1.Application of digital artery island flap for soft tissue defects of finger
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To investigate the effectiveness of repair of soft tissue defects of finger by using the digital artery island flap.Methods A total of 25 cases of soft tissue defects of finger were treated by using the digital artery island flap in this department from August 2003 to November 2004.The flap was 2.0~3.0 cm ? 1.5~3.0 cm in size.Results The flap had survived in all the 25 cases.The operation time was 60~90 min(mean,75 min),and the intraoperative blood loss was 25~40 ml(mean,32 ml).The skin graft necrosed by one-third of area in 2 cases,which was cured by a re-grafting.Follow-up observations in 23 cases for 6~18 months(mean,13.5 months) revealed the flaps with normal color,elasticity,and appearance.The static two-point discrimination was 6.5~8.8 mm(mean,7.5 mm).The digital pain and temperature sensation had recovered to normal,and the patients reported satisfactory sensory and motor functions.Conclusions Characterized by simple performance and satisfactory outcomes,digital artery island flap is an ideal choice for the coverage of soft tissue defects of finger.
2.Application of APACHE Ⅱ scoring system in severe cerebral hemorrhage
Clinical Medicine of China 2011;27(11):1167-1169
Objective To evaluatethe application value of APACHE Ⅱ on the prognoses in prediction of pin hole multi-directional intracranial hematoma aspiration to cure severe cerebral hemorrhage.Methods APACHE Ⅱ scoring system was conducted in randomly collected 58 severe cerebral hemorrhage patients' data (30 patients underwent surgical treatment,28 patients underwent conservative treatment)to evaluate the disease severity,prognosis and effect of the pin hole multi-directional intracranial hematoma aspiration.Results The APACHE Ⅱ score of treatment group on the first day was 28.00 ± 1.92 and the predicted mortality was 0.86 ±0.03.The score was decreased obviously on the tenth day(8.20 ± 0.76)and the predicted mortality was 0.57 ± 0.05.The actual mortality was 33.33%.Conclusion APACHE Ⅱ scoring system is suitable for judging the disease severity and predicting the prognosis of severe cerebral hemorrhage patients,it proves that surgical treatment effect of the pin hole multi-directional intracranial hematoma aspiration is remarkable.
3.Research on information support services of hospital research projects
Lili WANG ; Guoping YU ; Peiguo XU
Chinese Journal of Medical Science Research Management 2011;24(2):131-132
This paper analyzes the needs for and feasibilities of information support services at hospital libraries for scientific research.It also explores the major contents of hospital information support services,hoping to find a more reasonable information services model to meet the needs of the rapidlygrowing research projects.
4.Inhibition of Bcl-2 Antisense Oligonucleotide Combined with Radiation against Lung Carcinoma Cells
Wei HU ; Guoping SHAN ; Changhui YU
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To study the inhibitory effect of bcl-2 antisense oligonucleotide(ASODN)combined with radiation on lung carcinoma cells NCI-H446.[Method]The cultured NCI-H446 lung carcinoma cells were divided into 5 groups:control,pure radiation,nonsense+radiation,lipofectin+radiation,ASODN+radiation.Every group except for control were assayed by MTT on the inhibition rates,24h,48h,72h after 10Gy irradiation respectively.[Results]The inhibitions of lung carcinoma cells NCI-H446 were observed in ASODN+radiation,lipofectin+radiation,nonsense+radiation and pure radiation groups.The differences between the ASODN+radiation group and the other three groups were significant(P
5.Balloon catheter dilation of esophageal caustic ingestion stenosis in children
Juming YU ; Guoping FAN ; Weixin ZHONG
Journal of Interventional Radiology 2001;0(05):-
Objective To evaluate the methods and effect of balloon catheter dilation of esophageal caustic ingestion stenosis in children. Methods We analysed 18 cases, including 10 cases of esophageal stenosis due to ingestion of sulphuric acid, 7 cases of esophageal stenosis caused by ingestion of sodium carbonate and the last one through ingestion of chemical materials include zinc sulphate. Barium esophagogram was taken before dilation for every patient and the balloon size varied from 4 mm?40 mm to 16 mm?40 mm or 20 mm?40 mm in diameter was selected for the procedure. Results 18 cases were all successful in dilation by balloon catheter, without esophageal perforation and other complications. The satisfactory results maintained from six months to thirty months with remarkable improvement clinicoly. Conclusions Balloon catheter dilation is a simple, safe and reliable method for the treatment of esophageal caustic ingestion stenosis in children, and should be recommended as the first choice.
6.Balloon catheter dilation of benign esophageal stenosis in children.
