1.Application of Mental Matching Strategy in the Teaching of Nursing Ethics
Chinese Medical Ethics 1996;0(01):-
Mental matching is a strategy of teaching materials transacting in emotional latitude of teaching psychology. Used properly, psychology matching strategy can improve the unification between teaching materials and students' need to adjust to the students' learning interests. This paper introduces the connotations and functions of mental matching strategy, and two types of mental matching strategies in the nursing ethics teaching are analyzed.
2.Effect of miR-210 on angiogenesis of renal clear cell carcinoma
Guodong ZHU ; Long YANG ; Ye TIAN
Basic & Clinical Medicine 2017;37(2):197-201
Objective To investigate the effect of miR-210 on angiogenesis of human renal clear cell carcinoma . Methods Detect the expression of miR-210 in 40 cases of renal clear cell carcinoma tissues , and analyze the rela-tionship between the expression of miR-210 and microvessel density ( MVD) .miR-210-ASO was lipotransfected in-to renal clear cell carcinoma cell line 786-O.RT-qPCR was used to verify the transfection effect .The effect of the supernatant of control group , negative control group and miR-210-ASO group tumor cells on the lumen formation of human umbilical vein endothelial cells ( HUVEC) was observed in a 3-D culturesystems .The transplantation tumor model of nude mice was established , and the effect of miR-210 on the formation of the transplanted tumor micro vessel was observed by endomucin and VEGF immunofluorescence staining under laser scanning confocal micro -scope.Results The expression of miR-210 was positively correlated with microvessel density in renal clear cell carcinoma ( P<0.05 ) .The expression of miR-210 was significantly decreased in 786-O cells transfected with miR-210-ASO( P<0.05 ) .The lumen formation of HUVEC cells co cultured with miR-210-ASO group cell supernatant was significantly less than that of control group and negative control group ( P<0.05 ) .The tumor volume of miR-210-ASO group was less than that of the control group , and the number of the micro vessel and the VEGF expres-sion were significantly less than that of the control group ( P<0.05 ) .Conclusions Inhibition of miR-210 can suppress blood vessel formation in renal clear cell carcinoma .
3.Development of community health information systems in Zhabei District, Shanghai
Guangrong WANG ; Guiying WU ; Derong PENG ; Zhe LI ; Guodong TIAN
Chinese Journal of Hospital Administration 2010;26(11):812-814
The paper covered the development, structure, functionality, effectiveness and goals of the community health information system in the district. It is found that Zhabei district has developed the standard electronic health archives which can be collected by various sources and renewed instantly;regional health information sharing and collaboration platform has been established as well; a sharing and joint service platform has been built for regional health information sharing between communities and secondary hospitals shared; "Health key" has been developed as a model for self-service health management for residents.
4.Transarterial embolization of congenital pelvic arteriovenous malformation in a male(A case report and review of the literature)
Shengli CHEN ; Zhichen WANG ; Guodong CHEN ; Xi TIAN
Journal of Interventional Radiology 2001;0(05):-
A case of congenital pelvic arteriovenous malformation in a 41-years-old male treated by successful transarterial embolization was reported.This patient suffered from adult polycystic kidney disease and unknown reason for gross hematuria for four years.His left kidney was resected one year ago for suspected left nephrorrhagia but the hematuria remained.MRI examination of pelvis demonstrated AVM involving extensively the pelvic soft tissue,bladder and seminal vesicles.Bilateral internal iliac arterial angiography by DSA showed congenital pelvic arteriovenous malformations(CPAVM),the fringy anisotrophy vascular plexus supplied by many feeding arteries and drained into bilateral dilated and tortuous internal iliac venous branches.Super-selective catheterization and embolization for eight supplying blood branches,such as bilateral internal pudendal arterial branches,right obturator arterial branches,right inferior gluteal arterial branches,left superior vesical artery,left inferior vesical artery,spermatocyst artery and right lateral sacral artery etc,were carried out successfully with gelfoam sponge or PVA particulates in one time.His urine turned clear on the same day after arterial embolization,and no gross hematuria occurred during 6-months follow-up.The pelvic arterial angiography with embolization is extremely effective for the diagnostic and therapeutic measure of CPAVM.
5.Application of Mutislice CT angiography in cervical vascular diseases
Longhai TIAN ; Wencai HUANG ; Chun HUANG ; Guodong LI
Chinese Medical Equipment Journal 2003;0(10):-
Objective To discuss the clinical value of Mutislice CT angiography (MSCTA)in cervical vascular diseases. Methods 60 patients highly suspected suffering cervical vascular diseases,were implemented 16-slices spiral CT angiography of cervical vascular,and blood vessel reconstruction and analysis were done subsequently. Results 43 cases with cervical vascular abnormality were presented in the 60 patients,who were implemented MSCTA. Positive ratio was 71.7%. 171 pieces vessel stenosis were detected among 240 pieces carotid artery and vertebra artery, and 4 cases carotid artery aneurysm and 1 case AVM were found also. Conclusion MSCTA is a convenient and shortcut modality to inspect cervical vascular diseases, and the blood vessel can be observed 3-dimensionally and in any direction in high quality reconstruction images.
