1.EFFECT OF STEAM-HEATED PROCEDURE ON IMMUNOGENICITY OF MAJOR SOYBEAN ANTIGENIC PROTEINS IN WHOLE FAT SOYBEAN
Zewei SUN ; Guixin QIN ; Qinghua ZHANG
Acta Nutrimenta Sinica 2004;0(06):-
Objective: To study the effect of steam-heated procedure on immunogenicity of major antigenic proteins in soybean. Method: Twelve newborn calves were randomly divided into 3 groups (Group A, B and C). Each group of the calves were fed on the diets containing raw soybean flour, heated soybean flour and whole milk, respectively. The glycicin, ?-conglycinin and neighbor collection as antigens, antibodies specific to soy allergens were detected by ELISA. Results: (1) The weight gain was A
2.Textual Research on Traditional Effect Verification of Belamcanda chinensis and Its Pharmacological Experimental Verification
Wen WEN ; Yuehai MA ; Jinghe ZHU ; Guixin ZOU ; Wenyan QIN ; Guoxin LI
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(5):846-850
Through reviewing ancient and modern literatures,the effect evolution and disease treatment changes of Belamcanda chinensis were understood.The pharmacological experiments were used to verify its main effects.The combination of featured advantages of traditional Chinese medicine (TCM) and modern science and technology contributed to the promotion of TCM modernization.It had important significance for the development of effective components,selection of disease types in the treatment for research and development of new TCM drugs.The indication of Belamcanda chinensis was verified from textual research.The treatment of disease types by Belamcanda chinensis was verified from medical books.The treatment of disease types by Belamcanda chinensis compound was analyzed based on the Pujifang database management system.Main indications of Belamcanda chinensis were summarized.Modern pharmacological studies on anti-inflammatory mechanism of main components of Belamcanda chinensis were combined to screen animal models and investigation indexes for the preliminary verification of the efficacy of Belamcanda chinensis.The comprehensive application of classical herbal medicine books and prescription database analysis results showed that removing phlegm and relieving sore throat were the efficacy of Belamcanda chinensis,which was an important medicine in the treatment of pharyngitis and sore throat.In the modern research,serum of experimental group,IL-4 in throat tissues,as well as IgE and LTC4 level in serum and lung tissues were significantly reduced compared to the model group (P<0.05).It was concluded that the treatment effect of Belamcanda chinensis extract to chronic pharyngitis may be through the decreasing of IgE level in serum and lung tissues,inhibiting IL-4 expression in serum and throat tissues,and the LTC4 expression in serum.
3.Clinical application of severe multiple trauma treatment model based on damage control strategy
Lunxian TANG ; Zhongmin LIU ; Guixin SUN ; Zengchun LI ; Hong SUN ; Xiaowei BAO ; Chunmei WANG ; Shengchao JI ; Qin SHAO ; Jianwen BAI
Chinese Journal of Emergency Medicine 2019;28(8):962-965
Objective To study the superiority of severe multiple trauma treatment model based on damage control strategy. Methods In the intergrated injury first-aid mode, the intensive care unit-guided damage control strategy was used to treat severe multiple trauma. Results A total of 789 severe multiple damage patients were treated with damage control strategies in our hospital from December 2018 to December 2018. Sixty-nine patients died and the survival rate was 91.25%. Conclusions The intensive care unit-guided trauma control strategy has a satisfactory clinical effect in the treatment of patients with severe multiple trauma.
4.Individualized plasticity autograft mimic with efficient bioactivity inducing osteogenesis.
Yan WEI ; Guixin ZHU ; Zifan ZHAO ; Chengcheng YIN ; Qin ZHAO ; Hudi XU ; Jinyang WANG ; Jinglun ZHANG ; Xiaoxin ZHANG ; Yufeng ZHANG ; Haibin XIA
International Journal of Oral Science 2021;13(1):14-14
Mineralized tissue regeneration is an important and challenging part of the field of tissue engineering and regeneration. At present, autograft harvest procedures may cause secondary trauma to patients, while bone scaffold materials lack osteogenic activity, resulting in a limited application. Loaded with osteogenic induction growth factor can improve the osteoinductive performance of bone graft, but the explosive release of growth factor may also cause side effects. In this study, we innovatively used platelet-rich fibrin (PRF)-modified bone scaffolds (Bio-Oss
Autografts
;
Bone Regeneration
;
Cell Differentiation
;
Humans
;
Mesenchymal Stem Cells
;
Osteogenesis
;
Tissue Engineering
;
Tissue Scaffolds