Objective To study the application of urine test reagent for cancer screen and monitoring URC significance.Methods Examined tumor patient urine separately and 80 on esophagus cancer,stomach cancer and cardiac cancer with URC.Results Esophagus cancer the postive rate is 78.9% .the stomach cancer the positive rate is 88.5% .the cardiac cancer the positive rate is 82.4% .Conclusion URC has certain specificity to malignant tumor's examination.is specially sensitive to digestive system's tumor.Its manipulation is simple and convenient.It is valuable for early dignosis and prognosis of malignant tumor.