Hypertension is a kind of chronic disease effecting many population, and its prevalence has a rising trend with the age. It keeps in a increasing trend in chinese population, and follows high rates of prevalence, mortality, morbidity and three low rates of wareness, treatment, control. Hypertension is caused by a number of factors, and its incidence is closely related with unhealthy diets. Its incidence may be decreasing gradually by changing lifestyles, taking healthy and reasonable diet. To provide some basic data of healthy lifestyles and diet for people, describe and summarize the relation of hypertension and diets in this article.

Objective To investigate risk factors of type 2 diabetes mellitus complicated with carotid atherosclerosis and analysis of neutrophil to lymphocyte ratio and platelets to lymphocyte ratio levels.Methods A total of 125 type 2 diabetes patients in our hospital were selected as research objects,including 60 type 2 diabetes cases as control group,and 65 type 2 diabetes mellitus patients complicated with carotid atherosclerosis as observation group,risk factors and NLR,PLR levels of two groups were compared.Logistic regression analysis were used to analyze the risk factors of type 2 diabetes with carotid atherosclerosis.Results No significant differences were observed in BUN,Cr,HDL,UA levels between the two groups (P ＞ 0.05).The observation group had higher SBP,DBP,TG,TC,CRP and LDL,and lower HbA1 c and FPG than the control group,and the differences between the two groups were statistically significant (P ＜ 0.05).The levels of NLR and PLR in the control group were lower than that of the observation group (P ＜ 0.05).Logistic regression analysis showed that elevated levels of LDL,SNP,SBP,NLR and PLR were risk factors of carotid atherosclerosis in type 2 diabetes mellitus patients.Conclusion Carotid atherosclerosis in type 2 diabetes mellitus,SBP,DBP,TG,TC,HbA1c,FPG and CRP are closely related to CRP.

Objective To investigate risk factors of type 2 diabetes mellitus complicated with carotid atherosclerosis and analysis of neutrophil to lymphocyte ratio and platelets to lymphocyte ratio levels.Methods A total of 125 type 2 diabetes patients in our hospital were selected as research objects,including 60 type 2 diabetes cases as control group,and 65 type 2 diabetes mellitus patients complicated with carotid atherosclerosis as observation group,risk factors and NLR,PLR levels of two groups were compared.Logistic regression analysis were used to analyze the risk factors of type 2 diabetes with carotid atherosclerosis.Results No significant differences were observed in BUN,Cr,HDL,UA levels between the two groups (P ＞ 0.05).The observation group had higher SBP,DBP,TG,TC,CRP and LDL,and lower HbA1 c and FPG than the control group,and the differences between the two groups were statistically significant (P ＜ 0.05).The levels of NLR and PLR in the control group were lower than that of the observation group (P ＜ 0.05).Logistic regression analysis showed that elevated levels of LDL,SNP,SBP,NLR and PLR were risk factors of carotid atherosclerosis in type 2 diabetes mellitus patients.Conclusion Carotid atherosclerosis in type 2 diabetes mellitus,SBP,DBP,TG,TC,HbA1c,FPG and CRP are closely related to CRP.

Objective To evaluate the effect of conversion from mycophenolic acid (MPA) to mizoribine (MZR) in renal transplant recipients with gastrointestinal tract (GI) symptoms.Methods A total of 355 renal transplant recipients with GI symptoms caused by MPA administration were enrolled from April 2015 to March 2017 in 25 different renal transplant centers in China.The symptomatic improvement of GI before (baseline) and after conversion to MZR (1,2,4 weeks) was assessed by each item of GI symptoms indication.In addition,the efficacy and safety of the conversion therapy during 12 months were determined.Results Patients showed improvement in GI symptoms including diarrhea,abdominal pain,abdominal distention and stomachache after conversion to MZR 1,2,4 weeks (P＜0.05).In patients with different severity of diarrhea,conversion to MZR therapy significantly improved diarrhea (P＜0.05).During 12 months,no patient experienced clinical immune rejection.We did not observe any infections,leucopenia and other serious side effects.Conclusion MZR could markedly improve GI symptoms caused by MPA administration in renal transplant recipients.

Objective:To summarize the patient profiles and therapeutic efficacies of ABO-incompatible living-related kidney transplantations at 19 domestic transplant centers and provide rationales for clinical application of ABOi-KT.Methods:Clinical cases of ABO-incompatible/compatible kidney transplantation (ABOi-KT/ABOc-KT) from December 2006 to December 2009 were collected. Then, statistical analyses were conducted from the aspects of tissue matching, perioperative managements, complications and survival rates of renal allograft or recipients.Results:Clinical data of 342 ABOi-KT and 779 ABOc-KT indicated that (1) no inter-group differences existed in age, body mass index (BMI), donor-recipient relationship or waiting time of pre-operative dialysis; (2) ABO blood type: blood type O recipients had the longest waiting list and transplantations from blood type A to blood type O accounted for the largest proportion; (3) HLA matching: no statistical significance existed in mismatch rate or positive rate of PRA I/II between two types of surgery; (4) CD20 should be properly used on the basis of different phrases; (5) hemorrhage was a common complication during an early postoperative period and microthrombosis appeared later; (6) no difference existed in postoperative incidence of complications or survival rate of renal allograft and recipients at 1/3/5/10 years between ABOi-KT and ABOc-KT. The acute rejection rate and serum creatinine levels of ABOi-KT recipients were comparable to those of ABOc-KT recipients within 1 year.Conclusions:ABOi-KT is both safe and effective so that it may be applied at all transplant centers as needed.