1.A review of evaluation scales for therapeutic effect of cervical spondylotic radiculopathy.
Feng SHENG ; Guoquan SHEN ; Wuquan SUN
Journal of Integrative Medicine 2010;8(9):824-8
Abstract: Various kinds of therapies have been clinically applied to treat cervical spondylotic radiculopathy (CSR). However, the evaluation standards of therapeutic effect in different medical institutions are quite different from each other at present, thus bringing about many difficulties in the therapeutic effect evaluation of CSR treatment. Although many CSR-related scales have been developed, none of them could completely represent or reflect the exact curative actualities of CSR in China. Therefore, it is quite essential to establish a comprehensive evaluation scale for the therapeutic effect of CSR. And such evaluation system, in which the estimation of quality of life should be included, will become the developmental direction of CSR research in future.
2.The curative effects of using oxygen treatment combined mixture to bedsore
Aihua JIAN ; Guoquan LUO ; Biqiang SHEN ; Minxi HUANG
Chinese Journal of Practical Nursing 2006;0(18):-
ObjectiveTo study the curative effects of using oxygen treatment combined mixture to Ⅲ-Ⅳ bedsore. Methods Divided 63 patients into the observation group (32 cases) and the traditional group (31 cases) randomly. Oxygen treatment combined mixture was used in the observation group and the traditional nursing measures were used in the traditional group. Compared the curative effects of bedsore between the 2 groups.Results The cure rate of Ⅲ-Ⅳ bedsore in the observation group was significant higher than that of in the traditional group,P
3.The effects of tuina on muscle atrophy and muscle satellite cell proliferation after denervation
Rubao GUO ; Juntao YAN ; Xilin ZHANG ; Guoquan SHEN
Chinese Journal of Physical Medicine and Rehabilitation 2013;(4):261-264
Objective To observe the effects of tuina on muscle atrophy after denervation and on muscle satellite cell proliferation.Methods Ninety male rabbits with denervated skeletal muscles were randomly divided into a normal group,a control group,and a treatment group.Tuina was applied daily to the right gastrocnemius muscles beginning one day after the modeling.Changes in muscle wet weight ratio and the amount of skeletal muscle satellite cells (SCs) were observed 1,2 and 3 weeks and 1,2,4 and 6 months post-modeling.Results The muscle wet weight ratios of both the treatment group and the control group were lower than those of the normal group.The weight ratio in the treatment group was significantly different from that in the control group after 2 months (0.578 ±0.163 vs 0.470 ±0.062),4 months (0.575 ±0.110 vs 0.453 ±0.101) and 6 months (0.559 ±0.083 vs 0.446 ±0.048).The amount of SCs was also significantly different in the treatment and control groups after 1 week (16.83 ±5.31 vs8.67±2.58),2 weeks (51.83±7.94 vs32.00±6.93) and4 months (11.17±3.49 vs 17.67±4.18).Conclusion Tuina therapy can promote proliferation of satellite cells and delay the atrophy of denervated skeletal muscles.
5.Action of Tuina on Retro-positioning of Skull Spatial Offset in Patients with Cervical Vertigo
Jiarong WU ; Min FANG ; Jun HU ; Guoquan SHEN ; Shuyun JIANG
Journal of Acupuncture and Tuina Science 2008;6(2):83-86
Objective:To investigate the onset mechanism of cervical vertigo from the proprioceptive sensation and provide clinical basis for its treatment.Methods:Among the 121 cases that conformed to the diagnostic criteria of cervical vertigo,70 cases who presented with negative neck-rotation test and cervical vertigo without obvious vascular factors by transcranial Doppler(TCD)were assigned to the observation group,while 51 cases who presented with positive neck-rotation test and cervical vertigo due to spasm of vertebral basal artery or insufficient blood supply by TCD were assigned to the control group.The cases in the two groups were treated once every day,5 days make up one treatment course and the resuIts were statistically analyrzed after one treatment course.Results:The skull triaxial spatial offset of the cases in the two groups were significantly reduced after the treatment (P<<0.01).However, there was no statistically significant difference between the skull triaxial spatial offset between the two groups (p>0.05).It is not conclusive that the therapeutic effect in the two groups was significantly different after one treatment course.Conclusion:Tuina manipulation therapy can improve the skull spatial ofrset repositioning ability of the Patients.
6.Mechanisms of Spinal Micro-adjustment Manipulations in Treating Cervical Spondylotic Radiculopathy
Guomiao ZHU ; Wuquan SUN ; Guoquan SHEN ; Min FANG ; Yuanchun XIAO
Journal of Acupuncture and Tuina Science 2007;5(2):68-70
On the basis of the investigation of the pathogenesis of cervical spondylotic radiculopathy, this paper studies the mechanisms of spinal micro-adjustment manipulations in recovering and improving cervical dynamic and stationary balance from the perspective of biomechanics.
