Objective:To observe the influence of electroacupuncture at Shu-points of the Five Zang-organ in domestic rabbits with acute allergy neuritis,a classical animal model,and to explore the immunoregulatory mechanism responsible for the regimen by detecting expression of the costimulatory molecules in sciatic nerve.Methods:ELISA was used to examine proteins of CD28,CTLA-4,B7-1,B7-2 in sciatic nerve of P2 immunized EAN domestic rabbits.Results:It was showed that the expression of CTLA-4 and B7-2 was obviously up-regulated(P

Acupuncture Points ; Acupuncture Therapy ; Female ; Hirschsprung Disease ; therapy ; Humans ; Infant

Objective: To research the clinical curative effect and explore the mechanism of penetrating of scalp-point on acute hypertensive intracerebral hemorrhage (ICH). Methods: 66 patients were randomly divided into two groups: one is the scalp-point therapeutic group, the other is the western medicine group. The two groups were all treated by dehydration, etc. In addition, there are 20 normal people to be set as the healthy group. To select the nervous functional deficit mark, activity of daily living (ADL) form, the amount S-100B protein as indexes and analysis the results. Results: the recordings indicate the patients' Serum S-100B protein are related with nervous functional deficiency mark. After 28 days, the recovery of patients' nervous function of scalp acupuncture group was obviously superior to that of control group (P＜0.05). Conclusions: The results suggested that the patients' Serum S-100B had positive correlation with nervous functional deficit; The penetrating of scalp-point had the better regulatory effect on the level of Serum S-100B, and could improve the nervous functional deficit and ADL, so as to improve the coordination and compensation function and the general nervous function between cortical functional areas

Objective To observe the clinical efficacy of acupuncture with points selection based on yin-yang and qi-blood in treating insomnia by using polysomnography.Method Seventy-five insomnia patients were randomized into a treatment group of 38 cases and a control group of 37 cases. The treatment group was intervened by acupuncture with points selection based on yin-yang and qi-blood, while the control group was by oral administration of Estazolam. The polysomnography was used to assess sleep condition before and after 2 treatment courses, and the clinical efficacies were compared between the two groups.Result The sleep parameters [sleep latency, rapid eye movement (REM) latency, total sleep duration, and sleep efficiency) were significantly changed after the treatment in both groups (P<0.01). The Non-REM (NREM) and REM duration of the treatment group were significantly changed after the treatment (P<0.01). The REM duration of the control group was significantly changed after the treatment (P<0.01). After the treatment, the NREM and REM durations of the treatment group were significantly different from that of the control group (P<0.01). The sleep durations in S1, S2, S3, and S4 stages during NREM were significantly changed in the treatment group after the intervention (P<0.01). The sleep duration in S1, S2 during NREM was markedly changed in the control group after the intervention (P<0.01 ,P<0.05). After the treatment, the sleep durations in S1, S2, S3, and S4 during NREM of the treatment group were significantly different from that of the control group (P<0.01). The total effective rate was 73.7% in the treatment group versus 75.7% in the control group, and the difference was statistically insignificant (P>0.05).Conclusion Acupuncture with points selection based on yin-yang and qi-blood is effective in treating insomnia, and it can improve the sleep structure and quality.

This article summarizes the literature about studies onToll-like receptor 2and acupuncture points and explores thecorrelationand action of Toll-like receptor 2inacupuncture information start-up and conduction mechanism from the biological characteristics of Toll-like receptor 2and the relationship of Toll-like receptor 2-mediated signal pathways tomast cells, acupuncture effects and the immuno-neuro-endocrine network.

OBJECTIVETo observe differences of immediate effect of twirling reinforcing-reducing manipulation at head acupoints on muscle force in patients with acute ischemic stroke.

METHODSA total of 126 patients who met the inclusive criteria were randomly divided into a twirling reinforcing group, a mild reinforcing-reducing group and a twirling reducing group, 42 cases in each one. The lines between Baihui (GV 20) and bilateral Taiyang (EX-HN 5) were selected and treated with successive insertion of three needles. The twirling reinforcing method was used in the twirling reinforcing group, and mild reinforcing-reducing method was used in the mild reinforcing- reducing group, and twirling reducing method was used in the twirling reducing group. Each needle was manipulated for 1 min, which was repeated once every 10 min. The needles were retained for 30 min. Muscle force was evaluated immediately after treatment.

