1.Discussion of "Brain Controls Mental and Emotional Activities" in Sheng Ji Zong Lu
Journal of Zhejiang Chinese Medical University 2006;0(04):-
The theory basis for 'nao zhe wu you suo shou ming' is expounded based on the time background for Sheng Ji Zong Lu,the deeper realization of brain anatomy and pathophysiology.'Brain Controls Mental and Emotional Activities' theory is the result of self-development of traditional Chinese medicine and recreation of theory.It might change the current situation of ' the heart replaces the brain ' and make a real qualitative leap in the theory for the brain and the spinal cord in traditional Chinese medicine.
2.Methodology and theory study of relating Chinese materia medica to brain and channel tropism
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
To expound evidence and methodology of relating Chinese materia medica to brain and channel tropism.Evidences of traditional Chinese medical are: correlative medicine,visceral system and channel system recorded in literature.Modern medicine study has found the meridian distribution theory has close relation with blood brain barrier,effective constituents' distribution in the body,receptor theory,cylic nucleotides,and brain protection and so on.It provids reference for future research of relating Chinese Medicine to brain and channel tropism.
3.The comparision between the medical malpractice and the medical accident
Chinese Medical Ethics 1994;0(06):-
Distinguish between the medical accident and the medical malpractice and the definitude of their responsibility, are propitious to solve and mitigate the conflict between the doctors and the patients. The text compares the medical accident with the medical malpractice, from their definition, elements and respond.
4.Ensuring the Realization of the Patients’ Informed Consent Right
Chinese Medical Ethics 1995;0(02):-
Respecting patients' informed consent right is not only the request of both patients and society,but it is the duty of law and ethics as well.Hospitals should respect the freedom of patients,fulfill the duty of caring and informing,and combine the adjustment of law and moral.
5.Humanistic spirit in evidence-based medicine and harmonious doctor-patient relationship
Guoqing ZHENG ; Jinzhang ZHANG
Chinese Journal of Hospital Administration 2010;26(3):230-232
Evidence-based medicine mirrors the natural and social properties of human being,harmoniously integrating scientific spirit and humanistic spirit. Discussions were made on such aspects as the relationship between human spirit and harmonious doctor-patient relationship. The humanistic spirit of evidence-based medicine, and the humanistic spirit of evidence-based medicine as used in building harmonious doctor-patient relationship. The authors point out the following: 1) Medical science itself is a wealth of humanistic sprits, and medicinal science can better serve human being with humanistic spirit;2) Evidence-based medicine is completely in line with medical humanities, which scientifically reveals the "People-oriented medicine" as the essential attribute of human sciences;3) Modem clinical medicine has unveiled the evidence-based era. Based on these findings, the authors hold that in such an era,exploration and understanding of the human spirit as the core of evidence-based medicine and focusing on the cultivation of medical humanistic spirit, will be conducive to building a harmonious doctor-patient relationship.
6.Influence of Nao Xue Kang tablet on dynamic expression of PAR- 1after acute intracerebral hemorrhage in rats
Guoqing ZHENG ; Yan WANG ; Xiaotong WANG
Chinese Journal of Pathophysiology 2006;22(4):786-790
AIM: To study the dynamic expression of protease - activated receptors - 1 (PAR- 1 ) after intracerebral hemorrhage (ICH) and the influence of Nao Xue Kang Tablet (NXKT) on it's expression. METHODS: 72 Wistar rats were divided into normal group, ICH model groups (ICH, 6 h, 24 h, 3 d, 7 d), Nao Xue Kang groups (NXKT, 6 h, 24 h, 3 d,7 d).ICH models were produced with the induction of collagenase typeⅦ - S, except normal group. Immunohistochemical method was used to detect PAR- 1 protein and RT- PCR technique was used to detect PAR- 1 mRNA in brain tissues around the haematoma at different time points of different groups. RESULTS: PAR - 1 protein and mRNA were mildly positive in normal group. In ICH model groups, intensity of PAR - 1 expression started to increase at 6 h, and further increased at 24 h. PAR - 1 expression reached the peak at 3 d and began to descend. At 7 d the decent was obvious. At 6 h, 24 h, 3 d, and 7 d time points, the PAR-1 protein positive cell number and PAR- 1 mRNA absorbance ratio in ICH model and NXKT groups were significantly higher than those in normal group ( P <0.05 or P < 0.01). The PAR- 1 protein positive cell number and PAR- 1 mRNA absorbance ratio in NXKT group were significantly lower than in ICH model group ( P < 0.05 or P < 0.01 ). CONCLUSION: After ICH,PAR - 1 is continuously activated because of the stimulation of thrombin. Action of thrombin after ICH may be mediated by PAR- 1; NXKT may inhibit the activation of PAR- 1, so the praxiology is improved. This may be one of the main mechanisms that NXKT could facilitate the recovery of nervous function.
