OBJECTIVE: To provide reference for the development of pharmaceutical research in pharmacy department of stomatology hospital.METHODS: SWOT analysis was applied to analyze advantage,disadvantage,opportunities and threats of the development of pharmaceutical research in pharmacy department of our hospital.The development strategy of pharmaceutical research was investigated based on current research work.RESULTS: The advantages were fruitful oral disease resources and high informationization degree,etc.The disadvantages were weak hardware and non-professional scientific researchers,etc.The opportunities were that research was guaranteed by law and oral preparations were required in the clinic.The threats were that the situation of preparations development was serious.CONCLUSIONS: Pharmacy department should take internal advantage and external opportunities to develop pharmaceutical research in line with local conditions.

OBJECTIVE:To determine the contents of chlortetracycline hydrochloride and tetracaine hydrochloride in compound chlortetracycline hydrochloride ointment.METHODS:Dual wavelength spectrophotometry was used to determine the two components.The absorbance of the two components was determined at wavelength of 311 nm,368 nm and 387.5 nm,respectively;and the contents of which were computed as well.RESULTS:The linear ranges for chlortetracycline hydrochloride and tetracaine hydrochloride were 9.90～29.71 ?g?mL-1 and 5.99～17.98 ?g?mL-1(r=0.999 9),respectively,with average recovery rates at 99.37%(RSD=0.31%,n=9) and 98.31%(RSD=0.23%,n=9),respectively.CONCLUSION:The method is simple,rapid and accurate,and suitable for the determination of compound chlortetracycline hydrochloride ointment.

OBJECTIVE: To study the feasibility of conducting hospital pharmaceutical inspection by pharmacy pharmaceutical management group.METHODS: The experience of conducting hospital pharmaceutical inspection including monitoring the drug control in clinical departments,supervising the drug control in pharmacy department and monitoring rational use of drugs was introduced.RESULTS & CONCLUSIONS: Pharmaceutical inspection promoted drug management in pharmacy and clinical departments,improved the rational use of drugs,and strengthened the relationship between pharmacy and clinical departments,which deserves to be popularized.

OBJECTIVE:To study the current situation and developing trend of the drug utilization in outpatients with oral diseases. METHODS:By a retrospective method,the drug utilization data in outpatient pharmacy of our hospital from 2005 to 2007 were analyzed statistically. RESULTS:The drug varieties used remained stable. Chinese traditional patent drugs,anti-microbial drugs,anesthetics and special drugs(for patients from different departments) dominated the first 4 places in consumption sum,and they accounted for 92.4% of the 3 years. The consumption sum of top 15 drugs accounted for 79.7% of the total. Except for anti-microbial drugs,the other three categories were of high DDDs. The drugs for oral mucosal disease occupied a dominant position in terms of consumption sum,and most of which were Chinese traditional patent drugs. CONCLUSION:The drug utilization structure in outpatients with oral diseases accord with therapeutic rule of oral diseases. Pharmaceutical factiories should develop more Chinese patent medicines for oral mucosal disease.

OBJECTIVE:To provide references for the elevation of the inconsistency between the accounts and the numbers of drugs by computer management in inpatient dispensary in our hospital.METHODS:Three stages including drug checking,stockout and stockin were analyzed to find out the causes for the inconsistency between the accounts and the numbers of drugs,aimed at which the countermeasures were put forward.RESULTS & CONCLUSIONS:The consistency between the accounts and the numbers of drugs could be greatly elevated by adopting special messenger responsible system,arranging reasonable drug stocktaking time,evolving stockin and stockout system as well as strengthening the responsibility of the concerned personnel.

OBJECTIVE:To investigate the use of drugs in the inpatients undergoing oral and maxillofacial surgery in our hospital for references of rational drug use.METHODS:The drugs used in the inpatients undergoing oral and maxillofacial surgery in our hospital during 2006 were analyzed statistically in respect of sum of money,the quantities of drugs and DDDs etc.RESULTS:Narcotics,anti-infectives and drugs affecting electrolyte balance and acid-base balance ranked among the first in terms of consumption sum,accounting for 30.18%,24.60%,and 16.12%,respectively.Leading the first 3 places in terms of co-nsumption sum were propofol injection,cefuroxime sodium for injection and sodium chloride injection.Vitamin C injection,benz-ylpenicillin sodium for injection and sodium chloride injection ranked at the top 3 in terms of DDDs.CONCLUSION:Only a few kinds of drugs were used for the inpatients undergoing oral and maxilla facial surgery in our hospital.Of which,narcotics,anti-infectives and drugs affecting electrolyte balance and acid-base balance were predominantly used,and intravenous administration was the chief route of administration.It is necessary to strengthen the rational use of anti-infectives in our hospital.