RESULTS(1) Muscle force of upper limb: after acupuncture, the muscle force of proximal and remote ends were all improved significantly in three groups (all P < 0.05), which was more obvious in proximal end (all P < 0.05). The improvement of the muscle force of proximal end in the twirling reinforcing group was superior to those in the mild reinforcing-reducing group and twirling reducing group (both P < 0.05); the differences of the muscle force of remote end were not significant among three groups (all P > 0.05). (2) Muscle force of lower limb: after acupuncture, the muscle force of proximal and remote ends was all improved significantly in the three groups (all P < 0.05). The improvement of the muscle force of proximal end was superior to that of remote end in the twirling reinforcing group and mild reinforcing-reducing group (both P < 0.05).

CONCLUSIONThe twirling reinforcing manipulation at head acupoints is superior to mild reinforcing-reducing and twirling reducing manipulation for muscle force in patients with acute ischemic stroke, which is more significant in proximal end of limbs.

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Ischemia ; therapy ; Lower Extremity ; physiopathology ; Male ; Middle Aged ; Stroke ; physiopathology ; therapy ; Treatment Outcome ; Upper Extremity ; physiopathology

Objective:To study the influence of different methods on serum soluble intercellular adhesion molecule1 (sICAM1) in patients with acute cerebral infarction. Methods: Double antibody enzyme-linked immunoadsorbent assay was used. Results and Conclusion: Scalp point-to-point acupuncture has a significant reducing effect on abnormally elevated serum sICAM1 in patients with acute cerebral infarction. Its curative effect is superior to that of simple Western medicine. There is a significant difference between them (P＜0.05).

The authors punctured the acupoints Jianyu (LI 15), Jianliao (TE 14), Jianzhen (SI 9), Binao (LI 14), Quchi (LI 11), Shousanli (LI 10) and Hegu (LI 4) and applied massage to the affected regions to treat 32 cases of the myotenositis of long head of biceps brachii. The results showed 8 cases were cured, 10 cases were remarkably effective, 11 cases were effective and 3 cases got no effect; the total effective rate was 90.6%.

In the treatment of 48 cases of peripheral facial paralysis by puncturing Yangbai (GB 14)toward Yuyao (Ex-HN 4), Dicang (ST 4) toward Jiache (ST 6), Xiaguan (ST 7) toward Jiache (ST 6),Sibai (ST 2) toward Quanliao (SI 18), Baihui (GV 20) toward Taiyang (Ex-HN 5), Yintang (Ex-HN 3)toward Shangen (Ex-HN), Cuanzhu (BL 2) toward Jingming (BL 1), and Hegu (LI 4) toward Laogong (PC 8) on the sick side, with other acupoints added in accordance with the symptoms, the results showed cure in 39 cases, remarkable effect in 7 cases, failure in 2 cases, and the curative rate in 81.2% and the effective rate in 95.8%.

Objective: To investigate the effect of scalp point-through-point acupuncture on 200 kDa neurofilament protein (NF-200) in rats with acute cerebral infarction and explore its mechanism on nerve plasticity in cerebral infarction rats. Methods: Healthy male Wistar rats were randomly allocated to sham operation (Group A), model (Group B) and acupuncture (Group C) groups. A rat middle cerebral artery occlusion (MCAO) model of cerebral ischemia was made. NF-200 mRNA was measured by reverse transcriptase polymerase chain reaction (RT-PCR) in each group on the 7th, 14th and 28th days. Results: The cerebral expression of NF-200 in group C was significantly different from those in groups A and B (P＜0.05); there was a significant difference between groups C and B or A at different time windows (P＜0.01),indicating that scalp point-through-point acupuncture could improve the cerebral expression of NF-200. Conclusion: Scalp point-through-point acupuncture can improve neural function,promote the recovery of limb function and increase the expression of NF-200 after cerebral ischemia, exerting a regulative effect on neuronal plasticity in the brain.