1.INVESTIGATION OF KNOWLEDGE AND BEHAVIORS ABOUT CARDIOVASCULAR AND CEREBROVASCULAR DISEASES PREVENTION AND CONTROL AMONG COMMUNITY RESIDENTS IN GUANGDONG PROVINCE
Modern Hospital 2009;9(8):148-150
Objective To understand the situation of prevention and control knowledge and the relevant behaviors about cardiovascular and cerebrovascular disease among community residents in Guangdong Province in order to provide a basis for develop cardiovascular and cerebrovascular disease prevention and control work in the future.Methods Through a randomized sampling method chose community residents participating in cardiovascular and cerebrovascular diseases prevention and control among community residents in Guangdong Province consultation in Guangdong Province seven cities using questionnaire investigation.Results Total 1577 community residents were investigated, of which 50.4% were male, 49.6% female;the cardiovascular and cerebrovascular disease prevention and control knowledge different among the population with different gender, age and region, with statistic significance;according to investigation, 17.1%, 13.5% and 14.9% of the population investigated had the habit of smoking, drinking, and salty badly respectively;50.7% of population had health protection through dietary conditioning, which was 35.4% through the physical training.Conclusion Knowledge awareness situation of cardiovascular and cerebrovascular diseases prevention and control was poor among community residents in Guangdong Province, and risk factors of cardiovascular and cerebrovascular disease existed in the population;health education of cardiovascular and cerebrovascular diseases should be strengthened to change adverse behavior of community residents, develop a healthy and scientific way of life, prevent and control the disease.
2.Effect of Electroacupuncture on Motilin and Somatostatin inRats with Diabetes Gastroparesis
Xiuhong LI ; Guohua LIN ; Zhuocheng ZOU
Shanghai Journal of Acupuncture and Moxibustion 2015;(9):892-895
Objective To investigate the effect of electroacupuncture on motilin (MOT) and somatostatin (SS) in rats with diabetes gastroparesis (DGP). Methods One hundred clean healthy SD rats with negative urine glucose were chosen. After they were fed for three days and into a stable state, 30 rats were randomly selected as a control group. The other 70 rats were used as an animal model of insulin-dependent diabetes made with streptozotocin. At 10 weeks after model making, rats as successful models were randomly allocated to model and treatment groups, 30 rats each. The model group received no treatment and the treatment group, electroacupuncture at points Zusanli, Zhongwan and Weishu. Serum and antral MOT and SS were measured in every group before and after treatment. Results There were statistically significant differences in body weight and gastrointestinal propulsion rate between the treatment or model group of rats and the control group (P<0.01), and between the treatment and model groups after treatment (P<0.01). There was a statistically significant difference in blood glucose value between the treatment or model group of rats and the control group after model making and at 10 weeks and the end of treatment (P<0.01). There was a statistically significant difference in blood glucose value between at the end and 10 weeks of treatment in the treatment group (P<0.01). There were statistically significant differences in serum and antral MOT and SS contents between the treatment or model group and the control group (P<0.01), and between the treatment and model groups after treatment (P<0.01). Conclusions Electrocupuncture can markedly increase serum SS and antral MOT and decrease serum MOT and antral SS to ameliorate high blood motilin and somatostatin in DGP rats.
3.Diagnosis And Treatment For Sporadic Type of Painless Thyroiditis in Hyperthyroidism
Aimin DENG ; Yande LIN ; Guohua WANG
Journal of Chinese Physician 2001;0(06):-
Objective To investigate the incidence of sporadic type of painless thyroiditis (SPT),to analyse its laboratory characteristics, and explore the influence of different treatments on prognosis. Methods 43 patients with SPT, who differentiated from 276 patients with typical thyrotoxicosis, were randomly divided into treatment group (n=22) and control group(n=21).Results the incidence of SPT was 15 58%,the laboratory examinations in SPT differed from those of Graves disease, Plummer's disease and Hoshimotos disease. In treatment group the thyrotoxicosis continued(37 23?4 28) days, the euthyroidism continued(16.43?3.42) days and hypothyroxinemia continued(18.65?6.31)days,only one patients(4.54%) showed that repeated episode and had not left lifelong hypothyroidism; In control group the thyrotoxicosis continued(68 35?8 32) days, the euthyroxinemia continued(31 45?7 23) days and the hypothyroxinemia continued(102 42?21 34) days, 3 patients(14 28%)showed that repeated episodes and two patients(9 52%) left lifelong hypothyroidism in following 1 5 years;Conclusions SPT has less incidence than Grave's disease and more incidence than plummer's disease or Hoshimoto's disease in thyrotoxicosis. The laboratory examination could differentiate each other .The therapy of SPT could control thyrotoxicosis quickly,reduce recurrence rate and lifelong hypothyroidism.
