1.Research of PACS Based on DICOM and Distributed Objects
Jianlin YE ; Zhaolin ZHANG ; Guohua WU
Journal of Practical Radiology 2000;0(12):-
Objective To change the two-tiered C/S architecture of traditional PACS.Methods Based on the deeply research of PACS architecture,combination with DICOM and distributed object technology,propose distributed PACS system architecture,the three-tire client/server framework of distributed object technology introduced into the architecture of PACS to design the new architecture.Results In comparison with traditional PACS that were based on DICOM networks,the distributed PACS were improved themselves in system architecture and performance,and PACS were more open and interoperable.Conclusion The new architecture not only enhances the performance of PACS,but also meets the need of open and high interconnectivity and interoperability.
2.Evaluation of the hematuria examination by urinary analyzer in forensic medicine practice
Guohua CHEN ; Li CHEN ; Hanying YE
Chinese Journal of Forensic Medicine 1987;0(03):-
The role of the hematuria examination by urinary analyzer in forensic medicine practice was evaluated in the present study.By using the chemical analysis of urinary analyzer and urinary sediment microscopy,the erythrocytes in 418 urine samples were examined simultaneously.The results showed that the negative outcome was found in 276 cases,+ in 58,++ in 35,≥++ in 84 by urinary analyzer,while negative outcome in 274 cases, +- and + in 31, ++ in 1 ,≥++ in 37 with consistent rates of 99 26%, 53 45%, 2 86% and 44 05% respectively.There was high significant difference between the positive and negative outcome and between the trauma mild (≥++) and slight trauma outcome (≤+) as determined by these two methods ( P
4.The clinical value of PCT levels in bacteria identification in ICU patients with bloodstream infection
Jian WANG ; Guohua ZHUANG ; Ye NIU ; Hong LI ; Jianping XIA
Journal of Chinese Physician 2015;17(9):1369-1371,1375
Objective To investigate the clinical value of procalcitonin (PCT) levels in bacteria identification in intensive care unit (ICU) patients with bloodstream infection.Methods There were 540 cases of patients with bloodstream infection in our ICU between December 2007 and December 2013.The PCT levels and bacteria were identified.The application effectiveness of PCT levels in the bacteria identification was studied.Results The G+ bacteria infection rate was 49.63% (268/540),G-bacteria infection rate was 38.52% (208/540),and the fungal infection rate was 11.85% (64/540).The patients of G-bacteria had significant difference with G + bacteria and fungal infection (P < 0.05).The PCT average and positive rate of G-bacteria were significantly higher than G + bacteria and fungi group (P < 0.05),respectively.G+ bacteria and fungi infection did not have significant difference (P > 0.05).When PCT > 2.04 ng/ml,the sensitivity and specificity that applying serum PCT level to identify the between G-and G+ bacteria were 82.18% and 76.09%,respectively.When PCT >3.16 ng/ml,the sensitivity and specificity that applying serum PCT level to identify the between G-and fungus bacteria were 59.42% and 65.73%,respectively.Conclusions The identification between G-bacteria and G + bacteria,fungi with applying PCT level in bloodstream infections had high accuracy.When the PCT levels was greater than 2.04 ng/ml,the occurrence of G-bacteria was greater risk of infection.The accuracy of PCT level identifying the G + bacteria and fungi was poor.
5.P53 up-regulated modulator of apoptosis in gastric carcinoma
Guohua HU ; Shan WANG ; Yingjiang YE ; Kewei JIANG ; Xun HUANG
Chinese Journal of General Surgery 2008;23(11):859-862
Objective To investigate the expression of p53 up-regulated modulator of apoptosis (PUMA) and p53 protein and relationship with clinicopatbological parameters in human gastric cancers. Methods Primary gastric carcinoma and adjacent normal mucosa were obtained from 84 consecutively enrolled patients undergoing gastric cancer resection at Peking University People's Hospital during the period from April 2001 to May 2003. Immunohistochemistry staining was used to measure the expression of PUMA and p53 proteins both in normal and malignant tissues. Results PUMA expression is significantly weaker in primary gastric carcinoma compared to adjacent normal mucosa (P <0. 01 ). Weak PUMA expression in gastric cancer correlates with depth of tumor invasion ( P < 0. 01 ), advanced pTNM stage ( P < 0. 05 ) and poor overall survival of patients ( P < 0. 05 ). p53 protein expression in gastric carcinoma is significantly higher than adjacent normal mucosa ( P < 0. 01 ). There was a significant negative correlation between the expression of PUMA protein and p53 protein in gastric carcinoma (P < 0. 05 ). Conclusion PUMA expression in gastric carcinoma is significantly lower compared to adjacent normal mucosa. Weak PUMA expression in gastric cancer correlates with depth of tumor invasion, later pTNM stage and poor overall patient survival.
