1.The diagnosis value of rheumatoid factor and anti-cyclic citrullinated peptide antibodies in patients with rheumatoid arthritis
Chinese Journal of Primary Medicine and Pharmacy 2010;17(10):1309-1310
Objective To evaluate the value of joint inspection of rheumatoid factor ( RF) and anti-cyclic citrullinated peptide antibodies(anti-CCP antibody) in rheumatoid arthritis( RA). Methods 125 patients with rheumatic disease were selected,including RA 78 cases,non-RA 47 cases. The quantitative ELISA to detect anti-CCP antibody, latex agglutination to test RF,and the data was analyzed. Results Anti-CCP antibody positive rate was 66. 7% ,RF was 74.4% Joint detection was 62.8% , single positive rate of joint detection was not statistically significant, but the specificity of joint detection was 98.6%,positive likelihood ratio was 29.2, significantly improved compared to individual testing;Sensitivity was 49.6%,negative predictive value was 54% ,significantly lower compared to test a-lone. Conclusion Combined detection was able to improve the specificity,positive likelihood ratio and reduce sensitivity , negative predictive value. It was more useful.
2.Probe into establishment of voluntary reporting system of nursing errors
Xia GUO ; Wei ZHOU ; Yongbin JIAN
Chinese Journal of Hospital Administration 2011;27(2):124-127
Errors and flaws of clinical nursing practice can be fully exposed to voluntary reporting system of nursing errors, and then dramatically improving patient safety. This paper aims at exploring the theoretical basis, the characteristic of the system and essentiality for establishing voluntary reporting system of nursing errors, introducing the methods practicing both in abroad and in domestic, explaining its precondition and put forward a suggestion that the voluntary reporting system would be established in our own country.
3.Cases of benzene-related leukemia reported in periodicals in China and analysis of diagnosis.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(11):844-847
Adolescent
;
Adult
;
Benzene
;
toxicity
;
China
;
Female
;
Humans
;
Leukemia
;
chemically induced
;
diagnosis
;
Male
;
Middle Aged
;
Occupational Exposure
;
Young Adult
5.Investigation in evaluation of various capacity requirement of probationer nursing students by nurses in operation room
Li GUO ; Shuo WANG ; Hui ZHOU ; Xuan WEI ; Wei HE
Chinese Journal of Practical Nursing 2009;25(8):14-16
Objective To investigate in evaluation of various capacity requirement of probationer nurs-ing students by nurses in operation room in order to improve clinical teaching work. Methods A self-de-signed questionnaire was applied, 191 qualified teaching nurses from nine grade three A general hospitals in Beijing were invited to fdl the questionaires. The results underwent subsequent analysis. Results The teach-ers had high expectations for various capacity of the probationer nursing students. Conclusions Clinical teachers should establish feasible teaching scheme according to the existing teaching syllabus in order to in-crease teaching quality, make students gain new insights through reviewing old materials, so that they can mas-ter various technique in operation room in short time.
6.Construction and characterization of a novel recombinant retroviral vector expressing mouse T-bet.
Xuejie ZHANG ; Jianhua ZHANG ; Wei ZHANG ; Jie GUO ; Xuyu ZHOU
Chinese Journal of Biotechnology 2014;30(10):1586-1593
In order to study T-bet function in mouse cells, a novel retroviral vector expressing mouse T-bet and reporter gene Thy1.1 was constructed. Retrovirus particles were then produced by transfection of the recombinant retroviral plasmid into a packaging cell line Platinum-E. The recombinant retrovirus played considerable infection ability. T-bet expression was then identified by FACS after infection of CD4+ primary T cells from T-bet knockout mouse with recombinant retrovirus. To determine if exogenous expressing T-bet has normal function, we checked the expression level of T-bet target gene, Ifng. IFN-y expression was upregulated in the T-bet knockout T cells infected with recombinant retrovirus. In conclusion, we successfully constructed an effective mouse T-bet recombinant retroviral vector.
Animals
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Cell Line
;
Genetic Vectors
;
Interferon-gamma
;
metabolism
;
Mice
;
Mice, Knockout
;
Recombinant Proteins
;
biosynthesis
;
Retroviridae
;
T-Box Domain Proteins
;
biosynthesis
;
T-Lymphocytes
;
metabolism
;
Transfection
7.Acute toluene or xylene poisoning case analysis of domestic journals.
Jian-shu HUANG ; Yuan-ling ZHOU ; Wei-guo WAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(5):369-371
Acute Disease
;
Adolescent
;
Adult
;
Aged
;
Female
;
Humans
;
Male
;
Middle Aged
;
Toluene
;
poisoning
;
Xylenes
;
poisoning
;
Young Adult
8.The relationship among structural empowerment, nurses' job stress and burnout
Jiajia GUO ; Zuoxia ZHOU ; Hui ZHAO ; Wei WANG
Chinese Journal of Practical Nursing 2013;(3):31-35
Objective To investigate the status of structural empowerment,job stress and burnout,and to explore the relationship aunong them.Methods The questionnaires of CWEQ-Ⅱ,job stressors and MBI were used to investigate 350 nurses working at tertiary-level hospitals.Results The average score of CWEQ-Ⅱ was (2.23±0.59),the score of EE of MBI was (29.75±13.94),PA was (27.40±11.21),both of them showed a high level of exhaustion,DP was (8.07±5.82),which showed a middle level of exhaustion.The findings showed that workload and time pressure were the most frequently encountered job stressor among staff nurses,the score was (3.23±0.95).There was a significant correlation among structural empowerment,job stressors and the level of burnout.Hierarchical regression analysis and structural equation modeling showed that structural empowerment had significant influence on every factor of job stressors and burnout,job stressors had significant influence on the every factors of burnout.Conciusins It is suggested to pay attention to the main job stressors,and take proper interventions to enhance nurses' structural empowerment to prevent burnout,and thereby to raise the quality of care.
9.Progress in Mucosal Adjuvants
Hong-Li ZHOU ; Li GUO ; Jian-Wei WANG ; Tao HONG ;
China Biotechnology 2006;0(03):-
Mucosal adjuvants play important roles in vaccine development. By now, the common used mucosal adjuvants can be divided into three categories: the bacterial derivatives, cytokines and chemokines, and antigen delivery systems. Progresses of the three kinds of adjuvants were reviewed to give a reference to novel vaccine research.
10.Research Advance on Marinomonas
Li WEI ; Jun-Chu ZHOU ; You-Guo LI ;
Microbiology 1992;0(01):-
In this mini review,some research advance on Marinomonas from domestic and overseas was briefly summarized,mainly including of its classification、ecological distribution、functional genes and bioactive molecules.Furthermore,some suggestion and perspectives for further studies on Marinomonas were also proposed.