Guoping FAN ; Juming YU ; Weixing ZHONG
Journal of Interventional Radiology 1994;0(03):-
Objective To evaluate the methods and effect of balloon catheter dilation of benign esophageal stenosis in children. Methods 9 cases had an anastomotic stenosis after surgical correction of esophageal atresia; 11 cases of esophageal stenosis due to ingestion of caustics; one case had an lower esophageal stenosis after Nissen surgery and one case after gastroesophagoplasty. Age ranged from 17 days to 7 years. Each case had a barium esophagram before balloon dilation. The balloon size varied from 3 to 10 mm in diameter. Results 21 cases were successful after dilation of balloon catheter. There were no esophageal perforation and complications. The satisfactory results maintained from six months to thirty months. Conclusions Balloon catheter dilation is a simple、safe and reliable method for the treatment of benign esophageal strictures in children as the first choice.
7.Determination of Dracorhodin and Curcumin in Dieda Pills by UPLC
Chunhui ZHANG ; Yu YU ; Guoping WANG ; Chao FU ; Youlan WANG
China Pharmacist 2016;19(6):1206-1208
Objective:To determine the content of dracorhodin and curcumin in Dieda pills by UPLC .Methods:A UPLC method was adopted.The determination was performed on a Waters Acquity UPLC BEH C 18 column(100 mm ×2.1 mm,1.7 μm) with the mobile phase consisting of acetonitrile-0.05 mol· L-1 NaH2PO4(50 ∶50).The detection wavelength was 440 nm for dracorhodin and 431 nm for curcumin, the column temperature was 30℃and the flow rate was 0.1 ml· min-1 .Results:There was a good linear range of 0.001 8-0.036 4 μg(r=0.999 9)for dracorhodin and 0.000 8-0.015 6 μg(r=0.999 9) for curcumin.The average recovery for dracorhodin was 97.94%(RSD=0.89%) and that for curcumin was 98.45%(RSD=0.91%).Conclusion:The method is simple, rapid and reproducible ,which can be used for the determination of dracorhodin and curcumin in Dieda pills .
8.Effect of herbal tongxinluo on thrombus formation and neointimal hyperplasia of the balloon injured rabbit peripheral arteries
Jun HUANG ; Chunjian LI ; Guoping YANG ; Meiling YU
Chinese Journal of Clinical Pharmacology and Therapeutics 2001;6(1):35-37
AimThe effect of herbal tongxinluo on the thrombus formation and neointimal hyperplasia of the balloon injured rabbit abdominal aorta and iliac artery was observed. Methods36 New zealand rabbits were divided randomly into 3 groups: tongxinluo group(16 rabbits); aspirin group(11 rabbits) and control group(9 rabbits). The rabbits were treated with herb tongxinluo 0.38g·kg-1 · d-1, aspirin 50mg·kg-1 · d -1 and 0.09% natrium chloride 10 ml · d-1 alternatively. The arterial injury model was made 1 week after taking the medicine and the injured segments were taken at 24 hours,1 week or 1 month after the procedure, then the samples were stained by hematoxylin and eosin. The thrombus formation and the neointimal hyperplasia of the injured arteries were observed under microscope. Results The arterial neointimal hyperplasia was seen in both abdominal aorta and iliac artery 24 hours and 7 days after the balloon injury in each group,which led to stenosis in 5%~40% of the arterial lumen, the neointimal hyperplasia was much more significant in 2 rabbits 1 month after the balloon injury. The ratio of the arteries with thrombosis in aspirin group was less than that in the other 2 groups, but the difference was not significant. The ratio of neointimal hyperplasia in tongxinluo group was significantly less than that in aspirin and control groups. Conclusion The balloon injured rabbit abdominal aorta and iliac artery appeare to be an ideal model in researching restenosis after percutaneous transluminar coronary angioplasty(PTCA) . Herbal Tongxinluo significantly inhibit the neointimal hyperplasia of the balloon injured rabbit peripheral arteries, which indicate that herbal Tongxinluo might be a promising medicine in preventing restenosis.
9.A case study of leukemia with irregular anti-Ce IgG antibody
Guoping ZHONG ; Wei SHI ; Kaimei LIAO ; Jingqin BI ; Yu SUN
Journal of Peking University(Health Sciences) 2004;0(02):-
When we did compatibility testing, we found a case of leukemia with irregular antibody. The antibody specificity was identified as anti-Ce using panel-cell, and was IgG antibody. The anti-Ce antibody had both anti-C and anti-e activity. It is very difficult to find a Ce antigen negative blood for transfusion. The compatible donors rate is very low, only 2%-3%.
10.Research of the theory model and realization path for social evaluation of public hospitals from the social governance perspective
Xiaohe WANG ; Yu QIAN ; Chengjian CAO ; Guoping WANG ; Kechun WANG
Chinese Journal of Hospital Administration 2016;32(10):744-747
Social evaluation governance strategy was introduced to study the social management path for public hospitals.On the basis of definition of social governance and social evaluation theory, clarification of the concepts and relationship logic of public hospital′s social evaluation,and analysis of the context analysis of their social evaluation policy,the paper discussed the establishment of social evaluation and governance theory logic framework of public hospitals.In terms of such realization paths as the purposes,indexes,entities,and methods of the evaluation,as well as result release and application of the evaluation,recommendations were made.