6.Effect of Herba Cichorii Extracts in Reducing Serum Uric Acid and Blood Lipid
Yi SA ; Bing ZHANG ; Xiaoqing LIU ; Guohua YE
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(04):-
s:Objective To study the effect of Cichorii Extract(CE)N2 on quail with hyperuricemia and hypertriglyceridemia.Methods Quail models were established by feeding of yeast.Effect of CE N2 on biochemical parameters such as serum uric acid,triglyceride,nitric oxide(NO),xanthine oxidase(XOD),etc.were observed dynamically.Results As compared with the control group,CE N2 in three different dosages decreased serum uric acid,triglyceride and NO;CE N2 in high and low dosage could also lower the serum activity of XOD.Conclusion CE N2 can lower serum uric acid and triglycercide levels in quails with hyperuricemia and hypertriglyceridemia.
7.Research progress of functional magnetic resonance imaging in radiation-induced brain injury after head and neck carcinoma radiotherapy
Junchen LI ; Guohua LI ; Ye TIAN ; Chunhong HU
Chinese Journal of Radiation Oncology 2017;26(1):98-102
Radiation?induced brain injury is a common adverse reaction to radiotherapy for head and neck carcinoma, and may develop into radiation?induced brain necrosis in some patients. The disease has a substantial impact on the quality of life and 5?year survival in patients. Early diagnosis and prevention are important for the clinical treatment of radiation?induced brain injury. On the other hand, recurrence and pseudoprogression as complications of malignant tumor radiotherapy are also key problems for clinical diagnosis and identification of radiation?induced brain injury. Magnetic resonance imaging ( MRI) , especially functional MRI, provides an important approach for basic and clinical studies of radiation?induced brain injury.
8.TLC Qualitative Studies of 11 Species of Selaginella Medicinal Material
Guohua CUI ; Ying SHI ; Bin GAO ; Fang YE ; Kexiang ZHOU ;
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To establish an effective qualitative discrimination method for Selaginella medicinal materials.Meth- ods Thin layer chromatography(TLC)method was used.Results The TLC method has a good specialization for identifying Selaginella medicinal materials and can distinguish Selaginella rnoellendorfii from other 10 familiar species in northern areas of Guangdong province.Conclusion The method can help to control the quality of Selaginella moellendorfii Tablet.
9.Development of Non-Contact Monitoring Device for Breathing and Heartbeat.
Ye HU ; Chuantao LI ; Fugui QI ; Shuaijie WANG ; Hua ZHANG ; Jianqi WANG ; Guohua LU
Chinese Journal of Medical Instrumentation 2015;39(4):244-248
Physiological monitoring devices in modern clinical area are basically used electrodes or sensors directly touching the surface of human subject body, which will increase physiological and psychological load of the subjects. In order to realize non-contact monitoring of respiration and heartbeat, firstly, the micro bioradar was used to detect human body motion signal. Then, the respiration signal and heartbeat signal was extracted from the body-motion signal by using signal and conditioning circuits, digital filter and signal processing. Finally, the results of heart rate and breathing rate was wirelessly transmitted. The experimental results showed that the device for non-contact monitoring of respiration and heartbeat waveforms has advantages of small volume, low power consumption, which can realize the monitoring of physiological parameters in real time.
Heart Rate
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Humans
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Monitoring, Physiologic
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instrumentation
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Respiration
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Signal Processing, Computer-Assisted
10.Posterior short-segment pedicle screw fixation at the injured level for thoracolumbar spine fractures
Yunrong ZHU ; Xiaojian YE ; Jiangmin YU ; Yuquan JIANG ; Huixue WANG ; Chunquan FAN ; Hailong HE ; Guohua XU
Chinese Journal of Trauma 2010;26(3):221-224
Objective To discuss indications,operation method and clinical outcome of posterior short-segment pedicle fixation at the injured level for treatment of thoracolumbar spine fractures.Methods A total of 38 patients with thoracolumbar spine fractures were equally randomized to Group A(treated with classic short-segment pedicle screw fixation)and Group B(treated with short-segment pedicle screw fixation at the injured level)based on fixation methods(19 patients per group).Preoperative and postoperative JOA score,segmental lordosis(Cobb' s angle),R value(anterior fractured vertebral body height/mean normal vertebral body height×100%),VSA score and internal fixation condition were assessed and compared clinically.Results All patients were followed up for 6-37 months(mean 20.5 months),which showed no statistical difference upon Frankel scores of two operation modes,while the segmental lordosis,VAS score and R value in Group B were than those in Group A.There occurred nuts loosening in one patient and screw bending in one in Group A.There was no implant breakage,loosening or emersion in Group B.Conclusion Posterior short-segmental fixation at the injured level is an adequate and effective procedure for compression fractures and mild to moderate burst fractures of the thoracolumbar spine.