1.Meta analysis on T cell subsets of patients with severe acute respiratory syndrome
Chinese Journal of Immunology 1985;0(02):-
Objective:Analyzing on T cell subsets of patients with severe acute respiratory syndrome.Methods:Indexed thesis for T cell subsets of patients with severe acute respiratory syndrome.Big sample data was synthesized in these thesis.The data were analyzed with RevMan4.2 analysis software.Results:SARS patients in initial stages and progressive stages(14 d) when they were compared with patients in initial stages and progressive stages patients(
2.Relationship of operation time point with therapeutic effect in central cervical spinal cord injury syndrome
Yi YE ; Guoqiang JIANG ; Liming CHENG
Chinese Journal of Trauma 2014;30(4):320-323
Objective To evaluate the correlation of interval from injury to surgery with outcome for central cervical spinal cord injury syndrome.Methods A retrospective analysis was done for 31 patients with central cervical spinal cord injury syndrome treated surgically between March 2007 and March 2011.According to the timing of surgical intervention,the patients were divided into early operative group (<7 days from injury,n =14) and late operative group (≥7 days from injury,n =17).Japanese Orthopedic Association (JOA) score on admission,at postoperative half-year and at final follow-up were recorded and compared between the two groups.JOA recovery rate was determined and analyzed for correlation with operation time point.Results Mean follow-up was (16.1 ± 4.5) months (range,12-25 months).All patients had different degree of neurological recovery.JOA recovery rate in early operative group was apparently better than that in late operative group at final follow-up (P < 0.01).JOA recovery rate at follow-up was negatively correlated with intervals between injury and surgery (r =-0.763,P < 0.01).Conclusion For patients with central cervical spinal cord injury syndrome,time from injury to surgery is negatively correlated with outcome,indicating that early surgery may be associated with better outcomes.
3.Determination of Malondialdehyde Level and XanthineOxidase and Antioxidases Activity inScalding-injured Rats
Shangyu YE ; Deqing WANG ; Guoqiang LU
Journal of Third Military Medical University 1984;0(02):-
The back of rats was immersed in 95℃ water for 10 seconds to produce 10% and 30% TBSA full thickness burn injury. Malondialdehyde (MDA) level in plasma, erythrocytes, the liver and the lungs, the activity of superoxide dismutase (SOD), glutathione peroxidase (GSSG-Px), and catalase (CAT) in the blood, liver and lungs, and the activity of liver xanthine oxidase (XO) were determined 4 hours postburn. It was found that MDA level and SOD activity in rat tissues, XO and CAT activity in the liver, and GSSG-Px activity in the lungs and blood increased significantly aftfe injury. The severity of these changes positively correlated with the area of scalding except the SOD activity in the liver and lungs which showed no significant difference in those animals with 10% and 30% TBSA scalding. However the CAT activity in the blood and lungs decreased postburn and the liver GSSG-Px activity in 10% and 30%TBSA scalding-injured rats was higher and lower than that of the control respectively.The results imply that when scalding involves less area of body surface, the function of anti-peroxidation system of the body will be enhanced by inducing the synthesis of antioxidases; when severe scalding covers larger body surface, the induction of enzyme synthesis will be deficient in some tissues of the body.
4.Comparison of growth and apoptosis of fibroblasts derived from kidneys with and without interstitial fibnwis
Guoqiang ZHENG ; Rengao YE ; Yongxinng CHENG
Chinese Journal of Nephrology 1994;0(02):-
Objective To study the role of fibroblasts in the pathomechanisms of renal interstitial fibrosis(RIF). Methods Growth behavior and apoptos, of renal interstitial fibroblasts in cultures, established using renal biopsies of casts with and without RIF, were studied. Results There were significant alterations in the growth behavior, the differentiation pattern of potentially mitotic fibroblast populations and programmed cell death in cultures derived from kidneys with RIF, as compared with cultures of normal origin. Conclusion The abnormal growth and apoptosis of fibroblasts may play an im-portant role in RIF. Inhibiting the proliferation and promoting the programmed death of fibroblasts may be benificial to patients with RIF.
5.Systematic Review of the Correlation between Periodontal Disease and Coronary Heart Disease
Juan GENG ; Guoqiang HU ; Fangli YE
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(01):-
0.05. Fixed effect model analysis showed that the summary RR was 1.43 (95%CI, 1.36 to 1.90), indicating a higher risk of future coronary heart disease in individuals with periodontal disease compared with those without. Conclusion This result suggests that periodontal disease is significantly related with coronary heart disease, they may be a risk indicator for each other. However, we should strengthen the prevention and cure of PD and control the probability of CHD.
