1.Comparison of levobupivacaine and bupivacaine in spinal anesthesia during transurethral resection of prostate for elderly patients
Jian LI ; Guoguang JIN ; Weidong YE
Chinese Journal of General Practitioners 2011;10(7):501-503
Eighty elderly patients undergoing elective resection for the prostate were randomly divided into two groups, the levobupivacaine (observe group) and bupivacaine (control group) were used for spinal anesthesia, respectively. The level of sensory block and maintain time were T7±4 and (224 ±28) min in observed group, those in control group were T6±3 and (227 ±30) min, respectively ( both P> 0. 05). The mean arterial blood pressure of control group was (71 ±8) -(72 ±8) mm Hg (1 mm Hg = 0. 133 kPa) from 5 to 30 min after injection; meanwhile that of observed group was(75 ± 9) mm Hg (P < 0. 05). The incidences of hypotension and nausea were 10% (4/40) and 0% (0/40) respectively in observe group, and those were 30% (12/40) and 15% (6/40) respectively in control group (both P<0.05). The results indicate that levobupivacaine and bupivacaine have similar anesthetic effects, but levobupivacaine has fewer side effects and is more suitable for elderly patients.
2.Influence of Gastroesophageal Reflux Disease Morbidity Rate by High Salt Diet in Mare Island Area
Wuheng TANG ; Hai JIN ; Songcai LI ; Chunyu CAO ; Guoguang CHEN
Journal of Medical Research 2006;0(11):-
12,9.41%(148/1578);RDQ≤12,91.58%(1430/1578).Logistic multiple regression analysis of gastroesophageal reflux correlation factor studied:OR= 2.781.Conclusions The results showed:there were close correlation of high salt diet and GERED.
3. Establishment of a predictive model for outcomes in patients with severe acute pancreatitis by nucleated red blood cells combined with Ranson score and APACHE Ⅱ score
Jing WANG ; Xiaxia JIN ; Guoguang LU ; Yuan YUAN ; Bo SHEN
Chinese Journal of Laboratory Medicine 2020;43(1):63-70
Objective:
To explore a predictive model for outcomes of severe acute pancreatitis (SAP) patients.
Methods:
A retrospective study was conducted of 102 SAP patients from January 1,2016 to April 30,2018 from Taizhou Hospital in this study. The participants were divided into survival group and death group according to the outcome of 90 days after admission,88 cases were in survival group including 57 males and 31 females, aged 55.5 (40.3-69.8) years; 14 cases were in death group including 5 males and 9 females, aged 63.0 (50.8-80.8) years. Clinical data and laboratory indicators were compared between the two groups. Statistical analyses were performed to compare categorical variables. Chi-square automatic interaction detector (CHAID) was used to construct the prediction model of SAP patients′ outcomes. The study cohort consisted of SAP patients from August 1st 2018 to July 1st 2019 were collected to validate the prediction model.
Results:
(1)Statistical analyses were performed by chi square test and Mann-Whitney