7.Clinical Observation of Tuina Techniques in Treating Muscular Torticollis in 33 Infants
Zhiwei CHEN ; Guoquan SHEN ; Min FANG ; Yuanchun XIAO
Journal of Acupuncture and Tuina Science 2004;2(4):60-62
Thirty-three infants with muscular torticollis were treated by Tuina techniques, and the size of the hardened sternocleidomastoid muscle in the affected side was B-ultrasonographically observed before and after treatment. Results: 27 cases were cured, 5 cases got effectiveness, 1 case failed and the total effective rate was 97.0%; B-ultrasonography, in the palpable cord-like or ovary-like lumps,showed low echo in 28 cases, moderate echo in 2 cases and high echo in 3 cases; there were significant differences in the length, thickness and width of the lumps between before and after treatment, P<0.01. It is indicated that Tuina is quite effective against infantile muscular torticollis; that ultrasonography can be adopted as an objective item for the evaluation of the clinical efficacy of Tuina in the treatment of infantile muscular torticollis, and it is a simple, convenient and inexpensive method and should be extensively popularized in clinical practice.
8.Quantitative determination of limonin in traditional Chinese medicine by LC-MS/MS
Gangyi LIU ; Guoquan WANG ; Hui ZHANG ; Chen YU ; Shen JI ; Dayuan ZHU ;
Chinese Traditional Patent Medicine 1992;0(02):-
Objective: To develop a simple LC MS/MS method for the measurement of limonin in fructus evodiae, cortex phellodendri, cortex dictamni and its preparation. Methods: Separation was obtained by using a discovery C 18 column (150mm?2.1 mm), The mobile phase:A:water-0.1%HAc;B:acetonitrile-0.1%HAc;The elution program was gradient and the flow rate was 0.2mL?min -1 . The mass detector was set MS1(IS)=187.0 and MS2(Limonin)=471.0 by multiple reaction monitor(MRM) respectively.The sample was added psoralen(IS), then extracted with methanol chloroform(1∶3).Results: Limonin was linear from 25 to 1000ng?mL -1 ( r = 0.9996), The regression equation was C=3.124 As/Ai 1.935?10 -3 . The average recovery was 100.2%.Conclusion: This method is simple, quick, sensitive and exclusive.
9.Clinical observation of the therapeutic effect of spine fine adjusting in treating cervical spondylotic radiculopathy and the conversion of cervical curvature
Wuquan SUN ; Xianfei XIE ; Jiaqin WANG ; Cen ZHONG ; Guoquan SHEN ; Min FANG ; Guomiao ZHU ; Li GONG ; Jie ZHANG ; Xilin ZHANG ; Lequn ZHU
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective:Discuss and analyze the mechanisms of spine fine adjusting through the observation of the therapeutic effect in treating cervical spondylotic radiculopathy(CSR)and the conversion of cervical curvature.Methods: Randomly divide 106 CSR patients into two groups–manipulation therapy group and traction therapy group,53 for each.Judge the therapeutic effect by evaluation scales and measure the cervical curvature on X-ray photographs.Results:The symptoms and physical signs of the patients in both two groups have been improved(P
10.Capillary blood flow with dynamical change of tissue pressure caused by exterior force.
Yufeng LIU ; Shixiong XU ; Juntao YAN ; Guoquan SHEN ; Wuquan SUN ; Y CHEW ; H LOW ; Jun XU
Journal of Biomedical Engineering 2004;21(5):699-703
A hemodynamic model of capillary and tissue, in which tissue pressure changed with swing manipulation of Traditional Chinese Medical Massage (TCMM), is presented in this paper to explain the hemodynamic mechanism of swing manipulation. Blood flowed in capillary with low Reynolds number. Plasma exuded through capillary according to the Starling's Law. Tissue pressure changed linearly with the massage force measured. Blood apparent viscosity, plasma protein concentration and red cell's hematocrit were taken into account. Capillary flow rate, blood apparent viscosity, filtration rate and filtration fraction with dynamical change of tissue pressure were calculated numerically, and were compared with those in static tissue pressure condition. Results showed that, dynamical change of tissue pressure led to the increase of capillary flow rate and the decrease of blood apparent viscosity, which qualitatively explained the hemodynamic mechanism of "promoting blood circulation and removing blood stasis" in swing manipulation of TCMM.
Biomechanical Phenomena
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Blood Flow Velocity
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Blood Viscosity
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Capillaries
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physiology
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Hematocrit
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Hemodynamics
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Humans
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Massage
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Models, Cardiovascular
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Pressure
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Regional Blood Flow