Objective To discuss the strategies of lower complications of LC in the initial stage. Methods The clinical data of 168 patients,from Sep. 2008 to May. 2010 ,treated with laparoscopic cholectectomy were retrospectively analyzed. Results LC was performed in all patients(100%). None of the series had intra-abdominal bleeding,biliary tract injury and no other serious complications were observed. Conclusion Through correct perioperative management and meticulous operation, LC was safe and complications lower in the initial stage.