1.Studies on Resource Utilization of Chinese Drug Dwarf Lilyturf (Ophiopogon japonicus)
Chinese Traditional and Herbal Drugs 1994;0(04):-
Maidong"(Radix Ophiopogonis), is a traditional Chinese drug. Chinese Pharmacopoeia (1990) recorded that the botanical origin of "Maidong" is Ophlopogon iaponicus(L.f.) kerGawl. (Liliaceae). A recent survey of drug resources in Zhejiang, Sichuan, Hubei, Hunan,Yunnan, Guizhou, jiangsu, Anhui and Fujian Provinces showed that Plants under the general name "Maidong" involve 26 species and varieties from Gen. Ophiopogon to Gen. Liriope.Among these, 16 species and varieties are used as "Maidong"in commerce, the most popular being O.japonicus, L.spicata var. Prolifera and L.muscari. The steroid saponins and homeisoflavonoids contained in the tuberous roots of 16 species and varieties mentioned above awere compared on the basis of HPTLC with 45 steroid saponins and 5 homeisoflavonoids as uthentic samples. The results showed that the plants belonging to Gen. Ophiopogon contain either steroid saponins composed of ruscogenin or diosgenin, or homeisoflavonoids; the plants belonging to Gen. Liriope contain only steroid saponins composed of 25(S)-ruscog-enin or yamogenin. It is easy to identify the varied species and varieties on TLC. The polysaccharide in the tuberous roots of the 16 species and vartieis was determined by visible spectrophotometry. Results indicated that the polysaccharide content in varied species is very different, and is also dependent on locations, cultivated years and the grade of crude drug.
2.Studies on the Traditional Chinese Medicine Shouwu Ⅱ.Botanical Origins and Applied Drugs
Jun LI ; Guojun XU ; Luoshan XU
Chinese Traditional and Herbal Drugs 1994;0(01):-
A survey on drug resources and identification or the commercial drugs showed that Heshouwu was derived from Polygonum multiflorum and the roots of another two species of the same family were misused as Heshouwu. The roots of 6 species of Cynanchum genus, Asclepiadaceae were used as Baishouwu in different regions. The index of botanical identification was listed. Botanical origins, distribution, production and sale of "Shouwu" were investigated.
3.Survey and Identification of Commercial Samples of Shihu (Dendrobium Sw.)(Ⅲ)
Guoxiang MA ; Guojun XU ; Luoshan XU
Chinese Traditional and Herbal Drugs 1994;0(07):-
A survey of the resources of Dendrobium Sw. and identification of commercially available samples showed that 22 speices of Dendrobium Sw., 1 species of Ephermerantha Hunt et Summerh. and 1 species of Pholidota Lindl. were processed as Chinese drug "Shihu" in Xishuangbanna, Yunnan. But the commercial drug came mainly from D. crystallinum Rchb.f., D. fimbriatum Hook., D. moschatum (Buch.-Ham. ) Sw. and D. chrysotoxum Lindl..
4.On State-of-art of Treatment of Very-early Stage Hepatocellular Carcinoma
Yun XU ; Qiang SHEN ; Guojun QIAN
Chinese Journal of Minimally Invasive Surgery 2015;(8):739-743
[Summary] In the treatment of very-early stage hepatocellular carcinoma ( HCC) , several therapies have their own strengths . Liver transplantation, surgical resection, and percutaneous ablation are the most effective procedures for very-early stage HCC.Liver transplantation is difficult to carry out due to lack of donors .Surgical resection and percutaneous ablation are the most commonly used methods with ideal effects .Compared with surgical resection , percutaneous ablation has its obvious advantages in patients with small HCC and senile patients , but the recurrence rate is relatively high .When the above mentioned three methods are not feasible , transarterial chemoembolization is a remedial treatment .Combined use of local therapy is superior to topical therapy alone and suitable for patients with unresectable lesions .Theobserving therapystill needs more clinical studies to confirm its safety and effectiveness .
5.Studies on the Chinese Drug Shasheng──Ⅴ.Comparison of Antitussive and Expectorant Activities
Fengfei TU ; Hongbin ZHANG ; Guojun XU
Chinese Traditional and Herbal Drugs 1994;0(01):-
Shasheng is a common Chinese drug used as antitussive and expectorant. A survey showed that the original plants of Shasheng on the current market consist of more than 30 species. To appraise the qualities of Saasheng scientifically, the antitussive .and expectorant activities of ten species of Shasheng were compared. Rosults showed that the EtOH extracts of the roots of Glehnta littoralis, Adenophora stricta subsp. henanica, A. potaninii and A .liliifolioides are very effective as autitussive,while those of A .liliijoliolioides,A.stricta subsp. sessilifolia and A. potaninii are very effective as expectorant.