4.Study on the Relationship Between Plasma Glucose Level and Insulin Secretion in Type 2 Diabetes
Aimin DENG ; Yande LIN ; Guohua WANG
Journal of Chinese Physician 2002;0(S1):-
Objective To study on the of insulin secretion relations to plasma glucose and the effect of different plasma glucose levels on insulin secretion stimulated by glucose.Methods 98 patients with type 2 diabetes were undergone 75g orally glucose tolerance test(OGTT) and insulin releasing test(IRT) 48hours after stopping administration of oral hypoglycemia agent.The data of plasma levels of glucose and insulin,and the time of peak glucose and insulin and postprandial plasma gluocse and insulin ,the time of peak glucose value,the ratio of maximal glucose to base glucose on base and stimulated insulin secrtion were analyzed statistically.Results The findings demonstrated that plasma glucose of OGTT has relation to base insulin level wihle no significance ,but to stimulate insulin (I max ) of IRT and the ratio of maximal insulin to base insulin(M/B 1).I max and M/B 1 when base glucose level excess 11 1mmol/L were one third of the same index when base glucose level less than 11 1mmol/L(P
5.MORPHOLOGICAL OBSERVATION ON ELASTIC FIBERS IN THE REMODELING MYOCARDIUM OF RATS AFTER INFARCTION
Hongping YIN ; Youfa ZHU ; Guohua LIN
Acta Anatomica Sinica 1957;0(04):-
Objective To investigate the changes and role of elastic fibers during the progression of ventricular remodeling after myocardial infarction(MI) in rats. Methods Male Sprague Dawley rats were induced by ligating the anterior descending coronary artery and were divided into the 2nd,4th,8th,12th and 21st week groups.Elastic fibers were evaluated in the infarct region using Masson trichrome staining,Uana orcein staining and image analysis.The expressions of TNF? and IL-1? were also detected by immunohistochemistry. Results Elastic fibers could be found within the infarct region in the 2nd week after MI,increased with time and reached the peak during the 8th to 12th weeks,decreased or were absent in the 21st week.The expressions of TNF-? and IL-1? were also detected in the infarct zone and increased with time.Conclusion Elastic fibers were involved in infarct healing and may play an important role in promoting ventricular remodeling.
6.Therapeutic Effect of Focus-Locating Scalp Circum-Needling for Ischemic Stroke
Yanhui LI ; Lping LI ; Guohua LIN
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
【Objective】 To observe the therapeutic effect of focus-locating scalp circum-needling for ischemic stroke (IS) at acute stage. 【Methods】 Sixty-one cases of IS were randomized to two groups: group A (n=31) was treated with acupuncture on homolateral scalp region projected by CT-located focus; group B (n = 30) was treated with acupuncture on conventional scalp regions which were in charge of motor and sensory function. The cases were treated with acupuncture once a day for 30 days. The changes of symptoms and signs and the plasma contents of norepinephrine (NE) and epinephrine (E) were observed before and after treatment. 【Results】 Twenty cases were cured, 10 markedly effective, 1 effective and 0 ineffective in group A; 11 cases were cured, 15 markedly effective, 4 effective and 0 ineffective in group B. The therapeutic effect in group A was better than that in group B (P
7.Study on the relationship of platelets activation and inflammatory reaction in hematoma at acute phase of intracerebral hemorrhage
Guohua ZHANG ; Jie LIN ; Caixiao CHEN
Journal of Clinical Neurology 1995;0(04):-
Objective To investigate the leukocyte infiltration inside the hematoma and the correlation between this and the expression of platelet P-selectin (CD62p) and platelet thrombin-sensitive protein (TSP) of patients with cerebral hemorrhage. Methods In 33 patients with cerebral hemorrhage treated with minimally invasive surgery, the expressions of platelet CD62p and TSP were detected by flow cytometry (FCM) and leukocyte counts were measured in intracerebral hematoma fluid and venous blood. The correlation analysis was performed between the two variables.Results The expressions of platelet CD62p and TSP in hematoma fluid were higher in patients with acute cerebral hemorrhage (20.25?1.82, 37.04?3.63) than those in venous blood (7.72?2.19, 12.32?2.81)(all P
8.Clinical significance of platelets activation in patients with acute cerebral hemorrhage
Jie LIN ; Guohua ZHANG ; Fuping SHI
Journal of Clinical Neurology 2001;0(05):-
Objective To study the platelets activation in patients with acute cerebral hemorrhage and its significance in perihematoma edema.Methods 33 patients with cerebral hemorrhage were treated with minimally invasive surgery.The volume of edema perihematoma was determined by CT technique before operation.The expressions of platelets CD62p and TSP in intracerebral hematoma fluid and venous blood were detected by flow cytometry(FCM).The correlation between the two variables was also analyzed.Results The expressions of platelets CD62p and TSP were higher in patients with acute cerebral hemorrhage than those in healthy individuals,and the expressions of platelets CD62p and TSP in intracerebral hematoma fluid were higher than those in venous blood.There were significant positive correlations between the expression levels of CD62p and TSP from the surface of platelets in hematoma and the edema size perihematoma(CD62p:r=0.4781,TSP:r=0.5183,all P
9.Effect of Heated Needle on the Pathological Changes of Articular Cartilage in Mice with Experimental Knee Osteoarthritis
Guohua LIN ; Wanyao LI ; Guolong SU
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
[Objective] To observe the effect of heated needle on the pathological changes of articular cartilage in mice with experimental knee osteoarthritis (OA). [ Methods ] Sixty-four NIH mice were randomly divided into 4 groups: heated needle group, electro-acupuncture (EA) group, model group and normal control group, 16 mice in each group. The mice models with knee OA were made with Xie's method, and then were treated for 2 weeks according to the experimental design. [Results] After treatment, the movable angle of right back knee in mice was increased in heated needle group and EA group ( P