7.Assay of Correlative Oncogene of Testicular Tissues in Cryptorchids
Guoqing LIU ; Lixuan WANG ; Wei ZHENG
Journal of Chinese Physician 2000;0(12):-
The P53,Rb,nm23,C-berB-2 genes of testicular tissues were assayed with immunohistochemical method in 30 hereditary cryptorchids.The results indicate that nm23 of 4 cases and C-berB-2 of 2 cases were positively stained in 30 cases,and one of the 6 cases was both positively stained in an abdominal undescended testis.The findings suggest that aberrantion of nm23,C-berB-2 genes is associated with testicular neoplasms of retained testis,specifically abdominal undescended testis has trend to variation of correlative oncogenes of testicular tissues.
8.Influence of Nao Xue Kang tablet on dynamic expression of PAR-1 after acute intracerebral hemorrhage in rats
Guoqing ZHENG ; Yan WANG ; Xiaotong WANG
Chinese Journal of Pathophysiology 1986;0(04):-
AIM: To study the dynamic expression of protease-activated receptors-1 (PAR-1) after intracerebral hemorrhage (ICH) and the influence of Nao Xue Kang Tablet (NXKT) on it's expression. METHODS: 72 Wistar rats were divided into normal group, ICH model groups (ICH, 6 h, 24 h, 3 d, 7 d), Nao Xue Kang groups (NXKT, 6 h, 24 h, 3 d,7 d). ICH models were produced with the induction of collagenase typeⅦ-S, except normal group. Immunohistochemical method was used to detect PAR-1 protein and RT-PCR technique was used to detect PAR-1 mRNA in brain tissues around the haematoma at different time points of different groups. RESULTS: PAR-1 protein and mRNA were mildly positive in normal group. In ICH model groups, intensity of PAR-1 expression started to increase at 6 h, and further increased at 24 h. PAR-1 expression reached the peak at 3 d and began to descend. At 7 d the decent was obvious. At 6 h, 24 h, 3 d, and 7 d time points, the PAR-1 protein positive cell number and PAR-1 mRNA absorbance ratio in ICH model and NXKT groups were significantly higher than those in normal group (P
9.LONG-TERM SURVIVAL ANALYSIS OF 36 WILMS' TUMOR PATIENTS AFTER COMBINED MODALITY THERAPY
Guoqing HU ; Jinxiang YANG ; Zuan ZHENG
Chinese Journal of Radiation Oncology 1992;0(04):-
From 1965 to 1986, 36 patients with Wilms' tumor were terated by nephrectomy,postoperative irradiation and chemotherapy. The radiation doses of 1540~3920cGy were given according to an age-medulated dose scheme. All except 4 Stage I received chemotherapy. The most commonly used chemotherapeutic agent was Act-D, VCR. The overall 5-year survival rate was 61.1%(22/36) and 10-year survival rate was 56%(14/25). The 5- and 10-year survival rates were 87.5% and 80% for Stage I, 63.2% and 61.5% for stage II,33.3% and 28.6% for stage III patents. The favorable factors which led to better results were: early stages(stages I,II) and aged under 5 years . The 5-year survival rates of Stages I,II and Stage III were 70.4%(19/27) and 33.3%(3/9), respectively(P
10.Video-assisted thoracoscopic surgery for traumatic hemothorax
Min ZHENG ; Guoqing HU ; Ye XU
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To evaluate the application of video-assisted thoracoscopic surgery (VATS) in the treatment of traumatic hemothorax. Methods We performed VATS in 60 cases of traumatic hemothorax with medium amount of bleeding or above from March 2000 to March 2004, including 12 cases accompanying the prodrome of shock and 6 cases associated with injuries of liver or spleen. Unilateral VATS was carried out in 48 cases, all of which were completed under thoracoscope except 3 cases of heart injuries were supplemented with mini-incision repair. Bilateral VATS was conducted in 6 cases and the combination of thoracoscopy with laparoscopy was required in 6 cases. Results The operation time was 45~175 min (mean, 105 min) and the postoperative hospital stay was 7~13 days (mean, 11 days). No complication occurred. Conclusions VATS in the management of traumatic hemothorax is safe, effective and minimally invasive, with a relatively short operation time and quick recovery.