sawbone elbow models were located under X-ray.And The kirschner wires were placed as the representatives of rotation axes using traditional positioning methods.Then,the entrance point deviation,the exit point de-viation and the angle deviation of two kinds of located rotation axes were compared.Results:As to the four volunteers,the indicators represented circular degree and coplanarity of elbow flexion movement tra-jectory of each volunteer were both about 1 mm.All the distance deviations of the moving axes to the ave-rage moving rotation axes of the five volunteers were less than 3 mm.All the angle deviations of the mo-ving axes to the average moving rotation axes of the five volunteers were less than 5 °.As to the six Saw-bone models,the average entrance point deviations,the average exit point deviations and the average angle deviations of two different rotation axes determined by two kinds of located methods were respective-ly 1.697 2 mm,1.838 3 mm and 1.321 7°.All the deviations were very small.They were all in an ac-cep-table range of clinical practice.Conclusion:The values that represent circular degree and coplanari-ty of volunteer's elbow single curvature movement trajectory are very small.The result shows that the elbow single curvature movement can be regarded as the approximate fixed axis movement.The new method can replace the traditional method in accuracy.It can make up the deficiency of the traditional fixed axis method.

Objective To investigate the alignment of the elbow after Coonrad-Morrey (CM) total elbow arthroplasty (TEA),and to establish normal radiographic parameters correlated with prosthesis design in Chinese adults,as well as to detect whether CM prosthesis fits for Chinese.Methods Forty-two healthy volunteers were recruited and underwent radiographs of bilateral elbows in a standardized anterior-posterior (AP) fashion.Furthermore,99 AP radiographs of normal elbows and 54 AP radiographs of elbows after CM TEA were both collected from Picture Archiving and Communication System.The following radiographic parameters were measured:humerus-elbow-wrist (HEW) angle,the angle between the axis of humerus medullary cavity and the hinge axis of elbow (H-H angle),the angle between the axis of middle ulna medullary cavity and the hinge axis of elbow (MU-H angle),the angle between the axis of proximal ulna medullary cavity and the hinge axis of elbow (PU-H angle),the horizontal distance between the axis of humerus medullary cavity and the axis of proximal ulna medullary cavity (medullary translation).The differences in above parameters between normal elbows and elbows after CM TEA were compared.For normal elbows,the radiographic differences between male and female and that between right and left were analyzed,as well as the correlation with height.Results HEW angle (2.71°±8.08°) and medullary translation (1.79±3.49 mm) in patients after CM TEA were significantly less than that in normal (11.30°±7.21°,5.25±2.55 mm respectively),while H-H angle (89.92°±3.64°),MU-H angle (93.34°±6.30°) and PU-H angle (78.87°±4.79°) were significantly larger than that in normal (87.59°±5.62°,89.23°±5.66°,76.22°±4.69° respectively).The right HH angle of female was significantly larger than that in male.There were no significant difference in other parameters between male and female,and between right and left.All of the correlations between these parameters and height were not significant.Conclusion Elbow valgus decreases and forearm translates laterally after CM TEA in Chinese patients.Currently,the CM prosthesis can theoretically cause decreasing elbow valgns and lateral translation of forearm.