6.Determination of Bis-(5-formyl-furfuryl)-ether and 2,4-Dihydroxy-6-methoxy-3-methyl-acetophenone in the Root of Yuexiandaji(Euphorbia ebracteolata) by HPLC
Kuijun ZHAO ; Guojun XU ; Rongluan JIN
Chinese Traditional and Herbal Drugs 1994;0(02):-
An HPLC method for the quantitative analysis of bis (5-formyl-furfuryl ) -ether an d 2, 4-dihydroxy-6- methoxy-3-methyl- acetophenone in Chinese drug,Langduc (Euphorbia ebracteolata)was developed. The solvent system used was methanol-water-10% acid (45 : 55 : 2 ) (adjusted to pH 5.4 by 10% ammonia ) on ODS columm at 289nm.Tetrahydro palmatine was used as an internal standard. The operation can be completed in 30min.This method is sensitive,simple and accurate with good reproducibility.It can be applied to the quality control of the crude drug of E. ebracteolata.
7.The Treatment in Phlebothrombosis of Leg by UK Infusion through Dorsal Veins of Ipsilateral Foot.
Guojun LI ; Maoheng ZU ; Hao XU
Journal of Interventional Radiology 1994;0(03):-
Purpose: Introduce the way of the treatment of deep veinous thrombosis of leg. Meerials and Methods: 26 patients (27 legs) refred for phlebothrombosis of leg, were prove by lower limb Phlebography or ECT. 100~200 thousand unit UK was infused through dorsal veins of sick leg, once or twice per day with 7 days a coure of treatment. Results: 17of 27 legs with phlebothromb0sis, were cured the successful rate 63%, 8 were improved, 30%; 2 were noneffective, 7%. No bleeding occurred 1 case of pulmonary segment embolism. Conclusion The way of the treatment of lower limb deep vein thrombosis by infusion of UK from dorsal veins of sick foot is safe and reliable.
9.Efficacy analysis of percutaneous microwave ablation for patients with unresectable early stage hepatocel-lular carcinoma
Neng WANG ; Qiang SHEN ; Yun XU ; Guojun QIAN
The Journal of Practical Medicine 2016;32(13):2164-2167
Objective To investigate the efficiency and prognostic factors for the patients with hepatocel-lular carcinoma (HCC) at unresectable early stage when treated with percutaneous microwave ablation. Methods From January 2007 to January 2010 , 105 cases of at unresectable early stage were treated with percutaneous microwave ablation. Complete response rate, major complication rate, overall survival rates, disease-free survival rate were observed and prognostic risk factors were analyzed. Results The complete response rate was 95.7%. The major complication ratewas 3.8%. The 1-, 3-, and 5-year overall survival rates were 97.1%, 66.7%, 46.7%, and the corresponding disease-free survival rates were 82.9%, 48.6%, 31.4%, respectively. Age > 65 year and tumor size > 3 cm were independent risks for disease-free survival. Age > 65 year and recurrence were independent risks for overall survival. Conclusions Percutaneous microwave ablation is a safe and efficient ther-apy for HCC at unresectable early stage.
10.Study of the Influencing Factors of Myocardial Infarction Patients Care Burden of Caregivers
Guojun XU ; Tao CONG ; Dong CHANG ; Yan ZHANG
Journal of China Medical University 2015;(7):622-625
Objective Through the evaluation of acute myocardial infarction patients care burden of caregivers,to understand caregiver stress con?dition,and to investigate the effective predictors of acute myocardial infarction patients care burden of caregivers,so as to provide the basis for im?provement of the care burden. Methods A cross?sectional study was conducted through convenience sampling using Zarit Caregiver Burden Inter?view as the measuring tool. Questionnaires were collected by face?to?face structured interviews towards caregivers. Care burden of caregivers was eval?uated on these primary caregivers of patients with acute myocardial infarction. Results Caregivers of patients with myocardial infarction endure high care burden level. There were statistically significance among patients with different ages or revenue,the relationship of caregivers with patients,nurs?ing hours per day,psychological alignment and patients′self?care ability. Conclusion Caregivers of patients with myocardial infarction endure high care burden level. The relationship between caregivers and patients,the patient′s gender,nursing total time,nursing time every day,and the pa?tient's life self?care ability are contributed to be predictive factors. Future interventions should be strengthen on the psychological ability of the align?ment as well as measures to improve the self?care ability of the patient's life.