6.Analysis on the development of commercial health insurance amid the ongoing health reform
Youhua YAO ; Wenhong ZONG ; Guodong TIAN ; Yuexing LIU
Chinese Journal of Hospital Administration 2011;27(12):929-932
An analysis of policy support for commercial health insurance,its interface with social insurance,and compensation risk control.Recommendations:laws and regulations commercial health insurance,with supportive government taxation policies; clear definition of social medical insurance and commercial health insurance,with commercial health insurers innovating their products and enriching the assurance; information sharing between insurers and medical institutions,bridging the two and encouraging commercial ones to play a role in health management.
7.Research on the cost estimation of community medical aid programs for the urban poor
Linshan XU ; Xiaoming CHENG ; Guodong TIAN ; Al ET
Chinese Journal of Hospital Administration 1996;0(06):-
Objective To estimate the cost of community medical aid programs for the urban poor in Shenyang, Chengdu, Xining and Yinchuan so as to provide the primary basis for improving the compensation mechanisms for such programs. Methods A survey was made on the cost consumption of six major categories in the course of health service delivery and the amount of various community health services actually delivered by the pilot community health service institutions in 2003. The cost of each service program was estimated and then the cost of medical aid programs for the urban poor was estimated. Results The per capita cost of the medical aid programs for the poor in the cities was less than 5 yuan and the total cost of the medical aid programs accounted mostly for 0.05‰ or so of the financial expenditure of each of the cities. Conclusion The government ought to make rational compensation for community medical aid programs, the cost of which is low. Setting up community health service based mechanisms of medical aid for the poor conforms to the actual condition of our country.
8.The mechanism played by 1,25-dihydroxyvitamin D3 in treating renal fibrosis in diabetic nephropathy
Rui YU ; Ye YANG ; Yanyan TIAN ; Yuanyuan ZHANG ; Guodong LYU ; Jia ZHU ; Lati XIAO ; Jun ZHU
Chinese Journal of Endocrinology and Metabolism 2015;(9):793-799
Objective To observe the effects of 1,25-dihydroxyvitamin D3 on the expressions of transforming growth factor-β1(TGF-β1), fibronectin(FN),and vascular endothelial growth factor(VEGF) in rats with diabetic nephropathy(DN), and to elucidate the protective mechanism played by 1,25-dihydroxyvitamin D3. Methods DN models were estabolished by injecting streptozotoein ( STZ ) into male SD rats, which were divided into TGF-β1 overexpression group, TGF-β1 overexpression plus vitamin D3 group, TGF-β1 low-expression group, TGF-β1 low-expression plus vitamin D3 group, TGF-β1 normal-expression group, and TGF-β1 normal-expression plus vitamin D3 group. After 1,25-dihydroxyvitamin D3 treatment for 37 days, renal function and blood biochemical parameters were evaluated. The morphology and fibrosis of kidney tissues were observed. The expressions of TGF-β1, FN, and VEGF in kidney cortex were measured by immunohistochemistry, realtime PCR, and Western blotting. Results The levels of cholesterol, triglyceride, creatinine,plasma glucose, HbA1C , and 24 h urinary protein were lower in vitamin D3treated groups than those in corresponding control groups(P<0. 05). The degree of renal fibrosis was raised with the increased level of TGF-β1. Vitamin D3 treatment decreased the fibrosis in diabetic kidney. There were significant differences in the mRNA and protein expressions of TGF-β1 in three control groups(P<0. 05). With the increased levels of TGF-β1, the expressions of FN and VEGF were increased. The expressions of TGF-β1, FN, and VEGF were lowered by vitamin D3compared with the corresponding control groups(P<0. 05). Conclusion 1,25-dihydroxy-vitamin D3 may protect the renal tissure in diabetic rats via inhibiting the expressions of TGF-β1, FN, and VEGF in the kidney.
9.Detection and clinical significance of combined measurement of serum tumor markers in patients with lung cancer
Xianwen ZHAO ; Cunzhi HAN ; Jiexian JING ; Lili DU ; Baoguo TIAN ; Guodong LI ; Zhongshu ZHANG
Cancer Research and Clinic 1997;0(03):-
Objective To study the clinical diagnosis value and the clinical significance of combined measurement of CEA, DR70, NSE and CYFRA21- 1 in patients with lung cancer. Methods The serum levels of CEA, DR70, NSE and CYFRA21- 1 were determined by ELISA in 130 patients with lung cancer, 50 patients with benign pulmonary disease and 100 cases of normal controls. Results The levels of serum CEA, DR70, NSE and CYFRA21- 1 in lung cancer patients were significantly higher than that in benign pulmonary disease patients and controls (P
10.Optimization of services at urban community health centers using the electronic medical record system
Guiying WU ; Xinping ZHAO ; Zhe LI ; Guodong TIAN ; Weizhen SHEN ; Derong PENG
Chinese Journal of Hospital Administration 2012;28(5):338-341
An electronic medical record(EMR)system is built at urban community health centers to optimize services,achieving information integration of outpatient medical services based on the doctors' workstation.This system has optimized service at the outpatient clinics in the following:1.Digitizing service processes for higher efficiency and service quality; 2.Using EMR templates to save doctors' time in writing medical records for more of their time in patient inquiries and checks; 3.Using LIS,PACs and ECG/EKC systems to check lab results and imaging diagnostics of patients; 4.Using the diagnostic and therapy record sub-system to check electronic records of the patients for consulting their health history;5.Using the Shanghai Medical Alliance's(SMA)shared sub-system to acquire patients' medical records at SMA medical institutions,learning their conditions for their therapies.EMR,when it is built and put into use,can help improve GP's diagnostics and therapeutics,and provide better care to the outpatients as well.