6.Clinical Observation of External Application of Wentong Paste Plus Local Block Therapy for Treatment of Stenosing Tendovaginitis at Radial Styloid
Zhihao LIAO ; Xi CHEN ; Xueru WU ; Guoqiang YE
Journal of Guangzhou University of Traditional Chinese Medicine 2017;34(4):526-530
Objective To observe clinical curative effect of the external application of Wentong Paste plus local block therapy for the treatment of stenosing tendovaginitis at radial styloid. Methods A total of 108 cases of patients with stenosing tendovaginitis at the radial styloid were randomly divided into local block therapy group, combination group and Wentong Paste group, 36 cases in each group. The local block therapy group was given injection of blocking liquid into the tendon sheath, combination group was given external application of Wentong Paste(mainly composed of Radix Angelicae Sinensis, Fructus Psoraleae, Radix Angelicae Pubescentis, and Rhizoma et Radix Notopterygii) plus local block therapy, and Wentong Paste group was only given external application of Wentong Paste. Before treatment and after treatment for one and 2 week(s), visual analogue scale (VAS) scores of pain and range of motion (ROM) of wrist joint were observed for the evaluation of clinical effectiveness and safety. The patients were followed up for 3 months for the assay of recurrence rate. Results (1) After treatment for one week, the total effective rate of local block therapy group, combination group and Wentong Paste group was 77.8%, 100.0%, 72.2%respectively, and the total effective rate after treatment for 2weeks was 86.1%, 100.0%, 86.1% respectively. The combination group had better clinical efficacy than local block therapy group and Wentong Paste group (P < 0.05). (2) After treatment for one and 2 week (s), VAS scores of the 3 groups were obviously increased while ROM was much increased (P < 0.05 compared with those before treatment). The combination group had the lowest VAS scores and highest ROM(P < 0.05).(3) No adverse reaction was found in the 3 groups during the treatment. (4) The 3 month follow-up results showed that the recurrence rate of the three groups was 30.61%, 10.20%, 20.41% respectively, and the combination group had the lower rate than local block therapy group and Wentong Paste group(P<0.05). Conclusion The external application of Wentong Paste plus local block therapy is effective for the treatment of stenosing tendovaginitis at radial styloid by relieving pain, increasing the ROM, and reducing the recurrence rate. The one-week efficacy of Wentong Paste alone was inferior to that of local block therapy alone, but their two-week efficacy showed no obvious difference. Moreover, Wentong Paste has an obvious advantage in reducing the recurrence rate.
7.Cystitis and obstructive uropathy in systemic lupus erythematosus: a case report and literature review
Hongwei ZHANG ; Guoqiang CHEN ; Meixin YAN ; Peiyi YE
Chinese Journal of Rheumatology 2002;0(03):-
Objective To enhance the understanding of cystitis, obstructive uropathy (OU) and chronic intestinal pseudo-obstruction (CIPO) in systemic lupus erythematosus (SLE). Methods We presented a case of SLE complicated with cystitis, OU and CIPO, and reviewed relevant English and Chinese literature. Results The case was a 37 year-old female with a history of SLE for 4 years. She developed urinary irritant symptoms for 1 year and abdominal distention for 1 month before admission. Ultrasound and cystoscopic studies revealed a thickening of bladder wall and reduced bladder volume; cystoscopic study revealed inflammatory and edematours mucosa; Ultrasound study and X-ray image confirmed the existence of OU and CIPO. Symptoms of urinary irritant and CIPO were relieved after initiation of prednisone and cyclophosphamide (CTX), but reducing the dosage of prednisone and CTX had caused a relapse. Conclusion Cystitis is a rare clinical manifestation of SLE, it is likely to be misdiagnosed. The pathological change of cystitis complicated with SLE is interstitial cystitis and is the most common cause of OU in SLE. OU is closely related to CIPO and it is suggested that patients with these complications may be classified as a unique subgroup of SLE. Intestinal obstruction is a severe complication of SLE with high mortality rate, clinicians should be aware of this unique subgroup of SLE and treat it properly.
8.Vision and realization of field portable first-aid unit
Guoqiang YU ; Yongxiong YE ; Ming ZENG ; Fanghua JIN
Chinese Medical Equipment Journal 1989;0(02):-
In landing phase, there would be a severe conflict between too many wounded soldiers at field and the shortage of immediate rescue. To solve that problem and according to the principle of "Keep up, Carry out, and Bring off ", a set of field portable first-aid unit has been developed to improve the rescue ratio of the field wounded soldiers.
9.Theraputical effect of Mammotome vacuum biopsy system on breast benign masses
Dongming CHU ; Bing GU ; Guoqiang RONG ; Xian LIU ; Ye WANG
China Oncology 2001;0(02):-
Background and purpose:Breast masses is woman's common diease,With the development of people's living.They are eager to find a new method which is efficient and less pain to replace conventional open surgery.So Mammotone appears.We assessed the efficacy of Mammotome biopsy system for the patients with single and multiple breast masses.We assessed the efficacy of Mammotome biopsy system for patients with single and multiple breast masses.Methods:From Janurary 2004 to April 2005,patients with single and multiple breast masses underwent Mammotome and conventional surgery respectively.Two methods has been compared from the aspects of difficulties,side effects,prognosis and degree of patient's satisfaction.Results:The length of excisions,anesthetic dosage,operational time,pain etc with Mammtome group were superior to the conventional group,especially for the patients with multiple breast masses.There were no difference in terms of bleeding during or after operation for two groups.Patients were followed up 3 to 15 months,none of the patients had relapse and patient's satisfaction was very encouraging.Conclusions:The color guided Mammotome showed very promising results for the patients with breast benign masses,and it was very useful for the masses either located deeply or were multiple.
10.The establishment of emergency preplan for workplace violence in emergency department
Ye SUN ; Guoqiang ZHANG ; Hua ZHANG ; Su FU
Chinese Journal of Emergency Medicine 2017;26(4):473-477
Objective To prevent the occurrence of violence in the emergency department,to reduce the damage to medical personnel,and to maintain the normal medical order in emergency department.Methods A retrospective analysis of medical incidents of violence in the emergency department has been made.A root cause analysis (RCA) group has been established to explore the root cause of the incident and to make the violence emergency preplan of emergency department.Results Medical personnel have been trained according to the plan.It has improved the awareness of health care workers.The incidence of violent injury incidents decreased.Conclusions The establishment and training of emergency preplan can improve the awareness and prevention ability of emergency medical staff to violence injury.The safety of medical staff in emergency department can be guaranteed.