The main function of the pre-preparing water and disinfecting set-up for artificial kidney is to tackle problems,such as poor water quality and more impurities (when hemodialysis is done) which would affect the hemodialzing effects,regeneration of the hemodialyzer and reduce the life of the artificial kidney.The whole set-up is composed of two parts:(1)the pre-preparing water system,i,e.the dual filter which can produce Premium-guality water which the particle under 5?;(2)washing & disinfecting device which can protect the hemodialyzer from clogging and avoid the effects resulting from the clogging.Clinic practice shows that this device is reliable,easy to operate.

Bronchiolitis is a common lower respiratory infection disease in children younger than two years old.The main pathogen of bronchiolitis is respiratory syncytial virus,which is also associated with the asthma.By now,it is still unknown about the pathogenesis of bronchiolitis.Recent findings provide that T helper17(Th17) cells play an important role in bronchiolitis.This review summarizes the progresses of regulation of Th17 cells development,Th17 cells function,and the relationship between Th17 cells and bronchiolitis.

Objective To explore the application of SCPC in the apexification.Methods 153 teeth with incompletely developed root were treated with SCPC in the apexification.All of the teeth were followed up for 0.55years.Results 85% of the treated teeth got the good clinical effects of root development and apical closure.Conclusion SCPC is an ideal material to use in the apexification.

Objective To understand the paroxysm spreads characteristic, among Shenzhen community, and to offer some reference about preventing STD. Methods analyze STD in Pingshan community of Shenzhen according to the data in the disease reports from 2005 to 2007 by descriptive Epidemiology method. Results In the disease re-port of Pingshan community in Shenzhen City,there are 160 cases of t6he STD in 2005. 182 cases in 2006. 145 cases in 2007. Incidence rate is 1.683‰, 1.225‰, 1.710‰. Total incidence rate is 1.522%‰, male incidence rate is 1.082‰,female incidence rote is 0.441‰; Among 6 kinds STD, the ratio of gonorrhea is highest, occupying 28.13%. Different sex has different ratio. The male gonorrhea ratio is highest,occupying 34.97%, but the female syphilis is highest,occupying 48.94% ;6 kinds of sexual infectant diseases root in having sex without marrying and it accupied. 69.83%. The origin of disease has difference in sex. Conclusions The incidence of a disease of sexual infectant is a bit high. The main way of transmit is sex osculation without marrying and the inborn syphilis The HIV of pregant woman is not very well,promoting to increase the drumbeating work of sex healthy education,giving publicity to keep your self-esteem gereatly Lets use as many condoms as possible in that sination. The Physical examination of sexual infectant diseases for the pregant women should be strengthended.

OBJECTIVE: To discuss the responsibility transformation of pharmacists and its necessity.METHODS: The process of transformation in fundamental responsibility of pharmacists were reviewed; the current situation in the development of pharmacist group was presented, and the necessity to transform the responsibility of pharmacists was analyzed.RESULTS&CONCLUSION: It is the contemporary demand to transform the responsibility of pharmacists in China.Training of pharmacy talents and the development in the field of pharmacy, construction of information system, the development and utilization of information, scientific research, the development and utilization of new technology and method, as well as the strengthened management of drug distribution chain, and the establishment of Pharmacist Law can all help to achieve a full range of pharmaceutical care.

BACKGROUND: Fetal microchimerism is a kind of stem cells which comes from fetus in pluripara. The research on fetal microchimerism is a hotspot because it may affect the health condition of pluripara.OBJECTIVE: To introduce the methods of how to detect fetal microchimerism, and the function of fetal microchimerism during disease and tissue repair of the mother.METHODS: Fetal microchimerism was used as a key word, and papers published before 2011-05-20 were retrieved in PubMed. Repetitive papers were eliminated.RESULTS AND CONCLUSION: Totally 655 papers were retrieved, and finally 26 were reviewed. There are several methods used for fetal microchimerism detecting, and fetal microchimerism may pay an important role in the pathomechanism of pluripara autoimmune diseases, cancer and tissue repair.

The influences of propylene glycol mannate sulfate (PGMS) on experimental thrombosis and thrombolysis in vivo were studies after iv 8. 125, 6. 25, 12. 5 , 25mg/Kg in rabbits, and the effect of antithrombosis of PGMS was compared with that of heparin. The results showed that PGMS possessed remarkable effect of antithrombosis. In order to explore the mechanism of antithrombosis of PGMS, we studied the influences on the fibrinolytic and coagulant function of rabbits. The results showed that PGMS can pronouncedly prolong the prothrombin time (PT), thrombin time (TT), kaolin partial thromboplastin time (KPTT), and enhance the activity of antithrombin-III (AT -III). PGMS can cause a remarkable increase in fibrin degradation product (FDP) , shorten euglobulin lysis time (ELT) , and a decrease in the contents of fibrinogen and plasminogen activity. These results suggested that PGMS probably exert the antithrombotic effect by inhibiting coagulation and activating fibrinolysis.

AIM: To investigate the effect of pyrrolidine dithiocarbamate (PDTC), a specific inhibitor of NF-κB on the proliferation and apoptosis of K562 cells and to explore the anti-tumor mechanism of PDTC.METHODS: Trans AM~(TM) NF-κB p65 kit was used to detect the activity of p65 in K562 cells treated by PDTC. The effect of PDTC on the proliferation of K562 cells was measured by WST-1 method. DNA damage was detected by single cell gel electrophoresis (comet assay). The procaspase-3 and activated protein level of caspase-3 were detected by Western blotting.RESULTS: The activity of p65 in K562 cells was inhibited after treated by PDTC (P<0.01). Simultaneously the cell proliferation was significantly inhibited in a dose-and time-dependent manner (P<0.01). The degree of DNA damage in K562 cells treated with PDTC at concentrations of 25 μmol/L, 50 μmol/L or 100 μmol/L was more severe than that in control. The rates of comet cells in the PDTC-treated groups (43.50%, 84.00%, 95.63%) were significantly higher than those in control (9.75%, P<0.01), and it was also dose-dependent. The expression of procaspase-3 and activated caspase-3 protein were detected in the cytoplasm of the K562 cells treated by PDTC by Western blotting.CONCLUSION: NF-κB plays an important role in regulating cell proliferation and apoptosis in K562 cells. PDTC inhibits NF-κB activity and elevates the expression of caspase-3, which is related to increase in cell apoptosis.

Objective To observe the influence of metabolic syndrome(MS)on the left ventricular hypertrophy(LVH)in the essential hypertension(EH)patients.Methods 76 EH patients in middle to advanced ages were selected.Clinical examinations including blood pressure,serum lipid,plasma glucose and body mass index(BMI)were performed.The patients were divided into EH group and essential hypertension with HMS group.The left ventricular posterior wall thickness(LVPW),the left ventricular end diastolic dimension(LVDd),and interventricular septal thickness(IVS)were detected.The left ventricular mass index(LVMI)was calculated after Doppler and 30 controls were observed.Results LVPW,IVS,LVDd,LVMI and the rate of LVH were obviously higher in EH patients than that in the controlS(P＜0.05),and these were also higher in HMS than that in the controls and the EH patients(P＜0.01).Conclusions The degree of the left ventricular hypertrophy in EH patients with metabolic syndrome is more severe than that in EH patients.